نتائج البحث

In Vitro and In Silico Anti-Glioblastoma Activity of Hydroalcoholic Extracts of Artemisia annua L. and Artemisia vulgaris L.

• Authors : Bernatoniene J; Department of Drug Technology and Social Pharmacy, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukileliu pr. 13, LT-50161 Kaunas, Lithuania.; Institute of Pharmaceutical Technologies, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukileliu pr. 13, LT-50161 Kaunas, Lithuania.

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 May 23; Vol. 29 (11). Date of Electronic Publication: 2024 May 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

تفاصيل العنوان

Polyploidy Promotes Hypertranscription, Apoptosis Resistance, and Ciliogenesis in Cancer Cells and Mesenchymal Stem Cells of Various Origins: Comparative Transcriptome In Silico Study.

• Authors : Anatskaya OV; Institute of Cytology Russian Academy of Sciences, 194064 St. Petersburg, Russia.; Vinogradov AE

Subjects: Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/cytology ; Polyploidy*

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 10; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies.

• Authors : Elkady H; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.; Elwan A

Subjects: Drug Design*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

• Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 397-410.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

تفاصيل العنوان

Novel sulphonamide-bearing methoxyquinazolinone derivatives as anticancer and apoptosis inducers: synthesis, biological evaluation and in silico studies.

• Authors : Alqahtani AS; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.; Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Subjects: Molecular Docking Simulation*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

• Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 86-99.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

تفاصيل العنوان

In vitro and in silico investigations of the pro-apoptotic activity of Opuntia ficus-indica cladode extracts against K562 cells

• Authors : Öncül Şule; Becer Eda; Mega Tiber Pınar

Subjects: opuntia ficus-indica; cancer; extract

• Source: Türk Biyokimya Dergisi, Vol 49, Iss 4, Pp 533-541 (2024)

تفاصيل العنوان

In Silico Identification and Validation of Cuproptosis-Related LncRNA Signature as a Novel Prognostic Model and Immune Function Analysis in Colon Adenocarcinoma.

• Authors : Wang Y; State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.; Huang X

Subjects: Adenocarcinoma*/Adenocarcinoma*/Adenocarcinoma*/pathology ; Colonic Neoplasms*/Colonic Neoplasms*/Colonic Neoplasms*/genetics ; Colonic Neoplasms*/Colonic Neoplasms*/Colonic Neoplasms*/pathology

• Source: Current oncology (Toronto, Ont.) [Curr Oncol] 2022 Sep 15; Vol. 29 (9), pp. 6573-6593. Date of Electronic Publication: 2022 Sep 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 9502503 Publication Model: Electronic Cited Medium: Internet ISSN: 1718-7729

تفاصيل العنوان

Thymol Protects against 5-Fluorouracil-Induced Hepatotoxicity via the Regulation of the Akt/GSK-3β Pathway in In Vivo and In Silico Experimental Models.

• Authors : Mahran, Yasmen F.¹ (AUTHOR) ; Badr, Amira M.² (AUTHOR) ; Al-Kharashi, Layla A.² (AUTHOR)

• Source: Pharmaceuticals (14248247). Aug2024, Vol. 17 Issue 8, p1094. 19p.

تفاصيل العنوان

In silico and in vitro analyses to investigate the effects of vitamin C on VEGF protein

• Authors : Azra Sakhawat, MPhil; Sana Javaid Awan, PhD; Muhammad Umer Khan, PhD

Subjects: Apoptosis; Cell cycle; Gene upregulation

• Source: Journal of Taibah University Medical Sciences, Vol 19, Iss 4, Pp 775-789 (2024)

تفاصيل العنوان

β-Caryophyllene promotes oxidative stress and apoptosis in KB cells through activation of mitochondrial-mediated pathway - An in-vitro and in-silico study.

• Authors : Ramachandhiran D; Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, India.; Sankaranarayanan C

Subjects: Apoptosis* ; Mitochondria* ; Oxidative Stress*

• Source: Archives of physiology and biochemistry [Arch Physiol Biochem] 2022 Feb; Vol. 128 (1), pp. 148-162. Date of Electronic Publication: 2019 Oct 04.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9510153 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies.

• Authors : Alanazi MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.; Alaa E

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

• Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 1732-1750.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

تفاصيل العنوان