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Flavonoid chrysin activates both TrkB and FGFR1 receptors while upregulates their endogenous ligands such as brain derived neurotrophic factor to promote human neurogenesis.

• Authors : Dong X; School of Life Science and Technology, Shanghai Tech University, Shanghai, China.; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.

Subjects: Flavonoids*/Flavonoids*/Flavonoids*/pharmacology ; Neurogenesis*/Neurogenesis*/Neurogenesis*/drug effects ; Receptor, Fibroblast Growth Factor, Type 1*/Receptor, Fibroblast Growth Factor, Type 1*/Receptor, Fibroblast Growth Factor, Type 1*/metabolism

• Source: Cell proliferation [Cell Prolif] 2025 Jan; Vol. 58 (1), pp. e13732. Date of Electronic Publication: 2024 Sep 27.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell

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RAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma.

• Authors : Jermakowicz AM; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA.; Kurimchak AM

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology

• Source: Scientific reports [Sci Rep] 2024 Apr 23; Vol. 14 (1), pp. 9284. Date of Electronic Publication: 2024 Apr 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1.

• Authors : Opaliński Ł; Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383 Wroclaw, Poland. .; Szymczyk J

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*pharmacology ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects ; Neoplasms/Neoplasms/Neoplasms/*drug therapy

• Source: International journal of molecular sciences [Int J Mol Sci] 2018 May 10; Vol. 19 (5). Date of Electronic Publication: 2018 May 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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TNFAIP3 is required for FGFR1 activation-promoted proliferation and tumorigenesis of premalignant DCIS.COM human mammary epithelial cells

• Authors : Mao Yang; Xiaobin Yu; Xuesen Li

Subjects: Breast cancer; FGFR1; Gene regulation

• Source: Breast Cancer Research, Vol 20, Iss 1, Pp 1-14 (2018)

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Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities.

• Authors : Ren M; Georgia Health Sciences University, Cancer Center, Augusta, GA 30912, USA.; Qin H

Subjects: Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects ; Imidazoles/Imidazoles/Imidazoles/*therapeutic use ; Leukemia, Promyelocytic, Acute/Leukemia, Promyelocytic, Acute/Leukemia, Promyelocytic, Acute/*mortality

• Source: Leukemia [Leukemia] 2013 Jan; Vol. 27 (1), pp. 32-40. Date of Electronic Publication: 2012 Jul 11.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Brassinin Promotes the Degradation of Tie2 and FGFR1 in Endothelial Cells and Inhibits Triple-Negative Breast Cancer Angiogenesis.

• Authors : Gu, Yuan¹ (AUTHOR) ; Becker, Vivien¹ (AUTHOR) ; Qiu, Moqin^1,2 (AUTHOR)

• Source: Cancers. Jul2022, Vol. 14 Issue 14, pN.PAG-N.PAG. 18p.

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circITGA7 Functions as an Oncogene by Sponging miR-198 and Upregulating FGFR1 Expression in Thyroid Cancer.

• Authors : Li, Siqi¹ (AUTHOR); Yang, Junmei¹ (AUTHOR); Liu, Xiaoting¹ (AUTHOR)

• Source: BioMed Research International. 6/22/2020, p1-8. 8p.

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Fibroblast growth factor receptor 1 protein (FGFR1) as potential prognostic and predictive marker in patients with luminal B breast cancers overexpressing human epidermal receptor 2 protein (HER2)

• Authors : Belhadj, Amina; Addou Klouche, Lynda; Seddiki, Sonia

Subjects: Adult; Aged, 80 and over; Receptor, ErbB-2

• Source: Indian Journal of Pathology and Microbiology, Vol 64, Iss 2, Pp 254-260 (2021)

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Anlotinib can overcome acquired resistance to EGFR‐TKIs via FGFR1 signaling in non‐small cell lung cancer without harboring EGFR T790M mutation

• Authors : Yulong Fu; Yang Zhang; Tingting Cai

Subjects: 0301 basic medicine; Indoles; Lung Neoplasms

• Source: Thoracic Cancer, Vol 11, Iss 7, Pp 1934-1943 (2020)Thoracic Cancer

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Dihydroartemisinin targets fibroblast growth factor receptor 1 (FGFR1) to inhibit interleukin 17A (IL-17A)-induced hyperproliferation and inflammation of keratinocytes

• Authors : Baojiang Chen; Chen Li; Guizhen Chang

Subjects: Keratinocytes; Cell Survival; Anti-Inflammatory Agents

• Source: Bioengineeredarticle-version (VoR) Version of RecordBioengineered, Vol 13, Iss 1, Pp 1530-1540 (2022)

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