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Academic Journal

Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.

  • Authors : Dong RF; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.; Qin CJ

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology

  • Source: British journal of pharmacology [Br J Pharmacol] 2025 May; Vol. 182 (10), pp. 2287-2309. Date of Electronic Publication: 2023 Jul 12.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

The Assessment of the Effect of Autophagy Inhibitors-Chloroquine and 3-Methyladenine on the Antitumor Activity of Trametinib Against Amelanotic Melanoma Cells.

  • Authors : Stencel D; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 4 Jagiellońska Str., 41-200 Sosnowiec, Poland.; Kowalska J

Subjects: Pyridones*/Pyridones*/Pyridones*/pharmacology ; Pyridones*/Pyridones*/Pyridones*/therapeutic use ; Autophagy*/Autophagy*/Autophagy*/drug effects

  • Source: Cells [Cells] 2025 Apr 07; Vol. 14 (7). Date of Electronic Publication: 2025 Apr 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

A Comprehensive Review of Nanoparticle-Based Drug Delivery for Modulating PI3K/AKT/mTOR-Mediated Autophagy in Cancer.

  • Authors : Rahman MA; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA.; Jalouli M

Subjects: TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; Autophagy*/Autophagy*/Autophagy*/drug effects ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Feb 21; Vol. 26 (5). Date of Electronic Publication: 2025 Feb 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Quinalizarin induces autophagy, apoptosis and mitotic catastrophe in cervical and prostate cancer cells.

  • Authors : Trybus W; Department of Medical Biology, Jan Kochanowski University of Kielce, Uniwersytecka 7, Kielce, 25-406, Poland. .; Trybus E

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Autophagy*/Autophagy*/Autophagy*/drug effects ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/pathology

  • Source: Scientific reports [Sci Rep] 2025 Feb 12; Vol. 15 (1), pp. 5252. Date of Electronic Publication: 2025 Feb 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Anti-Cancer Strategy Based on Changes in the Role of Autophagy Depending on the Survival Environment and Tumorigenesis Stages.

  • Authors : Lee M; Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.; Institute for New Drug Development, Incheon National University, Incheon 22012, Republic of Korea.

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; Neoplasms*/Neoplasms*/Neoplasms*/pathology ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Oct 30; Vol. 29 (21). Date of Electronic Publication: 2024 Oct 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Blockage of Autophagy for Cancer Therapy: A Comprehensive Review.

  • Authors : Hassan AMIA; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao SAR 999078, China.; Zhao Y

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 07; Vol. 25 (13). Date of Electronic Publication: 2024 Jul 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Cross-Talk Between Selenium Nanoparticles and Cancer Treatment Through Autophagy.

  • Authors : Ali W; College of Veterinary Medicine, Yangzhou University Yangzhou, Yangzhou, Jiangsu, 225009, People's Republic of China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, 225009, People's Republic of China.

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; Selenium*/Selenium*/Selenium*/chemistry ; Selenium*/Selenium*/Selenium*/pharmacology

  • Source: Biological trace element research [Biol Trace Elem Res] 2024 Jul; Vol. 202 (7), pp. 2931-2940. Date of Electronic Publication: 2023 Oct 10.Publisher: Humana Press Country of Publication: United States NLM ID: 7911509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

ER-phagy mediates the anti-tumoral synergism between HDAC inhibition and chemotherapy.

  • Authors : Gössl FJ; Clinic of Gastroenterology, Endocrinology and Metabolism, Center for Tumor- and Immune Biology, Philipps University Marburg, Hans-Meerwein-Str. 3, Marburg, 35043, Germany.; Polo P

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/therapeutic use ; Autophagy*/Autophagy*/Autophagy*/drug effects

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2025 Apr 26; Vol. 23 (1), pp. 202. Date of Electronic Publication: 2025 Apr 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

Mechanical forces inducing oxaliplatin resistance in pancreatic cancer can be targeted by autophagy inhibition.

  • Authors : Kalli M; Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus. .; Mpekris F

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Oxaliplatin*/Oxaliplatin*/Oxaliplatin*/therapeutic use ; Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/drug effects

  • Source: Communications biology [Commun Biol] 2024 Nov 27; Vol. 7 (1), pp. 1581. Date of Electronic Publication: 2024 Nov 27.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effects of Reduced Extracellular Sodium Concentrations on Cisplatin Treatment in Human Tumor Cells: The Role of Autophagy.

  • Authors : Naldi L; Endocrinology, Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', Careggi University Hospital, University of Florence, 50139 Florence, Italy.; Fibbi B

Subjects: Cisplatin*/Cisplatin*/Cisplatin*/pharmacology ; Autophagy*/Autophagy*/Autophagy*/drug effects ; Sodium*/Sodium*/Sodium*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 16; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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