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Virtual screening of natural compounds as selective inhibitors of polo-like kinase-1 at C-terminal polo box and N-terminal catalytic domain

• Authors : Olusola Olalekan Elekofehinti; Femi Olawale; Opeyemi Iwaloye

Subjects: Pharmacology; 0303 health sciences; Chemical Sciences not elsewhere classified

• Source: Journal of Biomolecular Structure and Dynamics. 40:13606-13624

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Additional file 1 of Undetectable off-target effects induced by FokI catalytic domain in mouse embryos

• Authors : Long Xie; Hu Feng; Zhifang Li

Subjects: Biochemistry; Genetics; Developmental Biology

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Surface plasmon resonance using the catalytic domain of soluble guanylate cyclase allows the detection of enzyme activators

• Authors : Mota, F; Allerston, CK; Hampden-Smith, K

Subjects: 0301 basic medicine; Clinical Biochemistry; Guanosine Monophosphate

• Source: Bioorg Med Chem Lett

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Lactobacillus plantarum WCFS1 β-Fructosidase: Evidence for an Open Funnel-Like Channel Through the Catalytic Domain with Importance for the Substrate Selectivity

• Authors : Mendoza Llerenas, Edgar Omar; Pérez, David Javier; Gómez Sandoval, Zeferino ...

Subjects: 0301 basic medicine; Sucrose; computer simulations

• Source: Applied Biochemistry and Biotechnology. 180:1056-1075

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Evolutionary Analysis Reveals the Role of a Non-Catalytic Domain of Peptidyl Arginine Deiminase 2 in Transcriptional Regulation

• Authors : José Luis Villanueva-Cañas; Narcis Fernandez-Fuentes; Dominik Saul ...

Subjects: 0301 basic medicine; Biological sciences; 03 medical and health sciences

• Source: iScienceiScience, Vol 27, Iss 4, Pp 109584-(2024)iScience, 2024, 27 (4), pp.109584. ⟨10.1016/j.isci.2024.109584⟩

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Alendronate promotes plasmin‐mediated MMP‐9 inactivation by exposing cryptic plasmin degradation sites within the MMP‐9 catalytic domain

• Authors : FARINA, ANTONIETTA; CAPPABIANCA, LUCIA ANNAMARIA; Di Ianni N

Subjects: hemopexin-domain; bisphosphonate alendronate; irreversible inhibition

• Source: FEBS Letters. 586:2366-2374

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Specificity of Dnmt1 for Methylation of Hemimethylated CpG Sites Resides in Its Catalytic Domain

• Authors : Anita Smarandache; Sergey Ragozin; Renata Z. Jurkowska

Subjects: Pharmacology; 0303 health sciences; Clinical Biochemistry

• Source: Chemistry & Biology. 19:572-578

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Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1

• Authors : P. Hinchliffe; Qiu Yang; Edward Portal

Subjects: Models, Molecular; Amoebiasis: Pathogenesis and Clinical Management; Protein Conformation

• Source: Sci RepHinchliffe, P, Yang, Q, Portal, E, Young, T, Li, H, Tooke, C, Mendes de Carvalho, M, Paterson, N, Brem, J, Ritivirool, P, Tansawai, U, Lei, L, Li, M, Shen, Z, Wang, Y, Schofield, C,

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Virtual screening of natural compounds as selective inhibitors of polo-like kinase-1 at C-terminal polo box and N-terminal catalytic domain

• Authors : Femi Olawale (11587388); Opeyemi Iwaloye (10801772); Olusola Olalekan Elekofehinti (9459988)

Subjects: Biochemistry; Pharmacology; Biological Sciences not elsewhere classified

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Influence of lysophospholipid hydrolysis by the catalytic domain of neuropathy target esterase on the fluidity of bilayer lipid membranes

• Authors : Robert Y. Ofoli; Aaron J. Greiner; R. Mark Worden

Subjects: Bilayer membrane fluidity; Supported bilayer lipid membrane; Light

• Source: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1798:1533-1539

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