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A formulation strategy for solving the overgranulation problem in high shear wet granulation.

• Authors : Osei-Yeboah F; Pharmaceutical Materials Science and Engineering Laboratory, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, 55455.; Zhang M

Subjects: Calcium Phosphates/Calcium Phosphates/Calcium Phosphates/*chemistry ; Cellulose/Cellulose/Cellulose/*chemistry ; Excipients/Excipients/Excipients/*chemistry

• Source: Journal of pharmaceutical sciences [J Pharm Sci] 2014 Aug; Vol. 103 (8), pp. 2434-40. Date of Electronic Publication: 2014 Jul 01.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The effect of the physical state of binders on high-shear wet granulation and granule properties: a mechanistic approach to understand the high-shear wet granulation process. part IV. the impact of rheological state and tip-speeds.

• Authors : Li J; Drug Product Science & Technology, Bristol-Myers Squibb, New Brunswick, New Jersey, 08901.; Tao L

Subjects: Drug Compounding*/Drug Compounding*/Drug Compounding*/methods; Cellulose/Cellulose/Cellulose/*analogs & derivatives ; Excipients/Excipients/Excipients/*chemistry

• Source: Journal of pharmaceutical sciences [J Pharm Sci] 2013 Dec; Vol. 102 (12), pp. 4384-94. Date of Electronic Publication: 2013 Oct 17.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Evolution of structure and properties of granules containing microcrystalline cellulose and polyvinylpyrrolidone during high-shear wet granulation.

• Authors : Osei-Yeboah F; Pharmaceutical Materials Science and Engineering Laboratory, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, 55455.; Feng Y

Subjects: Cellulose/Cellulose/Cellulose/*chemistry ; Povidone/Povidone/Povidone/*chemistry; Particle Size

• Source: Journal of pharmaceutical sciences [J Pharm Sci] 2014 Jan; Vol. 103 (1), pp. 207-15. Date of Electronic Publication: 2013 Nov 11.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Microstructure of micro-crystalline cellulose based granules produced by high-shear wet granulation with long wet-massing time.

• Authors : Farber, Leon¹ ; Michaels, James N.²

• Source: Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A. Apr2018, Vol. 132, p1054-1059. 6p.

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Roles of granule size in over-granulation during high shear wet granulation.

• Authors : Limin Shi¹; Yushi Feng²; Changquan Calvin Sun¹

Subjects: *CYTOPLASMIC granules; *GRANULATION; *MICROCRYSTALLINE polymers

• Source: Journal of Pharmaceutical Sciences. Aug2010, Vol. 99 Issue 8, p3322-3325. 4p. 4 Graphs.

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Evaluating Scale-Up Rules of a High-Shear Wet Granulation Process.

• Authors : Tao, Jing¹; Pandey, Preetanshu¹; Bindra, Dilbir S.¹

Subjects: *DRUG granulation; *CELLULOSE; *LACTOSE

• Source: Journal of Pharmaceutical Sciences. Jul2015, Vol. 104 Issue 7, p2323-2333. 11p. 6 Charts, 9 Graphs.

تفاصيل العنوان

Microstructure of micro-crystalline cellulose based granules produced by high-shear wet granulation with long wet-massing time

• Authors : James N. Michaels; Leon Farber

Subjects: Materials science; General Chemical Engineering; Granule (cell biology)

• Source: Chemical Engineering Research and Design. 132:1054-1059

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Real-Time Assessment of Granule Densification in High Shear Wet Granulation and Application to Scale-up of a Placebo and a Brivanib Alaninate Formulation

• Authors : Sherif Badawy; Ajit S. Narang; Valery Sheverev

Subjects: Quality Control; Materials science; Mass Consistency

• Source: Journal of Pharmaceutical Sciences. 104:1019-1034

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A Formulation Strategy for Solving the Overgranulation Problem in High Shear Wet Granulation

• Authors : Changquan Calvin Sun; Minglun Zhang; Yushi Feng

Subjects: Calcium Phosphates; Materials science; Scanning electron microscope

• Source: Journal of Pharmaceutical Sciences. 103:2434-2440

تفاصيل العنوان

The Effect of the Physical State of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach to Understand the High-Shear Wet Granulation Process. Part IV. The Impact of Rheological State and Tip-speeds

• Authors : Mario Hubert; David Buckley; Jinjiang Li

Subjects: Materials science; Viscosity; Drug Compounding

• Source: Journal of Pharmaceutical Sciences. 102:4384-4394

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