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BCCIP promotes resistance of gastric cancer to cisplatin by modulating DNA damage repair pathways.

• Authors : JIA Zhe¹; ZENG Guangyan¹; ZOU Peng^1,2

• Source: Chinese Journal of Pathophysiology. May2025, Vol. 41 Issue 5, p871-881. 11p.

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A novel oral inhibitor for one-carbon metabolism and checkpoint kinase 1 inhibitor as a rational combination treatment for breast cancer

• Authors : Jin Lee; Xiaoxi Chen; Yuming Wang

Subjects: Methylenetetrahydrofolate Dehydrogenase (NADP); Mice, Knockout; 0301 basic medicine

• Source: Biochemical and Biophysical Research Communications. 584:7-14

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Inhibition of CHK 1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension

• Authors : Bourgeois, Alice; Bonnet, Sébastien; Breuils-Bonnet, Sandra ...

Subjects: Male; Pulmonary Arterial Hypertension; [SDV]Life Sciences [q-bio]

• Source: Arteriosclerosis, Thrombosis, and Vascular BiologyArteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2019, 39 (8), pp.1667-1681. ⟨10.1161/ATVBAHA.119.312537⟩

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Fms-like tyrosine kinase 3-internal tandem duplications epigenetically activates checkpoint kinase 1 in acute myeloid leukemia cells

• Authors : Lingli Yuan; Yudong Zhang

Subjects: Adult; Male; Chromatin Immunoprecipitation

• Source: Sci RepScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

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Inhibition of checkpoint kinase 1 potentiates anticancer activity of gemcitabine in bladder cancer cells

• Authors : Takako Asano; Akinori Sato; Kazuki Okubo

Subjects: Antimetabolites, Antineoplastic; Cell Survival; Science

• Source: Sci RepScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)

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Inhibition of Checkpoint Kinase 1 (CHK1) Upregulates Interferon Regulatory Factor 1 (IRF1) to Promote Apoptosis and Activate Anti-Tumor Immunity via MICA in Hepatocellular Carcinoma (HCC).

• Authors : Li, Xicai¹ (AUTHOR); Huang, Jingquan¹ (AUTHOR); Wu, Qiulin¹ (AUTHOR)

• Source: Cancers. Feb2023, Vol. 15 Issue 3, p850. 15p.

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Checkpoint kinase 1 is essential for fetal and adult hematopoiesis

• Authors : Miriam Erlacher; Georg Häcker; Sehar Afreen

Subjects: Mice, Knockout; 0301 basic medicine; Benzodiazepinones

• Source: EMBO Rep

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Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis

• Authors : Fabian Schuler; Johannes G. Weiss; Silke E. Lindner

Subjects: 0301 basic medicine; Lymphoma; Carcinogenesis

• Source: Nat CommunNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

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Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

• Authors : Andrea Griesinger; Eric Prince; Ilango Balakrishnan

Subjects: Benzodiazepinones; Cell Survival; Genes, myc

• Source: Oncotarget

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Checkpoint Kinase 1 Pharmacological Inhibition Synergizes with DNA-Damaging Agents and Overcomes Platinum Resistance in Basal-Like Breast Cancer

• Authors : Cristina Nieto-Jimenez; Ana Alcaraz-Sanabria; Sandra Martinez-Canales ...

Subjects: chemotherapy resistance; Synthetic lethality; platinum compounds

• Source: Int J Mol SciDigital.CSIC. Repositorio Institucional del CSICinstnameRepositorio Institucional de la Consejería de Sanidad de la Comunidad de MadridConsejería de Sanidad de

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