نتائج البحث

Safety and efficacy of MIKE-1 in patients with advanced pancreatic cancer: a study protocol for an open-label phase I/II investigator-initiated clinical trial based on a drug repositioning approach that reprograms the tumour stroma.

• Authors : Mizutani Y; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Pathology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Subjects: Albumins/Albumins/Albumins/*administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*administration & dosage ; Benzoates/Benzoates/Benzoates/*administration & dosage

• Source: BMC cancer [BMC Cancer] 2022 Feb 24; Vol. 22 (1), pp. 205. Date of Electronic Publication: 2022 Feb 24.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Inhibition of epithelial-mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist.

• Authors : Kobayashi Y; Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube City, Yamaguchi, 755-8505, Japan.; Tokuda K

Subjects: Benzoates/Benzoates/Benzoates/*pharmacology ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*drug effects ; Retinal Pigment Epithelium/Retinal Pigment Epithelium/Retinal Pigment Epithelium/*metabolism

• Source: Scientific reports [Sci Rep] 2021 Jun 04; Vol. 11 (1), pp. 11842. Date of Electronic Publication: 2021 Jun 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Tamibarotene inhibit the accumulation of fibrocyte and alleviate renal fibrosis by IL-17A.

• Authors : Li L; Department of Nephrology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Luo R

Subjects: Benzoates/Benzoates/Benzoates/*pharmacology ; Fibrosis/Fibrosis/Fibrosis/*drug therapy ; Fibrosis/Fibrosis/Fibrosis/*metabolism

• Source: Renal failure [Ren Fail] 2020 Nov; Vol. 42 (1), pp. 1173-1183.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print Cited Medium: Internet ISSN: 1525-6049

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A synthetic retinoic acid receptor agonist Am80 ameliorates renal fibrosis via inducing the production of alpha-1-acid glycoprotein.

• Authors : Watanabe H; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto, 862-0973, Japan. .; Bi J

Subjects: Benzoates/Benzoates/Benzoates/*pharmacology ; Kidney/Kidney/Kidney/*drug effects ; Orosomucoid/Orosomucoid/Orosomucoid/*metabolism

• Source: Scientific reports [Sci Rep] 2020 Jul 10; Vol. 10 (1), pp. 11424. Date of Electronic Publication: 2020 Jul 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Novel PEG-grafted nanostructured lipid carrier for systematic delivery of a poorly soluble anti-leukemia agent Tamibarotene: characterization and evaluation.

• Authors : Liu X; The School of Pharmaceutical Science, Shandong University , Ji'nan, Shandong Province , PR China.; Zhang Z

Subjects: Drug Delivery Systems*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage ; Benzoates/Benzoates/Benzoates/*administration & dosage

• Source: Drug delivery [Drug Deliv] 2015 Feb; Vol. 22 (2), pp. 223-9. Date of Electronic Publication: 2014 Feb 21.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9417471 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Effect of Specific Retinoic Acid Receptor Agonists on Noise-Induced Hearing Loss.

• Authors : Kwak SH; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Korea. .; Nam GS

Subjects: Benzoates/Benzoates/Benzoates/*therapeutic use ; Hearing Loss, Noise-Induced/Hearing Loss, Noise-Induced/Hearing Loss, Noise-Induced/*prevention & control ; Naphthols/Naphthols/Naphthols/*therapeutic use

• Source: International journal of environmental research and public health [Int J Environ Res Public Health] 2019 Sep 16; Vol. 16 (18). Date of Electronic Publication: 2019 Sep 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238455 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-4601

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Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580.

• Authors : Lu Y; Division of Hematology-Oncology, Department of Medicine, Tisch Cancer Center, Mount Sinai School of Medicine, New York, NY, USA.; Bertran S

Subjects: Benzoates/Benzoates/Benzoates/*pharmacology ; Mammary Neoplasms, Experimental/Mammary Neoplasms, Experimental/Mammary Neoplasms, Experimental/*pathology ; Mammary Tumor Virus, Mouse/Mammary Tumor Virus, Mouse/Mammary Tumor Virus, Mouse/*genetics

• Source: Oncogene [Oncogene] 2010 Jun 24; Vol. 29 (25), pp. 3665-76. Date of Electronic Publication: 2010 May 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease.

• Authors : Melis M; Department of Pharmacology, Weill Cornell Medicine, New York, NY, United States of America.; Tang XH

Subjects: Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/chemically induced ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/drug therapy ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/metabolism

• Source: PloS one [PLoS One] 2019 Jan 24; Vol. 14 (1), pp. e0211071. Date of Electronic Publication: 2019 Jan 24 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Tamibarotene: AM 80, retinobenzoic acid, Tamibaro.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Benzoates/Benzoates/Benzoates/*pharmacology ; Leukemia, Promyelocytic, Acute/Leukemia, Promyelocytic, Acute/Leukemia, Promyelocytic, Acute/*drug therapy

• Source: Drugs in R&D [Drugs R D] 2004; Vol. 5 (6), pp. 359-62.Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 100883647 Publication Model: Print Cited Medium: Print ISSN:

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Antimyeloma effects of a novel synthetic retinoid Am80 (Tamibarotene) through inhibition of angiogenesis.

• Authors : Sanda T; Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.; Kuwano T

Subjects: Benzoates/Benzoates/Benzoates/*pharmacology ; Cornea/Cornea/Cornea/*blood supply ; Multiple Myeloma/Multiple Myeloma/Multiple Myeloma/*drug therapy

• Source: Leukemia [Leukemia] 2005 Jun; Vol. 19 (6), pp. 901-9.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print Cited Medium: Print

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