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  • 1-10 ل  792 نتائج ل ""CHECKPOINT kinase 1""

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Subject : cell cycle proteins
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Academic Journal

Interaction of DDB1 with NBS1 in a DNA Damage Checkpoint Pathway.

  • Authors : Lim HE; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, Republic of Korea.; Research Institute for Future Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea.

Subjects: Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/genetics ; DNA Damage*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 05; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers.

  • Authors : Moens S; VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.; Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), 3000, Leuven, Belgium.

Subjects: Carboplatin/Carboplatin/Carboplatin/*pharmacology ; Cell Cycle Checkpoints/Cell Cycle Checkpoints/Cell Cycle Checkpoints/*drug effects ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics

  • Source: Scientific reports [Sci Rep] 2021 Feb 04; Vol. 11 (1), pp. 3176. Date of Electronic Publication: 2021 Feb 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mitotic entry upon Topo II catalytic inhibition is controlled by Chk1 and Plk1.

  • Authors : Arroyo M; Departamento de Biología Experimental, Universidad de Jaén, Spain.; Cañuelo A

Subjects: Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Checkpoint Kinase 1/Checkpoint Kinase 1/Checkpoint Kinase 1/*metabolism ; DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/*metabolism

  • Source: The FEBS journal [FEBS J] 2020 Nov; Vol. 287 (22), pp. 4933-4951. Date of Electronic Publication: 2020 Mar 20.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe.

  • Authors : Patel JA; Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794, USA.; Zezelic C

Subjects: Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/metabolism ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism ; DNA Replication*

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Jul 07; Vol. 51 (12), pp. 6246-6263.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

  • Authors : Guo Y; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Division of Molecular Carcinogenesis, Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

Subjects: DNA Replication* ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/*genetics

  • Source: Genome medicine [Genome Med] 2021 Oct 18; Vol. 13 (1), pp. 166. Date of Electronic Publication: 2021 Oct 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1.

  • Authors : Abreu CM; Centre for Chromosome Biology, School of Natural Science, National University of Ireland Galway, Galway, Ireland.; Kumar R

Subjects: DNA Damage*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Protein Kinases/Protein Kinases/Protein Kinases/*metabolism

  • Source: PLoS genetics [PLoS Genet] 2013 Apr; Vol. 9 (4), pp. e1003310. Date of Electronic Publication: 2013 Apr 04.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

PARP1 and CHK1 coordinate PLK1 enzymatic activity during the DNA damage response to promote homologous recombination-mediated repair.

  • Authors : Peng B; Guangdong Key Laboratory for Genome Stability & Disease Prevention and Carson International Cancer Center, Marshall Laboratory of Biomedical Engineering, Shenzhen University School of Medicine, Shenzhen, Guangdong 518060, China.; Shi R

Subjects: Recombinational DNA Repair*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Checkpoint Kinase 1/Checkpoint Kinase 1/Checkpoint Kinase 1/*metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2021 Jul 21; Vol. 49 (13), pp. 7554-7570.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Cep55 overexpression promotes genomic instability and tumorigenesis in mice.

  • Authors : Sinha D; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, 4006, QLD, Australia.; School of Environment and Sciences, Griffith University, Nathan, 4111, QLD, Australia.

Subjects: Gene Expression* ; Genomic Instability*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics

  • Source: Communications biology [Commun Biol] 2020 Oct 21; Vol. 3 (1), pp. 593. Date of Electronic Publication: 2020 Oct 21.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Non-SMC condensin I complex subunit H mediates mature chromosome condensation and DNA damage in pancreatic cancer cells.

  • Authors : Kim JH; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, 13620, Republic of Korea. .; Youn Y

Subjects: Chromosome Aberrations* ; DNA Damage*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism

  • Source: Scientific reports [Sci Rep] 2019 Nov 29; Vol. 9 (1), pp. 17889. Date of Electronic Publication: 2019 Nov 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

ERK-mediated TIMELESS expression suppresses G2/M arrest in colon cancer cells.

  • Authors : Neilsen BK; Eppley Institute, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.; Frodyma DE

Subjects: Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*metabolism ; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*pathology

  • Source: PloS one [PLoS One] 2019 Jan 10; Vol. 14 (1), pp. e0209224. Date of Electronic Publication: 2019 Jan 10 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 ل  792 نتائج ل ""CHECKPOINT kinase 1""