Authors : Huang Z; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.; Collaborative Innovation Center of Targeted Development of Medicinal Resources, College of Life Science, Anqing Normal University, Anqing 246011, Anhui, China.

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism

Source: Cells [Cells] 2024 Oct 23; Vol. 13 (21). Date of Electronic Publication: 2024 Oct 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Checkpoint Kinase 1 Stimulates Endogenous Cardiomyocyte Renewal and Cardiac Repair by Binding to Pyruvate Kinase Isoform M2 C‐Domain and Activating Cardiac Metabolic Reprogramming in a Porcine Model of Myocardial Ischemia/Reperfusion Injury

Authors : Tian‐Wen Wei; Tian‐Kai Shan; Hao Wang

Subjects: Thyroid Hormones; Swine; Pyruvate Kinase

Source: J Am Heart AssocJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 13 (2024)

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Phosphoproteomic Analysis of Neonatal Regenerative Myocardium Revealed Important Roles of Checkpoint Kinase 1 via Activating Mammalian Target of Rapamycin C1/Ribosomal Protein S6 Kinase b-1 Pathway

Authors : Yi Fan; Yiwei Cheng; Yafei Li

Subjects: 0301 basic medicine; Mice, Inbred ICR; Proteome

Source: Circulation. 141:1554-1569

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Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway.

Authors : Song L; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China.

Subjects: Apoptosis* ; Cell Cycle Checkpoints* ; Cell Proliferation*

Source: Virology journal [Virol J] 2018 Nov 06; Vol. 15 (1), pp. 169. Date of Electronic Publication: 2018 Nov 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X

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The aberrant upstream pathway regulations of CDK1 protein were implicated in the proliferation and apoptosis of ovarian cancer cells.

Authors : Zhang R; Department of Gynecology, First Affiliated Hospital, Zhengzhou University, NO.1 Jianshe Road, Zhengzhou, 450052, Henan, People's Republic of China. .; Shi H

Subjects: Apoptosis* ; Cell Proliferation*; CDC2 Protein Kinase/CDC2 Protein Kinase/CDC2 Protein Kinase/*metabolism

Source: Journal of ovarian research [J Ovarian Res] 2017 Sep 12; Vol. 10 (1), pp. 60. Date of Electronic Publication: 2017 Sep 12.Publisher: BioMed Central Country of Publication: England NLM ID: 101474849 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-2215

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Checkpoint Kinase 1 Pharmacological Inhibition Synergizes with DNA-Damaging Agents and Overcomes Platinum Resistance in Basal-Like Breast Cancer

Authors : Cristina Nieto-Jimenez; Ana Alcaraz-Sanabria; Sandra Martinez-Canales ...

Subjects: chemotherapy resistance; Synthetic lethality; platinum compounds

Source: Int J Mol SciDigital.CSIC. Repositorio Institucional del CSICinstnameRepositorio Institucional de la Consejería de Sanidad de la Comunidad de MadridConsejería de Sanidad de

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Disruption of spindle checkpoint function ahead of facilitation of cell proliferation by repeated administration of hepatocarcinogens in rats.

Authors : Kimura M; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology.; Mizukami S

Subjects: Carbadox/Carbadox/Carbadox/*toxicity ; Carcinogens/Carcinogens/Carcinogens/*administration & dosage ; Carcinogens/Carcinogens/Carcinogens/*toxicity

Source: The Journal of toxicological sciences [J Toxicol Sci] 2015 Dec; Vol. 40 (6), pp. 855-71.Publisher: Doku Sayō Kenkyūkai Country of Publication: Japan NLM ID: 7805798 Publication Model: Print Cited Medium: Internet ISSN: 1880-3989

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Apogossypolone induces reactive oxygen species accumulation and controls cell cycle progression in Raji Burkkit's lymphoma cells.

Authors : Hu ZY; Sun Yat‑sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, P.R. China.; Xu F

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects ; Gossypol/Gossypol/Gossypol/*analogs & derivatives

Source: Molecular medicine reports [Mol Med Rep] 2015 Jul; Vol. 12 (1), pp. 337-44. Date of Electronic Publication: 2015 Mar 03.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Autoregulatory Mechanisms of Phosphorylation of Checkpoint Kinase 1

Authors : Youwei Zhang; Jingna Wang; Xiangzi Han

Subjects: Cell Cycle Proteins; Ataxia Telangiectasia Mutated Proteins; Protein Serine-Threonine Kinases

Source: Cancer Research. 72:3786-3794

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Context Dependence of Checkpoint Kinase 1 as a Therapeutic Target for Pancreatic Cancers Deficient in the BRCA2 Tumor Suppressor

Authors : Ashok R. Venkitaraman; Hiroyoshi Hattori; Paul Russell

Subjects: BRCA2 Protein; 0301 basic medicine; Tumor Suppressor Proteins

Source: Molecular Cancer Therapeutics. 10:670-678

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فلترة النتائج

Inhibition of Chk1 with Prexasertib Enhances the Anticancer Activity of Ciclopirox in Non-Small Cell Lung Cancer Cells.

Checkpoint Kinase 1 Stimulates Endogenous Cardiomyocyte Renewal and Cardiac Repair by Binding to Pyruvate Kinase Isoform M2 C‐Domain and Activating Cardiac Metabolic Reprogramming in a Porcine Model of Myocardial Ischemia/Reperfusion Injury

Phosphoproteomic Analysis of Neonatal Regenerative Myocardium Revealed Important Roles of Checkpoint Kinase 1 via Activating Mammalian Target of Rapamycin C1/Ribosomal Protein S6 Kinase b-1 Pathway

Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway.

The aberrant upstream pathway regulations of CDK1 protein were implicated in the proliferation and apoptosis of ovarian cancer cells.

Checkpoint Kinase 1 Pharmacological Inhibition Synergizes with DNA-Damaging Agents and Overcomes Platinum Resistance in Basal-Like Breast Cancer

Disruption of spindle checkpoint function ahead of facilitation of cell proliferation by repeated administration of hepatocarcinogens in rats.

Apogossypolone induces reactive oxygen species accumulation and controls cell cycle progression in Raji Burkkit's lymphoma cells.

Autoregulatory Mechanisms of Phosphorylation of Checkpoint Kinase 1

Context Dependence of Checkpoint Kinase 1 as a Therapeutic Target for Pancreatic Cancers Deficient in the BRCA2 Tumor Suppressor

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