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Subject : computational biology

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Whole genome analysis of more than 10 000 SARS-CoV-2 virus unveils global genetic diversity and target region of NSP6

Authors : Debasree Maity; Kaushik Mitra; Nikhil Sharma

Subjects: NSP6; AcademicSubjects/SCI01060; Population

Source: Briefings in Bioinformatics

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A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico investigation

Authors : Shafi Mahmud; Zulkar Nain; Asif Shahriar

Subjects: Models, Molecular; Drug; Pyrrolidines

Source: Briefings in Bioinformatics

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Ligand-based approach for predicting drug targets and for virtual screening against COVID-19

Authors : Cheng Peng; Weiliang Zhu; Yulong Shi

Subjects: 0301 basic medicine; Drug; AcademicSubjects/SCI01060

Source: Briefings in Bioinformatics

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Bioinformatics helping to mitigate the impact of COVID-19 – Editorial

Authors : Mario Cannataro; Andrew Harrison

Subjects: 2019-20 coronavirus outbreak; AcademicSubjects/SCI01060; Coronavirus disease 2019 (COVID-19)

Source: Briefings in Bioinformatics

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Synthetic directed evolution in plants: unlocking trait engineering and improvement

Authors : Wenjun Jiang; Gundra Sivakrishna Rao; Magdy M. Mahfouz

Subjects: AcademicSubjects/SCI01060; Computer science; Emerging technologies

Source: Synthetic Biology

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A CRISPR/Cas9 method facilitates efficient oligo-mediated gene editing in Debaryomyces hansenii

Authors : Tomas Strucko; Niklas L Andersen; Mikkel R. Mahler

Subjects: AcademicSubjects/SCI01060; AcademicSubjects/SCI02299; CUG clade

Source: Synthetic BiologyStrucko, T, Andersen, N L, Mahler, M R, Martínez, J L & Mortensen, U H 2021, ' A CRISPR/Cas9 Method Facilitates Efficient Oligo-Mediated Gene Editing in Debaryomyces Hansenii

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RefRGim: an intelligent reference panel reconstruction method for genotype imputation with convolutional neural networks

Authors : Jingyao Zeng; Qiheng Qian; Zhenglin Du

Subjects: AcademicSubjects/SCI01060; Genotype; Genotyping Techniques

Source: Briefings in Bioinformatics

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Rational gRNA design based on transcription factor binding data

Authors : Jens Nielsen; Yasaman Dabirian; Florian David

Subjects: gRNA design; AcademicSubjects/SCI01060; AcademicSubjects/SCI02299

Source: Synthetic Biology

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Consensus clustering of single-cell RNA-seq data by enhancing network affinity

Authors : Shaoqiang Zhang; Thomas N. Ferraro; Yaxuan Cui

Subjects: AcademicSubjects/SCI01060; Computer science; Cell

Source: Briefings in Bioinformatics

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LSTM-PHV: prediction of human-virus protein–protein interactions by LSTM with word2vec

Authors : Md. Mehedi Hasan; Hiroyuki Kurata; Sho Tsukiyama

Subjects: AcademicSubjects/SCI01060; Computer science; Computational biology

Source: Briefings in Bioinformatics

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