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The rise and fall of the CD28 superagonist TGN1412 and its return as TAB08: a personal account.

• Authors : Hünig, Thomas¹

Subjects: *CD28 antigen; *MONOCLONAL antibodies; *T cells

• Source: FEBS Journal. Sep2016, Vol. 283 Issue 18, p3325-3334. 10p.

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After TGN1412: Recent developments in cytokine release assays.

• Authors : Stebbings, R.¹ (AUTHOR) ; Eastwood, D.¹ (AUTHOR); Poole, S.¹ (AUTHOR)

• Source: Journal of Immunotoxicology. Jan-Mar2013, Vol. 10 Issue 1, p75-82. 8p. 1 Color Photograph, 4 Graphs.

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TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model.

• Authors : Weißmüller, Sabrina¹; Kronhart, Stefanie¹; Kreuz, Dorothea²

Subjects: *LYMPHOPENIA; *CYTOKINES; *LABORATORY mice

• Source: PLoS ONE. 3/9/2016, Vol. 11 Issue 3, p1-19. 19p.

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Response to 'Storm forecasting: additional lessons from the CD28 superagonist TGN1412 trial'.

• Authors : Hünig, Thomas¹

• Source: Nature Reviews Immunology. Oct2012, Vol. 12 Issue 10, p740-740. 1p.

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