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Cas9-catalyzed DNA Cleavage Generates Staggered Ends: Evidence from Molecular Dynamics Simulations

• Authors : Zuo, Zhicheng; Liu, Jin

Subjects: Bacterial Proteins / chemistry; Bacterial Proteins / genetics; CRISPR-Associated Protein 9

• Source: Scientific Reports

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The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis

• Authors : Rosado, Leonardo Astolfi; Wahni, Khadija; Degiacomi, Giulia ...

Subjects: Models, Molecular; Prodrugs/chemistry; Protein Conformation

• Source: Journal of Biological Chemistry. 292:13097-13110

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Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors

• Authors : Hugo Pacheco de Freitas Fraga; Cécile Morlot; Diego F. Gauto ...

Subjects: DYNAMICS; PROTEINS; [SDV]Life Sciences [q-bio]

• Source: Sci AdvDigital.CSIC. Repositorio Institucional del CSICConsejo Superior de Investigaciones Científicas (CSIC)instnameZaguán. Repositorio Digital de la Universidad de

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Another look at the mechanism involving trimeric dUTPases inStaphylococcus aureuspathogenicity island induction involves novel players in the party

• Authors : Alberto Marina; Janine Bowring; Suzanne Humphrey ...

Subjects: Estafilococos; Medical bacteriology; Protein Conformation

• Source: Nucleic Acids ResDigital.CSIC. Repositorio Institucional del CSICinstnameConsejo Superior de Investigaciones Científicas (CSIC)CEU Repositorio InstitucionalFundación

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Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors

• Authors : Felix, J; Weinhäupl, K; Chipot, C ...

Subjects: Allosteric Regulation; Bacterial Proteins / antagonists & inhibitors; Bacterial Proteins / chemistry

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The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes

• Authors : Rengachari, S.; Bezerra, G. A.; Oberer, M.

Subjects: 0301 basic medicine; Phenylmethylsulfonyl Fluoride: chemistry; Molecular Sequence Data

• Source: Biochim Biophys ActaBiochimica et biophysica acta / Biomembranes 1821, 1012-1021 (2012). doi:10.1016/j.bbalip.2012.04.006

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Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens

• Authors : Smith, Roxanne P; Mohanty, Biswaranjan; Mowlaboccus, Shakeel

Subjects: Amino Acid Sequence; Bacterial Proteins - chemistry; Bacterial Proteins - metabolism

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Reversal of the Substrate Specificity of CMP N-Glycosidase to dCMP

• Authors : Sikowitz, Megan D.; Cooper, Lisa E.; Begley, Tadhg P. ...

Subjects: Models, Molecular; MESH: Pentosyltransferases/genetics; MESH: Pentosyltransferases/chemistry

• Source: BiochemistryBiochemistry, 2013, 52 (23), pp.4037-4047. ⟨10.1021/bi400316p⟩Biochemistry, American Chemical Society, 2013, 52 (23), pp.4037-4047. ⟨10.1021/bi400316p⟩

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Structural basis for substrate recognition by Erwinia chrysanthemi GH30 glucuronoxylanase

• Authors : Urbanikova, L.; Vrshanska, M.; Krogh, K. B. R. M.

Subjects: Xylosidases: metabolism; Models, Molecular; Xylosidases: genetics

• Source: FEBS letters 278, 2105-2116 (2011). doi:10.1111/j.1742-4658.2011.08127.x

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Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE

• Authors : Wulf Blankenfeldt; Linda S. Thomashow; Manfred Roessle

Subjects: Burkholderia: enzymology; 0301 basic medicine; Burkholderia

• Source: The journal of biological chemistry 286, 18213-18221 (2011). doi:10.1074/jbc.M110.183418

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