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Antiproliferative Fate of the Tetraploid Formed after Mitotic Slippage and Its Promotion; A Novel Target for Cancer Therapy Based on Microtubule Poisons.

• Authors : Nakayama Y; Division of Functional Genomics, Research Center for Bioscience and Technology, Tottori University, 86 Nishi-cho, Yonago, Tottori 683-8503, Japan. .; Inoue T

Subjects: Tetraploidy*; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects ; Microtubules/Microtubules/Microtubules/*drug effects

• Source: Molecules (Basel, Switzerland) [Molecules] 2016 May 19; Vol. 21 (5). Date of Electronic Publication: 2016 May 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Combination Treatment of OSI-906 with Aurora B Inhibitor Reduces Cell Viability via Cyclin B1 Degradation-Induced Mitotic Slippage

• Authors : Yuji Nakayama; Youhei Saito; Ryuzaburo Yuki

Subjects: Lung Neoplasms; Cell division; linsitinib

• Source: International Journal of Molecular Sciences, Vol 22, Iss 5706, p 5706 (2021)International Journal of Molecular SciencesVolume 22Issue 11

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The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1

• Authors : Maiko Nagano; Yuji Nakayama; Youhei Saito

Subjects: 0301 basic medicine; Paclitaxel; Mitosis

• Source: Journal of Biological Chemistry. 293:15524-15537

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'Mitotic Slippage' and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres

• Authors : Inna Inashkina; Jekaterina Erenpreisa; Ninel M. Vainshelbaum ...

Subjects: Polyploidization; ALT; SQSTM1/p62

• Source: International Journal of Molecular SciencesVolume 21Issue 8International Journal of Molecular Sciences, Vol 21, Iss 2779, p 2779 (2020)Digital.CSIC. Repositorio Institucional

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Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53

• Authors : Masahiko Shibazaki; Chihaya Maesawa; Masao Nishiya

Subjects: 0301 basic medicine; Cell cycle checkpoint; Paclitaxel

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Mitotic slippage and the subsequent cell fates after inhibition of Aurora B during tubulin-binding agent–induced mitotic arrest

• Authors : Koji Ando; Yuichiro Nakashima; Ryota Nakanishi

Subjects: 0301 basic medicine; Paclitaxel; Cell Survival

• Source: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)Scientific Reports

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Mitotic slippage and expression of survivin are linked to differential sensitivity of human cancer cell-lines to the Kinesin-5 inhibitor monastrol

• Authors : Hila Asraf; Rachel Avunie-Masala; Larisa Gheber

Subjects: Small interfering RNA; Survivin; Blotting, Western

• Source: PLoS ONE, Vol 10, Iss 6, p e0129255 (2015)PLoS ONE

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Inactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic Slippage

• Authors : Marta Cagigas; Ernesto de Diego; Pilar Alonso-Lecue

Subjects: DNA Replication; Keratinocytes; Male

• Source: Cell Reports, Vol 9, Iss 4, Pp 1349-1360 (2014)

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Inhibition of Bcl-xL overcomes polyploidy resistance and leads to apoptotic cell death in acute myeloid leukemia cells

• Authors : Bin Wang; Anwen Liu; Weihua Zhou

Subjects: Indoles; Cell Survival; medicine.medical_treatment

• Source: Oncotarget

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Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivo

• Authors : Piyush Trivedi; Chandrabose Karthikeyan; Mohd Rais Mustafa

Subjects: 0301 basic medicine; Pathology; Survivin

• Source: Oncotarget

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