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Exploring the potential of gemcitabine-metal-organic frameworks in combating pancreatic cancer under ketogenic conditions.

• Authors : Nekoufar S; Department of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.; Ghorbani M

Subjects: Gemcitabine* ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/analogs & derivatives ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/pharmacology

• Source: BMC cancer [BMC Cancer] 2025 Jan 09; Vol. 25 (1), pp. 53. Date of Electronic Publication: 2025 Jan 09.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Vinpocetine attenuates methotrexate-induced hippocampal intoxication via Keap-1/Nrf2, NF-κB/AP-1, and apoptotic pathways in rats.

• Authors : Alghamdi B; Department of Physiology, Neuroscience Unit, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.; Neuroscience and Geroscience Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Subjects: Methotrexate*/Methotrexate*/Methotrexate*/toxicity ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Vinca Alkaloids*/Vinca Alkaloids*/Vinca Alkaloids*/pharmacology

• Source: Drug and chemical toxicology [Drug Chem Toxicol] 2024 Nov; Vol. 47 (6), pp. 1038-1049. Date of Electronic Publication: 2024 Mar 20.Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 7801723 Publication Model: Print-Electronic Cited Medium: Internet

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The synergistic effect of miR-203 and cytarabine on the inhibition of cell proliferation and induction of apoptosis in chronic myelogenous leukemia cells.

• Authors : Qi S; Department of Oncology, Shijiazhuang Traditional Chinese Medicine Hospital, ShiJiaZhuang, HeBei, China.; Huang J

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

• Source: Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2024 Sep; Vol. 37 (5), pp. 1019-1025.Publisher: Faculty of Pharmacy, University of Karachi Country of Publication: Pakistan NLM ID: 9426356 Publication Model: Print Cited Medium: Internet

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Anticancer Strategy Targeting Cell Death Regulators: Switching the Mechanism of Anticancer Floxuridine-Induced Cell Death from Necrosis to Apoptosis.

• Authors : Sato A; Department of Biochemistry and Molecular Biology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.; Hiramoto A

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Floxuridine/Floxuridine/Floxuridine/*pharmacology

• Source: International journal of molecular sciences [Int J Mol Sci] 2020 Aug 16; Vol. 21 (16). Date of Electronic Publication: 2020 Aug 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Multidose 5-Fluorouracil is Highly Toxic to Growing Ovarian Follicles in Mice.

• Authors : Stringer JM; Ovarian Biology Laboratory, Department of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.; Swindells EOK

Subjects: DNA Damage*; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*toxicity ; Apoptosis/Apoptosis/Apoptosis/*drug effects

• Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2018 Nov 01; Vol. 166 (1), pp. 97-107.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN:

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Gemcitabine induces apoptosis and autophagy via the AMPK/mTOR signaling pathway in pancreatic cancer cells.

• Authors : Zhu J; Department of General Surgery and Laparoscopic Center, Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, People's Republic of China.; Chen Y

Subjects: Adenylate Kinase/Adenylate Kinase/Adenylate Kinase/*metabolism ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

• Source: Biotechnology and applied biochemistry [Biotechnol Appl Biochem] 2018 Sep; Vol. 65 (5), pp. 665-671. Date of Electronic Publication: 2018 Apr 16.Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8609465 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Metabolic Heterogeneity in Diffuse Large B-Cell Lymphoma Cells Reveals an Innovative Antimetabolic Combination Strategy.

• Authors : Lordello, Leonardo¹ (AUTHOR) ; Nuan-Aliman, Stéphanie¹ (AUTHOR) ; Kielbassa-Elkadi, Karoline¹ (AUTHOR)

• Source: Cancers. Feb2025, Vol. 17 Issue 3, p394. 19p.

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Protective Effects of Cereal-Based Fermented Beverages Against 5-Fluorouracil-Induced Intestinal Damage in Mice.

• Authors : Qin, Dongze¹ ; Fu, Wenhui¹ ; Sun, Yi¹

Subjects: *THERAPEUTIC use of antineoplastic agents; *BIOLOGICAL models; *MUCOSITIS

• Source: Nutrients. Dec2024, Vol. 16 Issue 24, p4332. 19p.

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Translational control of Bcl-2 promotes apoptosis of gastric carcinoma cells.

• Authors : Tao S; Oncology Department, Xin Hua Hospital affiliated To Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China.; Gu J

Subjects: Apoptosis* ; Gene Expression Regulation, Neoplastic*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism

• Source: BMC cancer [BMC Cancer] 2021 Jan 05; Vol. 21 (1), pp. 12. Date of Electronic Publication: 2021 Jan 05.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death.

• Authors : Morgan JA; Departments of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105.; Lynch J

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Apoptosomes/Apoptosomes/Apoptosomes/*metabolism

• Source: Scientific reports [Sci Rep] 2015 Nov 18; Vol. 5, pp. 16488. Date of Electronic Publication: 2015 Nov 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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