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  • 1-10 ل  1,640 نتائج ل ""Protease Inhibitors""

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Subject : antiviral agents
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Academic Journal

Breaking the Chain: Protease Inhibitors as Game Changers in Respiratory Viruses Management.

  • Authors : Papaneophytou C; Department of Life Sciences, School of Life and Health Sciences, University of Nicosia, Nicosia 2417, Cyprus.

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; Respiratory Tract Infections*/Respiratory Tract Infections*/Respiratory Tract Infections*/drug therapy ; Respiratory Tract Infections*/Respiratory Tract Infections*/Respiratory Tract Infections*/virology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 25; Vol. 25 (15). Date of Electronic Publication: 2024 Jul 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.

  • Authors : Costacurta F; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.; Dodaro A

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; Drug Resistance, Viral*/Drug Resistance, Viral*/Drug Resistance, Viral*/genetics SARS-CoV-2 variants

  • Source: PLoS pathogens [PLoS Pathog] 2024 Sep 11; Vol. 20 (9), pp. e1012522. Date of Electronic Publication: 2024 Sep 11 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Recent Advances in SARS-CoV-2 Main Protease Inhibitors: From Nirmatrelvir to Future Perspectives.

  • Authors : Citarella A; Department of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy.; Dimasi A

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/enzymology ; COVID-19 Drug Treatment*

  • Source: Biomolecules [Biomolecules] 2023 Sep 02; Vol. 13 (9). Date of Electronic Publication: 2023 Sep 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Inhibitors of SARS-CoV-2 Main Protease (Mpro) as Anti-Coronavirus Agents.

  • Authors : Zagórska A; Department of Medicinal Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.; Czopek A

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/enzymology ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology

  • Source: Biomolecules [Biomolecules] 2024 Jul 04; Vol. 14 (7). Date of Electronic Publication: 2024 Jul 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Screening of M pro Protease (SARS-CoV-2) Covalent Inhibitors from an Anthocyanin-Rich Blueberry Extract Using an HRMS-Based Analytical Platform.

  • Authors : Altomare A; Department of Pharmaceutical Sciences (DISFARM), Università degli Studi di Milano, Via Mangiagalli 25, 20133 Milan, Italy.; Baron G

Subjects: Blueberry Plants*/Blueberry Plants*/Blueberry Plants*/chemistry ; Anthocyanins*/Anthocyanins*/Anthocyanins*/pharmacology ; Anthocyanins*/Anthocyanins*/Anthocyanins*/chemistry

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jun 06; Vol. 29 (11). Date of Electronic Publication: 2024 Jun 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Shedding Light on Dark Chemical Matter: The Discovery of a SARS-CoV-2 M pro Main Protease Inhibitor through Intensive Virtual Screening and In Vitro Evaluation.

  • Authors : Peralta-Moreno MN; Department of Materials Science and Physical Chemistry, Institut de Recerca en Quimica Teòrica i Computacional (IQTCUB), University of Barcelona (UB), 08028 Barcelona, Spain.; Mena Y

Subjects: Molecular Docking Simulation* ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/enzymology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 01; Vol. 25 (11). Date of Electronic Publication: 2024 Jun 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Benzocarbazoledinones as SARS-CoV-2 Replication Inhibitors: Synthesis, Cell-Based Studies, Enzyme Inhibition, Molecular Modeling, and Pharmacokinetics Insights.

  • Authors : de Souza LG; Instituto de Pesquisa de Produtos Naturais, Universidade Federal do Rio de Janeiro, Ilha do Fundão, CCS, Bloco H-Sala H29, Rio de Janeiro 21941-902, RJ, Brazil.; Penna EA

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacokinetics

  • Source: Viruses [Viruses] 2024 Nov 13; Vol. 16 (11). Date of Electronic Publication: 2024 Nov 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

Miniaturized Modular Click Chemistry-enabled Rapid Discovery of Unique SARS-CoV-2 M pro Inhibitors With Robust Potency and Drug-like Profile.

  • Authors : Yang M; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Ji'nan, 250012, China.; Lee MK

Subjects: Click Chemistry*/Click Chemistry*/Click Chemistry*/methods ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov; Vol. 11 (43), pp. e2404884. Date of Electronic Publication: 2024 Sep 25.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

SARS-CoV-2 PL pro Inhibition: Evaluating in Silico Repurposed Fidaxomicin's Antiviral Activity Through In Vitro Assessment.

Subjects: Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/chemistry ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects

  • Source: ChemistryOpen [ChemistryOpen] 2024 Nov; Vol. 13 (11), pp. e202400091. Date of Electronic Publication: 2024 Aug 05.Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101594811 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Inhibition of NS2B/NS3 Protease: A New Therapeutic Opportunity to Treat Dengue and Zika Virus Infection.

  • Authors : Starvaggi J; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.; Previti S

Subjects: Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/therapeutic use ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology ; Dengue*/Dengue*/Dengue*/drug therapy

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 16; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 ل  1,640 نتائج ل ""Protease Inhibitors""