نتائج البحث

CHD1L Regulates Cell Survival in Breast Cancer and Its Inhibition by OTI-611 Impedes the DNA Damage Response and Induces PARthanatos.

• Authors : Sala R; Department of Pharmaceutical Sciences, The Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO 80045, USA.; Esquer H

Subjects: DNA Damage*/DNA Damage*/DNA Damage*/drug effects ; DNA Helicases*/DNA Helicases*/DNA Helicases*/metabolism ; DNA Helicases*/DNA Helicases*/DNA Helicases*/genetics

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 06; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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The In Vitro Enhancement of Retinal Cell Viability via m 6 A and m 5 C RNA Methylation-Mediated Changes in the Levels of Heme Oxygenase (HO-1) and DNA Damage Repair Molecules Using a 50 Hz Sinusoidal Electromagnetic Field (EMF).

• Authors : Betlej G; Interdisciplinary Centre for Preclinical and Clinical Research, College of Natural Sciences, University of Rzeszow, Werynia 2a, 36-100 Kolbuszowa, Poland.; Bator E

Subjects: Cell Survival*/Cell Survival*/Cell Survival*/radiation effects ; Adenosine*/Adenosine*/Adenosine*/analogs & derivatives ; Adenosine*/Adenosine*/Adenosine*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 19; Vol. 25 (24). Date of Electronic Publication: 2024 Dec 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Ionization Detail Parameters for DNA Damage Evaluation in Charged Particle Radiotherapy: Simulation Study Based on Cell Survival Database.

• Authors : Mietelska M; Biomedical Physics Division, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.; Radiological Metrology and Biomedical Physics Division, Nuclear Facilities Operations Department, National Centre for Nuclear Research, 05-400 Świerk, Poland.

Subjects: DNA Damage* ; Monte Carlo Method* ; Cell Survival*/Cell Survival*/Cell Survival*/radiation effects

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 07; Vol. 25 (10). Date of Electronic Publication: 2024 May 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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DNA damage-induced YTHDC1 O-GlcNAcylation promotes homologous recombination by enhancing m6A binding.

• Authors : Mengyao Li¹; Jie Li²; Yibo Wang³

• Source: Fundamental Research. Mar2025, Vol. 5 Issue 2, p868-879. 12p.

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Assessment of the toxicity of different antiretroviral drugs and their combinations on Sertoli and Leydig cells.

• Authors : Baysal M; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.; Karaduman AB

Subjects: Sertoli Cells*/Sertoli Cells*/Sertoli Cells*/drug effects ; Sertoli Cells*/Sertoli Cells*/Sertoli Cells*/metabolism ; Reactive Oxygen Species*/Reactive Oxygen Species*/Reactive Oxygen Species*/metabolism

• Source: Drug and chemical toxicology [Drug Chem Toxicol] 2024 Nov; Vol. 47 (6), pp. 1100-1108. Date of Electronic Publication: 2024 Apr 22.Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 7801723 Publication Model: Print-Electronic Cited Medium: Internet

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Cytotoxic, Antioxidant, and Anti-Genotoxic Properties of Combretastatin A4 in Human Peripheral Blood Mononuclear Cells: A Comprehensive In Vitro Study.

• Authors : Popović P; Department of Pathobiology, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.; Pirković A

Subjects: Leukocytes, Mononuclear*/Leukocytes, Mononuclear*/Leukocytes, Mononuclear*/drug effects ; Leukocytes, Mononuclear*/Leukocytes, Mononuclear*/Leukocytes, Mononuclear*/metabolism ; Antioxidants*/Antioxidants*/Antioxidants*/pharmacology

• Source: Biomolecules [Biomolecules] 2024 Nov 30; Vol. 14 (12). Date of Electronic Publication: 2024 Nov 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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The ameliorative effect of rosmarinic acid and epigallocatechin gallate against doxorubicin-induced genotoxicity.

• Authors : Helvacioglu S; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, İstinye University, Istanbul, Turkey.; Charehsaz M

Subjects: Rosmarinic Acid* ; Catechin*/Catechin*/Catechin*/analogs & derivatives ; Catechin*/Catechin*/Catechin*/pharmacology

• Source: Drug and chemical toxicology [Drug Chem Toxicol] 2024 Nov; Vol. 47 (6), pp. 1087-1099. Date of Electronic Publication: 2024 Mar 26.Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 7801723 Publication Model: Print-Electronic Cited Medium: Internet

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In vitro evaluation of the selective cytotoxicity and genotoxicity of three synthetic ortho -nitrobenzyl derivatives in human cancer cell lines, with and without metabolic activation.

• Authors : Teixeira De Oliveira J; Laboratório de Biologia Celular e Mutagênese (LaBCeM), Universidade Federal de São João del Rei (UFSJ), Divinópolis, Brazil.; Núcleo de Pesquisa em Química Biológica (NQBio), Universidade Federal de São João del Rei (UFSJ), Divinópolis, Brazil.

Subjects: Cell Survival*/Cell Survival*/Cell Survival*/drug effects ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/toxicity ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

• Source: Drug and chemical toxicology [Drug Chem Toxicol] 2024 Jul; Vol. 47 (4), pp. 404-415. Date of Electronic Publication: 2023 Mar 08.Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 7801723 Publication Model: Print-Electronic Cited Medium: Internet

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The Impact of Oleuropein on Cisplatin-Induced Toxicity in Cochlear Cells in Relation to the Expression of Deoxyribonucleic Acid Damage-Associated Genes.

• Authors : Olgun Y; Department of Otorhinolaryngology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.; Altun Z

Subjects: Cisplatin*/Cisplatin*/Cisplatin*/toxicity ; Iridoid Glucosides*/Iridoid Glucosides*/Iridoid Glucosides*/pharmacology ; DNA Damage*/DNA Damage*/DNA Damage*/drug effects

• Source: The journal of international advanced otology [J Int Adv Otol] 2024 May 23; Vol. 20 (3), pp. 189-195.Publisher: AVES Country of Publication: Turkey NLM ID: 101522982 Publication Model: Print Cited Medium: Internet ISSN: 2148-3817 (Electronic)

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STIM1 translocation to the nucleus protects cells from DNA damage.

• Authors : Sanchez-Lopez, Irene^1,2 (AUTHOR); Orantos-Aguilera, Yolanda^1,2 (AUTHOR); Pozo-Guisado, Eulalia^2,3 (AUTHOR)

Subjects: *DNA repair; *DNA damage; *CELL nuclei

• Source: Nucleic Acids Research. 3/21/2024, Vol. 52 Issue 5, p2389-2415. 27p.

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