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Academic Journal

Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation.

  • Authors : Stępnicki P; Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.; Wronikowska-Denysiuk O

Subjects: Schizophrenia*/Schizophrenia*/Schizophrenia*/drug therapy ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/pharmacology ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/chemistry

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2209828.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Serotonin transporter functional polymorphisms potentially increase risk of schizophrenia separately and as a haplotype.

  • Authors : Ghamari R; Department of Genetics, Faculty of Biology, Kharazmi University, Tehran, Iran.; Yazarlou F

Subjects: Monoamine Oxidase/Monoamine Oxidase/Monoamine Oxidase/*genetics ; Schizophrenia/Schizophrenia/Schizophrenia/*genetics ; Serotonin Plasma Membrane Transport Proteins/Serotonin Plasma Membrane Transport Proteins/Serotonin Plasma Membrane Transport Proteins/*genetics

  • Source: Scientific reports [Sci Rep] 2022 Jan 25; Vol. 12 (1), pp. 1336. Date of Electronic Publication: 2022 Jan 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Population pharmacokinetic analysis of ulotaront in subjects with schizophrenia.

Subjects: Pyrans*/Pyrans*/Pyrans*/pharmacokinetics ; Pyrans*/Pyrans*/Pyrans*/therapeutic use ; Receptors, G-Protein-Coupled*/Receptors, G-Protein-Coupled*/Receptors, G-Protein-Coupled*/agonists

  • Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2021 Oct; Vol. 10 (10), pp. 1245-1254. Date of Electronic Publication: 2021 Aug 10.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Serotonergic-Muscarinic Interaction within the Prefrontal Cortex as a Novel Target to Reverse Schizophrenia-Related Cognitive Symptoms.

  • Authors : Cieślik P; Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.; Radulska A

Subjects: Cholinergic Agents/Cholinergic Agents/Cholinergic Agents/*pharmacology ; Cognitive Dysfunction/Cognitive Dysfunction/Cognitive Dysfunction/*drug therapy ; Prefrontal Cortex/Prefrontal Cortex/Prefrontal Cortex/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 10; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Dopamine (DRD2) and Serotonin (HTR2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia.

  • Authors : Alladi CG; Department of Pharmacology, Jawaharlal Institute of Post-graduate Medical Education and Research, Puducherry, 605006, India.; Inserm, U1144, Paris, F-75006, France.

Subjects: Antipsychotic Agents/Antipsychotic Agents/Antipsychotic Agents/*therapeutic use ; Risperidone/Risperidone/Risperidone/*therapeutic use ; Schizophrenia/Schizophrenia/Schizophrenia/*drug therapy

  • Source: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2019 Jun; Vol. 33 (3), pp. 355-364. Date of Electronic Publication: 2018 Nov 21.Publisher: Blackwell Science Country of Publication: England NLM ID: 8710411 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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