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Academic Journal

Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats.

Authors : Li X; State Key Laboratory of Agro-Biotechnology and Beijing Advanced Innovation Center for Food Nutrition and Human Health, MOA Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing, P.R. China.; Jin X

Subjects: Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Gene Expression Regulation, Fungal/Gene Expression Regulation, Fungal/Gene Expression Regulation, Fungal/*physiology ; Glycogen Synthase Kinase 3/Glycogen Synthase Kinase 3/Glycogen Synthase Kinase 3/*metabolism

Source: PLoS genetics [PLoS Genet] 2019 Aug 05; Vol. 15 (8), pp. e1008136. Date of Electronic Publication: 2019 Aug 05 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Exceptional origin activation revealed by comparative analysis in two laboratory yeast strains.

Authors : Joshi I; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York, United States of America.; Peng J

Subjects: Replication Origin*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics ; Checkpoint Kinase 2/Checkpoint Kinase 2/Checkpoint Kinase 2/*genetics

Source: PloS one [PLoS One] 2022 Feb 14; Vol. 17 (2), pp. e0263569. Date of Electronic Publication: 2022 Feb 14 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Exo1 phosphorylation inhibits exonuclease activity and prevents fork collapse in rad53 mutants independently of the 14-3-3 proteins.

Authors : Morafraile EC; Instituto de Biología Funcional y Genómica (CSIC/USAL), Campus Miguel de Unamuno, Salamanca 37007, Spain.; Bugallo A

Subjects: 14-3-3 Proteins/14-3-3 Proteins/14-3-3 Proteins/*genetics ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics ; Checkpoint Kinase 2/Checkpoint Kinase 2/Checkpoint Kinase 2/*genetics

Source: Nucleic acids research [Nucleic Acids Res] 2020 Apr 06; Vol. 48 (6), pp. 3053-3070.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Therapeutic Co-targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer.

Authors : Jin MH; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.; Nam AR

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/*antagonists & inhibitors ; B7-H1 Antigen/B7-H1 Antigen/B7-H1 Antigen/*genetics

Source: Cancer research and treatment [Cancer Res Treat] 2020 Jan; Vol. 52 (1), pp. 149-166. Date of Electronic Publication: 2019 Jun 25.Publisher: Korean Cancer Association Country of Publication: Korea (South) NLM ID: 101155137 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Ddc2ATRIP promotes Mec1ATR activation at RPA-ssDNA tracts.

Authors : Biswas H; Department of Microbiology, Biochemistry and Molecular Genetics, International Center for Public Health, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, United States of America.; Goto G

Subjects: DNA Repair*; Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism

Source: PLoS genetics [PLoS Genet] 2019 Aug 01; Vol. 15 (8), pp. e1008294. Date of Electronic Publication: 2019 Aug 01 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

DNA replication checkpoint signaling depends on a Rad53-Dbf4 N-terminal interaction in Saccharomyces cerevisiae.

Authors : Chen YC; Laboratory of Genome Integrity and Tumorigenesis, Van Andel Research Institute, Grand Rapids, MI 49503, USA.; Kenworthy J

Subjects: DNA Replication* ; S Phase Cell Cycle Checkpoints* ; Signal Transduction*

Source: Genetics [Genetics] 2013 Jun; Vol. 194 (2), pp. 389-401. Date of Electronic Publication: 2013 Apr 05.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A prolyl-hydroxylase inhibitor, ethyl-3,4-dihydroxybenzoate, induces cell autophagy and apoptosis in esophageal squamous cell carcinoma cells via up-regulation of BNIP3 and N-myc downstream-regulated gene-1.

Authors : Han B; State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; Li W

Subjects: Apoptosis/Apoptosis/Apoptosis/*genetics ; Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/*drug therapy ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics

Source: PloS one [PLoS One] 2014 Sep 18; Vol. 9 (9), pp. e107204. Date of Electronic Publication: 2014 Sep 18 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1.

Authors : Nielsen I; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Bentsen IB

Subjects: Genome, Fungal*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Checkpoint Kinase 2/Checkpoint Kinase 2/Checkpoint Kinase 2/*metabolism

Source: PloS one [PLoS One] 2013 Nov 20; Vol. 8 (11), pp. e81015. Date of Electronic Publication: 2013 Nov 20 (Print Publication: 2013).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Impact of heterozygous c.657-661del, p.I171V and p.R215W mutations in NBN on nibrin functions.

Authors : Dzikiewicz-Krawczyk A; Department of Molecular Pathology, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland. ; Mosor M

Subjects: Mutation, Missense* ; Sequence Deletion*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics

Source: Mutagenesis [Mutagenesis] 2012 May; Vol. 27 (3), pp. 337-43. Date of Electronic Publication: 2011 Nov 30.Publisher: Oxford University Press Country of Publication: England NLM ID: 8707812 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner.

Authors : Roy S; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Denver, Aurora, CO 80045, USA.; Deep G

Subjects: Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism ; Silymarin/Silymarin/Silymarin/*pharmacology

Source: Carcinogenesis [Carcinogenesis] 2012 Mar; Vol. 33 (3), pp. 629-36. Date of Electronic Publication: 2011 Dec 12.Publisher: Irl Press At Oxford University Press Country of Publication: England NLM ID: 8008055 Publication Model: Print-Electronic Cited Medium:

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نتائج البحث

فلترة النتائج

Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats.

Exceptional origin activation revealed by comparative analysis in two laboratory yeast strains.

Exo1 phosphorylation inhibits exonuclease activity and prevents fork collapse in rad53 mutants independently of the 14-3-3 proteins.

Therapeutic Co-targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer.

Ddc2ATRIP promotes Mec1ATR activation at RPA-ssDNA tracts.

DNA replication checkpoint signaling depends on a Rad53-Dbf4 N-terminal interaction in Saccharomyces cerevisiae.

A prolyl-hydroxylase inhibitor, ethyl-3,4-dihydroxybenzoate, induces cell autophagy and apoptosis in esophageal squamous cell carcinoma cells via up-regulation of BNIP3 and N-myc downstream-regulated gene-1.

A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1.

Impact of heterozygous c.657-661del, p.I171V and p.R215W mutations in NBN on nibrin functions.

Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner.

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