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Subject : cell cycle proteins
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Academic Journal

DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach.

  • Authors : Wu KZ; Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Ireland.; Wang GN

Subjects: Antigens, Neoplasm/Antigens, Neoplasm/Antigens, Neoplasm/*metabolism ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Centromere/Centromere/Centromere/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2016 Oct 14; Vol. 44 (18), pp. 8786-8798. Date of Electronic Publication: 2016 Jul 12.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Elucidating the DDK-dependent step in replication initiation.

  • Authors : Araki H; National Institute of Genetics, Mishima, Japan.

Subjects: DNA Replication*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics; Humans

  • Source: The EMBO journal [EMBO J] 2016 May 02; Vol. 35 (9), pp. 907-8. Date of Electronic Publication: 2016 Mar 22.Publisher: Wiley Blackwell Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase.

  • Authors : Herrera MC; DNA Replication Group, Institute of Clinical Sciences, Imperial College London, London W12 0NN, UK.; Tognetti S

Subjects: Replication Origin*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Minichromosome Maintenance Proteins/Minichromosome Maintenance Proteins/Minichromosome Maintenance Proteins/*metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2015 Dec 02; Vol. 43 (21), pp. 10238-50. Date of Electronic Publication: 2015 Sep 03.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffolds.

  • Authors : Sasi NK; Laboratory of Genome Integrity and Tumorigenesis, Van Andel Research Institute (VARI), Grand Rapids, MI, United States of America; Graduate Program in Genetics, Michigan State University, East Lansing, MI, United States of America.

Subjects: Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*antagonists & inhibitors ; Cell Line, Tumor/Cell Line, Tumor/Cell Line, Tumor/*drug effects ; Piperidones/Piperidones/Piperidones/*pharmacology

  • Source: PloS one [PLoS One] 2014 Nov 20; Vol. 9 (11), pp. e113300. Date of Electronic Publication: 2014 Nov 20 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Dbf4-Dependent Kinase (DDK)-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A in

Subjects: Saccharomyces cerevisiae Proteins; Chromosomal Proteins, Non-Histone; Centromere

  • Source: G3: Genes|Genomes|Genetics

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Overlapping Roles in Chromosome Segregation for Heterochromatin Protein 1 (Swi6) and DDK in

Subjects: DNA Replication; Chromosomal Proteins, Non-Histone; Centromere

  • Source: Genetics

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Academic Journal

Firing of Replication Origins Frees Dbf4-Cdc7 to Target Eco1 for Destruction

Subjects: Biochemistry and Cell Biology; Biological Sciences; Acetyltransferases

  • Source: Current Biology. 27(18)

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Academic Journal

Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation.

  • Authors : Deegan TD; The Francis Crick Institute, Clare Hall Laboratory, South Mimms Herts, UK.; Yeeles JT

Subjects: Replication Origin*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism

  • Source: The EMBO journal [EMBO J] 2016 May 02; Vol. 35 (9), pp. 961-73. Date of Electronic Publication: 2016 Feb 24.Publisher: Wiley Blackwell Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel role of DONSON in CMG helicase assembly during vertebrate DNA replication initiation.

Subjects: *DNA replication; *DNA helicases; *REPLISOMES

  • Source: EMBO Journal. 9/4/2023, Vol. 42 Issue 17, p1-17. 17p.

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Academic Journal

DNA replication checkpoint signaling depends on a Rad53-Dbf4 N-terminal interaction in Saccharomyces cerevisiae.

  • Authors : Chen YC; Laboratory of Genome Integrity and Tumorigenesis, Van Andel Research Institute, Grand Rapids, MI 49503, USA.; Kenworthy J

Subjects: DNA Replication* ; S Phase Cell Cycle Checkpoints* ; Signal Transduction*

  • Source: Genetics [Genetics] 2013 Jun; Vol. 194 (2), pp. 389-401. Date of Electronic Publication: 2013 Apr 05.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print-Electronic Cited Medium: Internet

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