نتائج البحث

Natural-Target-Mimicking Translocation-Based Fluorescent Sensor for Detection of SARS-CoV-2 PLpro Protease Activity and Virus Infection in Living Cells.

• Authors : Sokolinskaya EL; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.; Ivanova ON

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/metabolism ; COVID-19*/COVID-19*/COVID-19*/virology ; COVID-19*/COVID-19*/COVID-19*/diagnosis

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 17; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Pharmacotherapeutic Potential of Natural Products to Target the SARS-CoV-2 PLpro Using Molecular Screening and Simulation Approaches.

• Authors : Sayaf AM; School of Chemical Sciences, Universiti Sains Malaysia, 11800 USM, George Town, Penang, Malaysia.; Ahmad H

Subjects: Biological Products*/Biological Products*/Biological Products*/pharmacology ; Biological Products*/Biological Products*/Biological Products*/therapeutic use ; COVID-19*

• Source: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2023 Nov; Vol. 195 (11), pp. 6959-6978. Date of Electronic Publication: 2023 Mar 24.Publisher: Humana Press Country of Publication: United States NLM ID: 8208561 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.

• Authors : van Vliet VJE; Department of Medical Microbiology, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, South Holland, The Netherlands.; The Roslin Institute, University of Edinburgh, Midlothian, Scotland, United Kingdom.

Subjects: Ubiquitin*/Ubiquitin*/Ubiquitin*/metabolism ; COVID-19*; Humans

• Source: PLoS pathogens [PLoS Pathog] 2022 Dec 22; Vol. 18 (12), pp. e1011065. Date of Electronic Publication: 2022 Dec 22 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Genetically Encoded Fluorescent Sensors for SARS-CoV-2 Papain-like Protease PLpro.

• Authors : Sokolinskaya EL; Center for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Bolshoy Blvd 30, bld. 1, 121205 Moscow, Russia.; Putlyaeva LV

Subjects: COVID-19* ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics; Coronavirus Papain-Like Proteases

• Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 15; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Arylamines QSAR-Based Design and Molecular Dynamics of New Phenylthiophene and Benzimidazole Derivatives with Affinity for the C111, Y268, and H73 Sites of SARS-CoV-2 PLpro Enzyme.

• Authors : Sabadini, Gianfranco¹ (AUTHOR) ; Mellado, Marco² (AUTHOR) ; Morales, César³ (AUTHOR)

• Source: Pharmaceuticals (14248247). May2024, Vol. 17 Issue 5, p606. 15p.

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Identification of natural compounds (proanthocyanidin and rhapontin) as high-affinity inhibitors of SARS-CoV-2 Mpro and PLpro using computational strategies.

• Authors : AlAjmi, Mohamed F.¹; Azhar, Asim²; Hasan, Sadaf³

• Source: Archives of Medical Science. Mar2024, Vol. 20 Issue 2, p567-581. 15p.

تفاصيل العنوان

Natural-Target-Mimicking Translocation-Based Fluorescent Sensor for Detection of SARS-CoV-2 PLpro Protease Activity and Virus Infection in Living Cells

• Authors : Elena L. Sokolinskaya; Olga N. Ivanova; Irina T. Fedyakina

Subjects: COVID-19; SARS-CoV-2; coronavirus

• Source: International Journal of Molecular Sciences, Vol 25, Iss 12, p 6635 (2024)

تفاصيل العنوان

Arylamines QSAR-Based Design and Molecular Dynamics of New Phenylthiophene and Benzimidazole Derivatives with Affinity for the C111, Y268, and H73 Sites of SARS-CoV-2 PLpro Enzyme

• Authors : Gianfranco Sabadini; Marco Mellado; César Morales

Subjects: SARS-CoV-2; COVID-19; coronavirus

• Source: Pharmaceuticals, Vol 17, Iss 5, p 606 (2024)

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Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV‑2

• Authors : Santos, Lucianna H; Kronenberger, Thales; Almeida, Renata G

Subjects: Medicinal and Biomolecular Chemistry; Chemical Sciences; Prevention

• Source: Journal of Chemical Information and Modeling. 62(24)

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Molecular dynamics-driven exploration of peptides targeting SARS-CoV-2, with special attention on ACE2, S protein, Mpro, and PLpro: A review.

• Authors : SABRI, MOHAMAD ZULKEFLEE¹; BOJARSKA, JOANNA²; FAI-CHU WONG^3,4

• Source: Biocell. 2023, Vol. 47 Issue 8, p1727-1742. 16p.

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