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  • 1-10 ل  88 نتائج ل ""Cytochrome P-450 CYP2D6""
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Academic Journal

Into a Deeper Understanding of CYP2D6's Role in Risperidone Monotherapy and the Potential Side Effects in Schizophrenia Spectrum Disorders.

  • Authors : Bondrescu M; Department of Neurosciences-Psychiatry, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.; Timis County Emergency Clinical Hospital 'Pius Brinzeu', Liviu Rebreanu 156, 300723 Timisoara, Romania.

Subjects: Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/metabolism ; Risperidone*/Risperidone*/Risperidone*/adverse effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 08; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Challenging pharmacotherapy management of a psychotic disorder due to a delicate pharmacogenetic profile and drug-drug interactions: a case report and literature review.

Subjects: Drug Interactions* ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/administration & dosage ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/therapeutic use

  • Source: Croatian medical journal [Croat Med J] 2024 Aug 31; Vol. 65 (4), pp. 383-395.Publisher: Medicinska Naklada Country of Publication: Croatia NLM ID: 9424324 Publication Model: Print Cited Medium: Internet ISSN: 1332-8166

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Academic Journal

Phenoconversion of CYP2D6 by inhibitors modifies aripiprazole exposure.

  • Authors : Kiss Á; Research Centre for Natural Sciences, Institute of Enzymology, Hungarian Academy of Sciences, Magyar Tudósok 2, Budapest, 1117, Hungary.; Menus Á

Subjects: Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/metabolism; Antipsychotic Agents/Antipsychotic Agents/Antipsychotic Agents/*pharmacology

  • Source: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2020 Feb; Vol. 270 (1), pp. 71-82. Date of Electronic Publication: 2019 Jan 02.Publisher: Springer International Country of Publication: Germany NLM ID: 9103030 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

CYP1A2 expression rather than genotype is associated with olanzapine concentration in psychiatric patients.

  • Authors : Fekete F; Institute of Enzymology, HUN-REN Research Centre for Natural Sciences, Magyar tudósok 2, Budapest, 1117, Hungary.; Doctoral School of Biology and Institute of Biology, Eötvös Loránd University, Pázmány Péter Sétány 1/A, Budapest, 1117, Hungary.

Subjects: Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/genetics ; Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/metabolism ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/adverse effects

  • Source: Scientific reports [Sci Rep] 2023 Oct 28; Vol. 13 (1), pp. 18507. Date of Electronic Publication: 2023 Oct 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovering interactions in augmentation strategies: Impact of duloxetine on the metabolism of aripiprazole.

  • Authors : Margraff T; Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital RWTH Aachen, Aachen, Germany.; JARA-Translational Brain Medicine, RWTH Aachen University, Aachen, Germany.

Subjects: Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/pharmacology ; Quinolones*/Quinolones*/Quinolones*/pharmacokinetics; Humans

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2023 Jul; Vol. 133 (1), pp. 73-81. Date of Electronic Publication: 2023 May 04.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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Academic Journal

Therapeutic Reference Range for Aripiprazole in Schizophrenia Revised: a Systematic Review and Metaanalysis.

  • Authors : Hart XM; Department of Molecular Neuroimaging, Medical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany. .; Arbeitsgemeinschaft Für Neuropsychopharmakologie Und Pharmakopsychiatrie (AGNP), Work group Therapeutic Drug Monitoring, München, Germany. .

Subjects: Schizophrenia*/Schizophrenia*/Schizophrenia*/chemically induced ; Antipsychotic Agents*/Antipsychotic Agents*/Antipsychotic Agents*/adverse effects; Humans

  • Source: Psychopharmacology [Psychopharmacology (Berl)] 2022 Nov; Vol. 239 (11), pp. 3377-3391. Date of Electronic Publication: 2022 Oct 05.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Influence of CYP2D6, CYP3A4, CYP3A5 and ABCB1 Polymorphisms on Pharmacokinetics and Safety of Aripiprazole in Healthy Volunteers.

  • Authors : Belmonte C; Clinical Pharmacology Department, Hospital Universitario de la Princesa, Instituto Teofilo Hernando, Instituto de Investigacion Sanitaria Princesa (IP), Madrid, Spain.; UICEC Hospital Universitario de la Princesa, Plataforma SCReN (Spanish Clinical Reseach Network), Instituto de Investigacion Sanitaria la Princesa (IP), Madrid, Spain.

Subjects: Antipsychotic Agents/Antipsychotic Agents/Antipsychotic Agents/*pharmacokinetics ; Aripiprazole/Aripiprazole/Aripiprazole/*pharmacokinetics ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*genetics

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2018 Jun; Vol. 122 (6), pp. 596-605. Date of Electronic Publication: 2018 Feb 22.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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Academic Journal

CYP2D6-inhibiting drugs and risk of fall injuries after newly initiated antidepressant and antipsychotic therapy in a Swedish, register-based case-crossover study.

  • Authors : Dahl ML; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Leander K

Subjects: Accidental Falls* ; Registries*; Antidepressive Agents/Antidepressive Agents/Antidepressive Agents/*adverse effects

  • Source: Scientific reports [Sci Rep] 2021 Mar 11; Vol. 11 (1), pp. 5796. Date of Electronic Publication: 2021 Mar 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The effect of perazine on the CYP2D6 and CYP2C19 phenotypes as measured by the dextromethorphan and mephenytoin tests in psychiatric patients.

  • Authors : Baumann P; Department of Psychiatry (DP-CHUV), University of Lausanne, Prilly-Lausanne, Switzerland.; Eap CB

Subjects: Antipsychotic Agents/Antipsychotic Agents/Antipsychotic Agents/*pharmacology ; Cytochrome P-450 CYP2C19/Cytochrome P-450 CYP2C19/Cytochrome P-450 CYP2C19/*metabolism ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*metabolism

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2020 May; Vol. 126 (5), pp. 444-447. Date of Electronic Publication: 2019 Dec 19.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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Academic Journal

Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone.

  • Authors : Hongkaew Y; Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.; Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand.

Subjects: Antipsychotic Agents/Antipsychotic Agents/Antipsychotic Agents/*therapeutic use ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*genetics ; Risperidone/Risperidone/Risperidone/*therapeutic use

  • Source: Scientific reports [Sci Rep] 2021 Feb 18; Vol. 11 (1), pp. 4158. Date of Electronic Publication: 2021 Feb 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  88 نتائج ل ""Cytochrome P-450 CYP2D6""