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Subject : biochemistry

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Metabolism of gartanin in liver microsomes and its modulating effects on cytochrome P450s

Authors : Tao, Jia; Ai, Hao

Subjects: Pharmacology; Xanthones; Health, Toxicology and Mutagenesis

Source: Xenobiotica. 52:335-345

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Spectroscopic observations of β-eudesmol binding to human cytochrome P450 isoforms 3A4 and 1A2, but not to isoforms 2C9, 2C19, and 2D6

Authors : Dawid, Krenc; Kesara, Na-Bangchang

Subjects: Pharmacology; Spectrum Analysis; Health, Toxicology and Mutagenesis

Source: Xenobiotica. 52:199-208

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Metabolic activation of zolmitriptan mediated by CYP2D6

Authors : Ying Peng; Chen Sun; Jiang Zheng

Subjects: Quinidine; Health, Toxicology and Mutagenesis; Pharmacology

Source: Xenobiotica. 51:1292-1302

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Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine

Authors : Juri Arima; Yurina Michihiro; Toshiro Niwa

Subjects: Fluphenazine; Arginine; Dopamine

Source: Xenobiotica. 51:1229-1235

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Effect of naringenin on the pharmacokinetics of metoprolol succinate in rats

Authors : Surya Sandeep Mullapudi; Yamini Gullapalli; Sridhar Vemulapalli

Subjects: Male; Naringenin; Health, Toxicology and Mutagenesis

Source: Xenobiotica. 51:926-932

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Succinic acid inhibits the activity of cytochrome P450 (CYP450) enzymes

Authors : Bin Sun; Bingyan Xia; Yuzhu Li

Subjects: CYP2C9; CYP2D6; CYP3A4

Source: Pharmaceutical Biologyarticle-version (VoR) Version of RecordPharmaceutical Biology, Vol 58, Iss 1, Pp 1159-1164 (2020)

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Pirfenidone 5-hydroxylation is mainly catalysed by CYP1A2 and partly catalysed by CYP2C19 and CYP2D6 in the human liver

Authors : Yongjie Zhang; Rei Sato; Masataka Nakano

Subjects: CYP2D6; CYP2B6; Pyridones

Source: Xenobiotica; the fate of foreign compounds in biological systems. 51(12)

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Regioselective hydroxylation of an antiarrhythmic drug, propafenone, mediated by rat liver cytochrome P450 2D2 differs from that catalyzed by human P450 2D6

Authors : Norie Murayama; Shotaro Uehara; Hiroshi Yamazaki

Subjects: Adult; Male; Drug

Source: Xenobiotica. 49:1323-1331

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In vitro inhibitory effects of dihydromyricetin on human liver cytochrome P450 enzymes

Authors : Xiaohua Li; Lu Liu; Sen Sun

Subjects: CYP2D6; Flavonols; ved/biology.organism_classification_rank.species

Source: Pharmaceutical Biology, Vol 55, Iss 1, Pp 1868-1874 (2017)Pharmaceutical Biology

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Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences

Authors : Jeffrey P. Jones; Thomas H. Rushmore; Dmitri R. Davydov

Subjects: 0301 basic medicine; Allosteric regulation; Reductase

Source: Biochemical Journal. 474:3523-3542

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فلترة النتائج

Metabolism of gartanin in liver microsomes and its modulating effects on cytochrome P450s

Spectroscopic observations of β-eudesmol binding to human cytochrome P450 isoforms 3A4 and 1A2, but not to isoforms 2C9, 2C19, and 2D6

Metabolic activation of zolmitriptan mediated by CYP2D6

Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine

Effect of naringenin on the pharmacokinetics of metoprolol succinate in rats

Succinic acid inhibits the activity of cytochrome P450 (CYP450) enzymes

Pirfenidone 5-hydroxylation is mainly catalysed by CYP1A2 and partly catalysed by CYP2C19 and CYP2D6 in the human liver

Regioselective hydroxylation of an antiarrhythmic drug, propafenone, mediated by rat liver cytochrome P450 2D2 differs from that catalyzed by human P450 2D6

In vitro inhibitory effects of dihydromyricetin on human liver cytochrome P450 enzymes

Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences

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