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  • 1-10 ل  2,549 نتائج ل ""CHECKPOINT kinase 1""
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Academic Journal

RBM17 Promotes the Chemoresistance of Oral Squamous Cancer Cells Through Checkpoint Kinase 1.

  • Authors : Nakahara M; Department of Oral and Maxillofacial Surgery, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.; Arai R

Subjects: Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/genetics ; Mouth Neoplasms*/Mouth Neoplasms*/Mouth Neoplasms*/metabolism ; Mouth Neoplasms*/Mouth Neoplasms*/Mouth Neoplasms*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Mar 28; Vol. 26 (7). Date of Electronic Publication: 2025 Mar 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasis.

  • Authors : Thakur V; Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, Miami, FL, 33136, USA.; Thakur VS

Subjects: Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/antagonists & inhibitors ; Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/metabolism ; Receptor, Notch1*/Receptor, Notch1*/Receptor, Notch1*/antagonists & inhibitors

  • Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2025 May 28; Vol. 44 (1), pp. 163. Date of Electronic Publication: Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Academic Journal

Predicting breast cancer prognosis based on a novel pathomics model through CHEK1 expression analysis using machine learning algorithms.

  • Authors : Chen C; Breast and Thyroid Center, The First People's Hospital of Zunyi (The Third Affiliated Hospital of Zunyi Medical University), Zunyi, Guizhou, China.; Gao D

Subjects: Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/genetics ; Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/metabolism ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics

  • Source: PloS one [PLoS One] 2025 May 09; Vol. 20 (5), pp. e0321717. Date of Electronic Publication: 2025 May 09 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Cancer Vulnerabilities Through Targeting the ATR/Chk1 and ATM/Chk2 Axes in the Context of DNA Damage.

  • Authors : Fernandez A; Program in Solid Tumors, CIMA, Cancer Center Clinica Universidad de Navarra (CCUN), University of Navarra, Avenida de Pio XII, 55, 31008 Pamplona, Spain.; Department of Pathology, Anatomy and Physiology, School of Medicine, University of Navarra, 31008 Pamplona, Spain.

Subjects: DNA Damage* ; Checkpoint Kinase 2*/Checkpoint Kinase 2*/Checkpoint Kinase 2*/metabolism ; Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/metabolism

  • Source: Cells [Cells] 2025 May 20; Vol. 14 (10). Date of Electronic Publication: 2025 May 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Checkpoint kinases regulate the circadian clock after DNA damage by influencing chromatin dynamics.

  • Authors : Yang Y; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of the Chinese Academy of Sciences, Beijing 100049, China.

Subjects: DNA Damage* ; Neurospora crassa*/Neurospora crassa*/Neurospora crassa*/genetics ; Neurospora crassa*/Neurospora crassa*/Neurospora crassa*/metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Feb 27; Vol. 53 (5).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Exosomes derived from hUC-MSCs exhibit ameliorative efficacy upon previous cesarean scar defect via orchestrating β-TrCP/CHK1 axis.

  • Authors : Zeng X; Department of Obstetrics, Guizhou Provincial People's Hospital, Guiyang, 550001, Guizhou, China.; Liao Y

Subjects: Exosomes*/Exosomes*/Exosomes*/metabolism ; Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Jan 02; Vol. 15 (1), pp. 489. Date of Electronic Publication: 2025 Jan 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Interaction of DDB1 with NBS1 in a DNA Damage Checkpoint Pathway.

  • Authors : Lim HE; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, Republic of Korea.; Research Institute for Future Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea.

Subjects: Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/genetics ; DNA Damage*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 05; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Inhibition of Chk1 with Prexasertib Enhances the Anticancer Activity of Ciclopirox in Non-Small Cell Lung Cancer Cells.

  • Authors : Huang Z; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.; Collaborative Innovation Center of Targeted Development of Medicinal Resources, College of Life Science, Anqing Normal University, Anqing 246011, Anhui, China.

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism

  • Source: Cells [Cells] 2024 Oct 23; Vol. 13 (21). Date of Electronic Publication: 2024 Oct 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Correlation between Molecular Docking and the Stabilizing Interaction of HOMO-LUMO: Spirostans in CHK1 and CHK2, an In Silico Cancer Approach.

Subjects: Molecular Docking Simulation* ; Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/metabolism ; Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 06; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo.

  • Authors : Baran V; Institute of Animal Physiology, Centre of Biosciences, Slovak Academy of Sciences, Šoltésovej 4, 040 00 Košice, Slovakia.; Mayer A

Subjects: Checkpoint Kinase 1*/Checkpoint Kinase 1*/Checkpoint Kinase 1*/metabolism ; DNA Damage* ; Embryonic Development*/Embryonic Development*/Embryonic Development*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 05; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 ل  2,549 نتائج ل ""CHECKPOINT kinase 1""