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Subject : business Subject : chemistry.chemical_compound Subject : clinical trial Subject : pharmaceutical science فلترة بواسطة : مؤلف

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Bioequivalence of Esaxerenone Conventional Tablet and Orally Disintegrating Tablet: Two Single‐Dose Crossover Studies in Healthy Japanese Men

Authors : Akifumi, Kurata; Takashi, Eto; Junko, Tsutsumi

Subjects: Male; Cross-Over Studies; Japan

Source: Clinical Pharmacology in Drug Development. 11:957-965

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Model‐based assessments of CYP3A‐mediated drug‐drug interaction risk of milademetan

Authors : Ying Hong; Frank LaCreta; Hitoshi Ishizuka

Subjects: Posaconazole; Physiologically based pharmacokinetic modelling; Indoles

Source: Clinical and Translational ScienceClinical and Translational Science, Vol 14, Iss 6, Pp 2220-2230 (2021)

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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Mirogabalin When Coadministered With Lorazepam, Zolpidem, Tramadol, or Ethanol: Results From Drug-Drug Interaction Studies in Healthy Subjects

Authors : Jeanne Mendell; Alexander Currie; James Dow

Subjects: Adult; Male; Zolpidem

Source: Clinical Pharmacology in Drug Development. 7:597-612

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A Randomized, Placebo-Controlled, Double-Blind Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Repeated Doses of Mirogabalin in Healthy Asian Volunteers

Authors : Victor Dishy; Hitoshi Ishizuka; Lisa Johnson

Subjects: Adult; Male; Drug-Related Side Effects and Adverse Reactions

Source: Clinical Pharmacology in Drug Development. 7:661-669

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Circulating miRNA Signature as a Potential Biomarker for the Prediction of Analgesic Efficacy of Hydromorphone

Authors : Kaoru Toyama; Kenji Watanabe; Hitoshi Ishizuka

Subjects: Male; cancer pain; Analgesic

Source: International Journal of Molecular Sciences, Vol 20, Iss 7, p 1665 (2019)International Journal of Molecular SciencesVolume 20Issue 7

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Identification of Circulating miRNAs Differentially Regulated by Opioid Treatment

Authors : Kaoru Toyama; Hitoshi Ishizuka; Kenji Watanabe

Subjects: 0301 basic medicine; Adult; Male

Source: International Journal of Molecular Sciences; Volume 18; Issue 9; Pages: 1991International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 18, Iss 9, p 1991

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Pharmacokinetic Bioequivalence Studies of an Extended-Release Oxycodone Hydrochloride Tablet in Healthy Japanese Subjects Under Fasting and Fed Conditions Without an Opioid Antagonist

Authors : Hidetoshi Furuie; Hitoshi Ishizuka; Kaoru Toyama

Subjects: Adult; Male; medicine.drug_class

Source: Drugs in R&D

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