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Academic Journal

In Silico Design of miniACE2 Decoys with In Vitro Enhanced Neutralization Activity against SARS-CoV-2, Encompassing Omicron Subvariants .

  • Authors : Arévalo-Romero JA; Unidad de Ingeniería Celular y Molecular, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud, IDCBIS, Bogotá 111611, Colombia.; Instituto de Errores Innatos del Metabolismo, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/immunology ; COVID-19*/COVID-19*/COVID-19*/virology SARS-CoV-2 variants

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 08; Vol. 25 (19). Date of Electronic Publication: 2024 Oct 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

MSC-extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation.

  • Authors : Al Saihati HA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hafr Albatin, Hafar Al-Batin, Saudi Arabia. .; Dessouky AA

Subjects: COVID-19*/COVID-19*/COVID-19*/therapy ; COVID-19*/COVID-19*/COVID-19*/metabolism ; COVID-19*/COVID-19*/COVID-19*/pathology

  • Source: Stem cell research & therapy [Stem Cell Res Ther] 2024 Sep 20; Vol. 15 (1), pp. 316. Date of Electronic Publication: 2024 Sep 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512

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Academic Journal

In silico analyses identify sequence contamination thresholds for Nanopore-generated SARS-CoV-2 sequences.

  • Authors : Bolaji AJ; Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, Canada.; Cadham Provincial Laboratory, Winnipeg, Canada.

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics ; COVID-19*/COVID-19*/COVID-19*/virology ; COVID-19*/COVID-19*/COVID-19*/transmission

  • Source: PLoS computational biology [PLoS Comput Biol] 2024 Aug 19; Vol. 20 (8), pp. e1011539. Date of Electronic Publication: 2024 Aug 19 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

In-silico discovery of common molecular signatures for which SARS-CoV-2 infections and lung diseases stimulate each other, and drug repurposing.

  • Authors : Alamin MH; Faculty of Science, Department of Statistics, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.; Rahaman MM

Subjects: Drug Repositioning*/Drug Repositioning*/Drug Repositioning*/methods ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics

  • Source: PloS one [PLoS One] 2024 Jul 18; Vol. 19 (7), pp. e0304425. Date of Electronic Publication: 2024 Jul 18 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

In Silico Analyses Indicate a Lower Potency for Dimerization of TLR4/MD-2 as the Reason for the Lower Pathogenicity of Omicron Compared to Wild-Type Virus and Earlier SARS-CoV-2 Variants.

  • Authors : Kircheis R; Syntacoll GmbH, 93342 Saal an der Donau, Germany.

Subjects: COVID-19*/COVID-19*/COVID-19*/virology ; Lymphocyte Antigen 96*/Lymphocyte Antigen 96*/Lymphocyte Antigen 96*/metabolism ; Lymphocyte Antigen 96*/Lymphocyte Antigen 96*/Lymphocyte Antigen 96*/genetics SARS-CoV-2 variants

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 17; Vol. 25 (10). Date of Electronic Publication: 2024 May 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

In silico study of alkaloids with quercetin nucleus for inhibition of SARS-CoV-2 protease and receptor cell protease.

  • Authors : Mohebbi A; Department of Chemical Engineering, Faculty of Engineering, Shahid Bahonar University of Kerman, Kerman, Iran.; Eskandarzadeh M

Subjects: COVID-19* ; Alkaloids*/Alkaloids*/Alkaloids*/pharmacology; Humans

  • Source: PloS one [PLoS One] 2024 Apr 16; Vol. 19 (4), pp. e0298201. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Aspergillus fumigatus secretes a protease(s) that displays in silico binding affinity towards the SARS-CoV-2 spike protein and mediates SARS-CoV-2 pseudovirion entry into HEK-293T cells.

  • Authors : Mjokane N; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.; Akintemi EO

Subjects: Peptide Hydrolases* ; COVID-19*; Humans

  • Source: Virology journal [Virol J] 2024 Mar 06; Vol. 21 (1), pp. 58. Date of Electronic Publication: 2024 Mar 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X

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Academic Journal

Anticancer and Biological Effects of Some Natural Compounds and Theoretical Investigation of them Against RdRP of SARS-COV-2: In Silico and In Vitro Studies.

  • Authors : Zhang J; Department of Oncology, Shenzhen Bao'an Traditional Chinese Medicine Hospital, Shenzhen, 518000, China.; Department of Oncology, The First Clinical Medical College of Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.

Subjects: Ovarian Neoplasms* ; COVID-19*; Humans

  • Source: Molecular biotechnology [Mol Biotechnol] 2023 Nov; Vol. 65 (11), pp. 1764-1776. Date of Electronic Publication: 2023 Feb 13.Publisher: Springer Country of Publication: Switzerland NLM ID: 9423533 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Application of in-silico drug discovery techniques to discover a novel hit for target-specific inhibition of SARS-CoV-2 Mpro's revealed allosteric binding with MAO-B receptor: A theoretical study to find a cure for post-covid neurological disorder.

  • Authors : Zaki MEA; Faculty of Science, Department of Chemistry, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.; Al-Hussain SA

Subjects: COVID-19* ; Nervous System Diseases*; Humans

  • Source: PloS one [PLoS One] 2024 Jan 16; Vol. 19 (1), pp. e0286848. Date of Electronic Publication: 2024 Jan 16 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

An Integrated In Silico and In Vitro Approach for the Identification of Natural Products Active against SARS-CoV-2.

  • Authors : Pennisi R; Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.; Gentile D

Subjects: COVID-19* ; Biological Products*/Biological Products*/Biological Products*/pharmacology; Humans SARS-CoV-2 variants

  • Source: Biomolecules [Biomolecules] 2023 Dec 28; Vol. 14 (1). Date of Electronic Publication: 2023 Dec 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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