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Application of unbound liver-to-plasma concentration ratio to quantitative projection of cytochrome P450-mediated drug-drug interactions using physiologically based pharmacokinetic modelling approach.

• Authors : Iwasaki S; a Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Co., Ltd. , Fujisawa , Kanagawa , Japan.; b Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co. , Cambridge , MA , USA.

Subjects: Drug Interactions* ; Pharmacokinetics*; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism

• Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2019 Nov; Vol. 49 (11), pp. 1251-1259. Date of Electronic Publication: 2019 Feb 03.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Personalise vitamin D3 using physiologically based pharmacokinetic modelling

• Authors : Tao You; Zhonghui Huang

Subjects: Vitamin; Physiologically based pharmacokinetic modelling; Time Factors

• Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 7, Pp 723-734 (2021)CPT: Pharmacometrics & Systems Pharmacology

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Physiologically‐Based Pharmacokinetic Modelling of Creatinine‐Drug Interactions in the Chronic Kidney Disease Population

• Authors : Daniel Scotcher; Rajkumar Chinnadurai; Hiroyuki Takita

Subjects: Adult; Male; Physiologically based pharmacokinetic modelling

• Source: Takita, H, Scotcher, D, Chinnadurai, R, Kalra, P & Galetin, A 2020, ' Physiologically-based Pharmacokinetic

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Modelled plasma concentrations of pemafibrate with co-administered typical cytochrome P450 inhibitors clopidogrel, fluconazole or clarithromycin predicted by physiologically based pharmacokinetic modelling in virtual populations

• Authors : Makiko Shimizu; Hiroshi Yamazaki; Shin-ichiro Ogawa

Subjects: Physiologically based pharmacokinetic modelling; Cirrhosis; Itraconazole

• Source: Xenobiotica. 50:1413-1422

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Simulation of the In Vivo Fate of Polymeric Nanoparticles Traced by Environment-Responsive Near-Infrared Dye: A Physiologically Based Pharmacokinetic Modelling Approach

• Authors : Xiaoqiang Xiang; Haisheng He; Ning Ding

Subjects: Biodistribution; Physiologically based pharmacokinetic modelling; Polymers

• Source: MoleculesMolecules, Vol 26, Iss 1271, p 1271 (2021)Molecules; Volume 26; Issue 5; Pages: 1271

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Application of unbound liver-to-plasma concentration ratio to quantitative projection of cytochrome P450-mediated drug–drug interactions using physiologically based pharmacokinetic modelling approach

• Authors : Shinji Iwasaki; Atsutoshi Furuta; Mai Kosaka

Subjects: Male; Drug; Physiologically based pharmacokinetic modelling

• Source: Xenobiotica. 49:1251-1259

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Estimation of residue depletion of cyadox and its marker residue in edible tissues of pigs using physiologically based pharmacokinetic modelling

• Authors : Jim E. Riviere; Lingli Huang; Xuan Zhou

Subjects: Drug; Physiologically based pharmacokinetic modelling; Animal feed

• Source: Food additivescontaminants. Part A, Chemistry, analysis, control, exposurerisk assessment. 32(12)

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Physiologically Based Pharmacokinetic Modelling of Cabozantinib to Simulate Enterohepatic Recirculation, Drug–Drug Interaction with Rifampin and Liver Impairment.

• Authors : Gerner, Bettina¹ (AUTHOR) ; Scherf-Clavel, Oliver¹ (AUTHOR)

• Source: Pharmaceutics. Jun2021, Vol. 13 Issue 6, p778. 1p.

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Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

• Authors : Malcolm Rowland; Trudy Rodgers

Subjects: Octanols; Quantitative structure–activity relationship; Physiologically based pharmacokinetic modelling

• Source: Journal of Pharmaceutical Sciences. 95:1238-1257

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Pharmacokinetic predictions in children by using the physiologically based pharmacokinetic modelling

• Authors : F. Bouzom; B. Walther

Subjects: Adult; medicine.medical_specialty; Pediatrics

• Source: Fundamentalclinical pharmacology. 22(6)

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