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Academic Journal

Charged Amino Acids in the Transmembrane Helix Strongly Affect the Enzyme Activity of Aromatase.

Authors : Günther J; Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.; Schuler G

Subjects: Aromatase*/Aromatase*/Aromatase*/genetics ; Aromatase*/Aromatase*/Aromatase*/metabolism; Animals

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A Dehydrogenase Dual Hydrogen Abstraction Mechanism Promotes Estrogen Biosynthesis: Can We Expand the Functional Annotation of the Aromatase Enzyme?

Authors : Spinello A; CNR-IOM-Democritos, c/o International School for Advanced Studies (SISSA), via Bonomea 265, 34136, Trieste, Italy.; Pavlin M

Subjects: Androstenedione/Androstenedione/Androstenedione/*metabolism ; Aromatase/Aromatase/Aromatase/*metabolism ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*chemistry

Source: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2018 Jul 25; Vol. 24 (42), pp. 10840-10849. Date of Electronic Publication: 2018 Jun 25.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765

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Academic Journal

Modulation of expression of 17-Hydroxylase/17,20 lyase (CYP17) and P450 aromatase (CYP19) by inhibition of MEK1 in a human ovarian granulosa-like tumor cell line.

Authors : Huang X; a State Key Laboratory of Chemistry for Life Science & Jiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University , Nanjing , China and.; Jin J

Subjects: Aromatase/Aromatase/Aromatase/*metabolism ; Flavonoids/Flavonoids/Flavonoids/*therapeutic use ; Granulosa Cell Tumor/Granulosa Cell Tumor/Granulosa Cell Tumor/*drug therapy Granulosa cell tumor of the ovary

Source: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2016; Vol. 32 (3), pp. 201-5. Date of Electronic Publisher: Informa Healthcare Country of Publication: England NLM ID: 8807913 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia.

Authors : Perez-Sepulveda A; Department of Obstetrics and Gynecology, Laboratory of Reproductive Biology, Faculty of Medicine, Universidad de Los Andes, Santiago, Chile.; Monteiro LJ

Subjects: Aromatase/Aromatase/Aromatase/*deficiency ; Aromatase/Aromatase/Aromatase/*metabolism ; Ischemia/Ischemia/Ischemia/*metabolism

Source: PloS one [PLoS One] 2015 Oct 07; Vol. 10 (10), pp. e0139682. Date of Electronic Publication: 2015 Oct 07 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Aromatase overexpression induces malignant changes in estrogen receptor α negative MCF-10A cells.

Authors : Wang J; Department of Medicine, University of Virginia Health System, Charlottesville, VA, USA.; Gildea JJ

Subjects: Aromatase/Aromatase/Aromatase/*metabolism ; Estrogen Receptor alpha/Estrogen Receptor alpha/Estrogen Receptor alpha/*metabolism; Androstenedione/Androstenedione/Androstenedione/metabolism

Source: Oncogene [Oncogene] 2013 Oct 31; Vol. 32 (44), pp. 5233-40. Date of Electronic Publication: 2012 Nov 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Bisphenol A disrupts steroidogenesis in human H295R cells.

Authors : Zhang X; State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210093, China. ; Chang H

Subjects: Aromatase/Aromatase/Aromatase/*metabolism ; Aromatase Inhibitors/Aromatase Inhibitors/Aromatase Inhibitors/*toxicity ; Endocrine Disruptors/Endocrine Disruptors/Endocrine Disruptors/*toxicity

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2011 Jun; Vol. 121 (2), pp. 320-7. Date of Electronic Publication: 2011 Apr 06.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn.

Authors : Bertalan R; Second Department of Medicine, Semmelweis University, Budapest, Hungary.; Csabay L

Subjects: Pregnancy Complications*; Aromatase/Aromatase/Aromatase/*metabolism ; Hyperandrogenism/Hyperandrogenism/Hyperandrogenism/*complications

Source: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2007 Oct; Vol. 23 (10), pp. 581-3.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8807913 Publication Model: Print Cited Medium: Print ISSN: 0951-3590

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Academic Journal

HPMA copolymer-aminoglutethimide conjugates inhibit aromatase in MCF-7 cell lines.

Authors : Greco F; Welsh School of Pharmacy, Redwood Building, Cardiff University, Tenovus Centre for Cancer Research, King Edward VII Avenue, UK.; Vicent MJ

Subjects: Acrylamides/Acrylamides/Acrylamides/*pharmacology ; Aminoglutethimide/Aminoglutethimide/Aminoglutethimide/*pharmacology ; Aromatase/Aromatase/Aromatase/*drug effects

Source: Journal of drug targeting [J Drug Target] 2005 Sep-Nov; Vol. 13 (8-9), pp. 459-70.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9312476 Publication Model: Print Cited Medium: Print ISSN: 1061-186X

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Academic Journal

Melatonin modulates aromatase activity in MCF-7 human breast cancer cells.

Authors : Cos S; Department of Physiology and Pharmacology, School of Medicine, University of Cantabria, Santander, Spain.; Martínez-Campa C

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Aromatase/Aromatase/Aromatase/*metabolism ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*drug therapy

Source: Journal of pineal research [J Pineal Res] 2005 Mar; Vol. 38 (2), pp. 136-42.Publisher: Wiley Country of Publication: England NLM ID: 8504412 Publication Model: Print Cited Medium: Print ISSN: 0742-3098 (Print) Linking

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Academic Journal

2- and 3-[(aryl)(azolyl)methyl]indoles as potential non-steroidal aromatase inhibitors.

Authors : Lézé MP; Laboratoires de Chimie Organique et de Chimie Thérapeutique, UPRES EA 1155, Faculté de Pharmacie, F-44035 Nantes, France.; Le Borgne M

Subjects: Aromatase/Aromatase/Aromatase/*drug effects ; Aromatase Inhibitors/Aromatase Inhibitors/Aromatase Inhibitors/*pharmacology ; Indoles/Indoles/Indoles/*pharmacology

Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2004 Dec; Vol. 19 (6), pp. 549-57.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Print ISSN: 1475-6366

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نتائج البحث

فلترة النتائج

Charged Amino Acids in the Transmembrane Helix Strongly Affect the Enzyme Activity of Aromatase.

A Dehydrogenase Dual Hydrogen Abstraction Mechanism Promotes Estrogen Biosynthesis: Can We Expand the Functional Annotation of the Aromatase Enzyme?

Modulation of expression of 17-Hydroxylase/17,20 lyase (CYP17) and P450 aromatase (CYP19) by inhibition of MEK1 in a human ovarian granulosa-like tumor cell line.

Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia.

Aromatase overexpression induces malignant changes in estrogen receptor α negative MCF-10A cells.

Bisphenol A disrupts steroidogenesis in human H295R cells.

Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn.

HPMA copolymer-aminoglutethimide conjugates inhibit aromatase in MCF-7 cell lines.

Melatonin modulates aromatase activity in MCF-7 human breast cancer cells.

2- and 3-[(aryl)(azolyl)methyl]indoles as potential non-steroidal aromatase inhibitors.

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