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  • 1-10 ل  517 نتائج ل ""Triazines""

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Subject : antineoplastic agents
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Academic Journal

Structure optimization and molecular dynamics studies of new tumor-selective s -triazines targeting DNA and MMP-10/13 for halting colorectal and secondary liver cancers.

  • Authors : Morcos CA; Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt.; Haiba NS

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemical synthesis

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2423174. Date of Electronic Publication: 2024 Nov 08.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The activity of pyrazolo[4,3- e ][1,2,4]triazine and pyrazolo[4,3- e ]tetrazolo[1,5- b ][1,2,4]triazine sulphonamide derivatives in monolayer and spheroid breast cancer cell cultures.

  • Authors : Szymanowska A; Department of Biotechnology, Medical University of Bialystok, Bialystok, Poland.; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Subjects: Triazines*/Triazines*/Triazines*/pharmacology ; Triazines*/Triazines*/Triazines*/chemistry ; Triazines*/Triazines*/Triazines*/chemical synthesis

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2343352. Date of Electronic Publication: 2024 May 03.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

In Vitro, In Vivo, Ex Vivo Characterisation of Dihydroimidazotriazinones and Their Thermal Decomposition Course Studied by Coupled and Simultaneous Thermal Analysis Methods.

  • Authors : Worzakowska M; Department of Polymer Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University in Lublin, 33 Gliniana Street, 20-614 Lublin, Poland.; Sztanke M

Subjects: Zebrafish* ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jan 10; Vol. 26 (2). Date of Electronic Publication: 2025 Jan 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Characterization of Bozitinib as a potential therapeutic agent for MET-amplified gastric cancer.

  • Authors : Lin H; Department of Oncology, NHC Key Laboratory of Cancer Proteomics & State Local Joint Engineering Laboratory for Anticancer Drugs, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.; Qu L

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/drug therapy ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/metabolism

  • Source: Communications biology [Commun Biol] 2025 Jan 28; Vol. 8 (1), pp. 134. Date of Electronic Publication: 2025 Jan 28.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX.

  • Authors : Zain-Alabdeen AI; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, El Giesh Street, Tanta, 31527, Egypt. .; El-Moselhy TF

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy; Antigens, Neoplasm/Antigens, Neoplasm/Antigens, Neoplasm/metabolism

  • Source: Scientific reports [Sci Rep] 2022 Oct 06; Vol. 12 (1), pp. 16756. Date of Electronic Publication: 2022 Oct 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pyrazolo[4,3- e ]tetrazolo[1,5- b ][1,2,4]triazine Sulfonamides as an Important Scaffold for Anticancer Drug Discovery-In Vitro and In Silico Evaluation.

  • Authors : Kciuk M; Department of Molecular Biotechnology and Genetics, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland.; Doctoral School of Exact and Natural Sciences, University of Lodz, Banacha Street 12/16, 90-237 Lodz, Poland.

Subjects: Triazines*/Triazines*/Triazines*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology; Cell Line, Tumor

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 30; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Pyrazolo[4,3- e ]tetrazolo[1,5- b ][1,2,4]triazine Sulfonamides as Novel Potential Anticancer Agents: Cytotoxic and Genotoxic Activities In Vitro.

  • Authors : Bukowski K; Department of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 12/16 Banacha St., 90-237 Lodz, Poland.; Marciniak B

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Triazines*/Triazines*/Triazines*/chemistry ; Triazines*/Triazines*/Triazines*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2022 Jun 11; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

New 2-[(4-Amino-6- N -substituted-1,3,5-triazin-2-yl)methylthio]- N -(imidazolidin-2-ylidene)-4-chloro-5-methylbenzenesulfonamide Derivatives, Design, Synthesis and Anticancer Evaluation.

  • Authors : Tomorowicz Ł; Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland.; Żołnowska B

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Benzenesulfonates*/Benzenesulfonates*/Benzenesulfonates*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jun 28; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Discovery of novel enasidenib analogues targeting inhibition of mutant isocitrate dehydrogenase 2 as antileukaemic agents.

  • Authors : Khalil AF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.; El-Moselhy TF

Subjects: Isocitrate Dehydrogenase*/Isocitrate Dehydrogenase*/Isocitrate Dehydrogenase*/genetics ; Isocitrate Dehydrogenase*/Isocitrate Dehydrogenase*/Isocitrate Dehydrogenase*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2157411.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Exploration of novel heterofused 1,2,4-triazine derivative in colorectal cancer.

  • Authors : Hermanowicz JM; Department of Pharmacodynamics, Medical University of Bialystok, Bialystok, Poland.; Department of Clinical Pharmacy, Medical University of Bialystok, Bialystok, Poland.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*drug therapy ; Triazines/Triazines/Triazines/*pharmacology

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 535-548.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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  • 1-10 ل  517 نتائج ل ""Triazines""