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Academic Journal

Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies

Authors : Yee, Sook Wah; Buitrago, Dina; Stecula, Adrian

Subjects: Biological Sciences; Biomedical and Clinical Sciences; Genetics

Source: The FASEB Journal. 34(12)

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Academic Journal

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

Authors : Miner, Jeffrey N; Tan, Philip K; Hyndman, David

Subjects: Pharmacology and Pharmaceutical Sciences; Biomedical and Clinical Sciences; Complementary and Integrative Health

Source: Arthritis Research & Therapy. 18(1)

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Academic Journal

The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers

Authors : Morrissey, Kari M; Stocker, Sophie L; Chen, Eugene C

Subjects: Pharmacology and Pharmaceutical Sciences; Biomedical and Clinical Sciences; Clinical Sciences

Source: Clinical Pharmacokinetics. 55(4)

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Academic Journal

Targeted Disruption of Organic Cation Transporter 3 Attenuates the Pharmacologic Response to Metformin

Authors : Chen, Eugene C; Liang, Xiaomin; Yee, Sook Wah

Subjects: Pharmacology and Pharmaceutical Sciences; Biomedical and Clinical Sciences; Diabetes

Source: Molecular Pharmacology. 88(1)

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Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury

Authors : Wei-Yi Ong; Samantha Chia Yi Ooi; Sally Shuxian Koh

Subjects: 0301 basic medicine; Necrosis; Mushrooms

Source: NeuroMolecular MedicineNeuromolecular Medicine

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Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein‐Mediated Drug‐Drug Interactions in Healthy Volunteers

Authors : Lauren Horlbogen; Vu Le; Hiroyuki Kusuhara

Subjects: Drug; Adult; Male

Source: Clinical Pharmacology and Therapeutics

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A Systematic In Vitro Investigation of the Inhibitor Preincubation Effect on Multiple Classes of Clinically Relevant Transporters

Authors : Felix Huth; Birk Poller; Imad Hanna

Subjects: Pharmacology; Drug; Organic cation transport proteins

Source: Drug Metabolism and Disposition. 47:768-778

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In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs

Authors : Edgar A. Jaimes; Lauren M. Aleksunes; Xia Wen

Subjects: 0301 basic medicine; Gene Expression; Pharmacology

Source: International Journal of Molecular SciencesVolume 22Issue 12International Journal of Molecular Sciences, Vol 22, Iss 6439, p 6439 (2021)

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Enhanced expression of Organic Cation Transporters in bronchial epithelial cell layers following insults associated with asthma – Impact on salbutamol transport

Authors : Manali Mukherjee; David I. Pritchard; Cynthia Bosquillon

Subjects: Lipopolysaccharides; 0301 basic medicine; Airway epithelium

Source: European Journal of Pharmaceutical Sciences. 106:62-70

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Multiple drug transporters mediate the placental transport of sulpiride

Authors : Caihong Zheng; Huidi Jiang; Mengru Bai

Subjects: 0301 basic medicine; medicine.medical_specialty; ATP Binding Cassette Transporter, Subfamily B

Source: Archives of Toxicology. 91:3873-3884

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فلترة النتائج

Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers

Targeted Disruption of Organic Cation Transporter 3 Attenuates the Pharmacologic Response to Metformin

Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury

Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein‐Mediated Drug‐Drug Interactions in Healthy Volunteers

A Systematic In Vitro Investigation of the Inhibitor Preincubation Effect on Multiple Classes of Clinically Relevant Transporters

In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs

Enhanced expression of Organic Cation Transporters in bronchial epithelial cell layers following insults associated with asthma – Impact on salbutamol transport

Multiple drug transporters mediate the placental transport of sulpiride

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