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  • 1-10 ل  1,479 نتائج ل ""Cell Cycle Checkpoints""

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Subject : antineoplastic agents
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Academic Journal

Evaluation of newly synthesized 2-(thiophen-2-yl)-1H-indole derivatives as anticancer agents against HCT-116 cell proliferation via cell cycle arrest and down regulation of miR-25.

  • Authors : Abdelazeem NM; Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki, 12622, Cairo, Egypt.; Gouhar SA

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: Scientific reports [Sci Rep] 2024 Aug 29; Vol. 14 (1), pp. 20045. Date of Electronic Publication: 2024 Aug 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A Novel Pyrazole Exhibits Potent Anticancer Cytotoxicity via Apoptosis, Cell Cycle Arrest, and the Inhibition of Tubulin Polymerization in Triple-Negative Breast Cancer Cells.

  • Authors : Borrego EA; The Border Biomedical Research Center, The University of Texas El Paso, El Paso, TX 79968, USA.; Department of Biological Sciences, The University of Texas El Paso, El Paso, TX 79968, USA.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism

  • Source: Cells [Cells] 2024 Jul 20; Vol. 13 (14). Date of Electronic Publication: 2024 Jul 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Anticancer Effects of Mitoquinone via Cell Cycle Arrest and Apoptosis in Canine Mammary Gland Tumor Cells.

  • Authors : Lee R; Department of Livestock, Korea National University of Agriculture and Fisheries, Jeonju-si 54874, Republic of Korea.; Department of Animal Biotechnology, College of Life Science, Sangji University, Wonju-si 26339, Republic of Korea.

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/drug therapy ; Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 30; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Identification of 3-Aryl-1-benzotriazole-1-yl-acrylonitrile as a Microtubule-Targeting Agent (MTA) in Solid Tumors.

  • Authors : Zoroddu S; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.; Sanna L

Subjects: Microtubules*/Microtubules*/Microtubules*/drug effects ; Microtubules*/Microtubules*/Microtubules*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 24; Vol. 25 (11). Date of Electronic Publication: 2024 May 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Synthesis, bioactivity assessment, molecular docking and ADMET studies of new chromone congeners exhibiting potent anticancer activity.

  • Authors : Abo-Salem HM; Chemistry of Natural Compounds Department, National Research Centre, Dokki, Giza, 12622, Egypt. .; El Souda SSM

Subjects: Molecular Docking Simulation* ; Chromones*/Chromones*/Chromones*/chemistry ; Chromones*/Chromones*/Chromones*/pharmacology

  • Source: Scientific reports [Sci Rep] 2024 Apr 26; Vol. 14 (1), pp. 9636. Date of Electronic Publication: 2024 Apr 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Antitumoral Activity of the Universal Methyl Donor S -Adenosylmethionine in Glioblastoma Cells.

  • Authors : Mosca L; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Via Luigi De Crecchio 7, 80138 Naples, Italy.; Pagano C

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 10; Vol. 29 (8). Date of Electronic Publication: 2024 Apr 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

JIB-04, a Pan-Inhibitor of Histone Demethylases, Targets Histone-Lysine-Demethylase-Dependent AKT Pathway, Leading to Cell Cycle Arrest and Inhibition of Cancer Stem-Like Cell Properties in Hepatocellular Carcinoma Cells.

  • Authors : Lee J; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.; BK21 Yonsei Education & Research Center for Biosystems, Yonsei University, Seoul 120-749, Korea.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/drug therapy

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 11; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Design, synthesis and biological evaluation of 2-((4-sulfamoylphenyl)amino)-pyrrolo[2,3-d]pyrimidine derivatives as CDK inhibitors.

  • Authors : Yang B; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.; Quan Y

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy; Humans

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2169282.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Synthesis and Biological Evaluation of Benzo [4,5]- and Naphtho[2',1':4,5]imidazo[1,2-c]pyrimidinone Derivatives.

  • Authors : Kamzeeva P; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Dagaev N

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy; Animals

  • Source: Biomolecules [Biomolecules] 2023 Nov 20; Vol. 13 (11). Date of Electronic Publication: 2023 Nov 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Nucleoside analogs as a radiosensitizer modulating DNA repair, cell cycle checkpoints, and apoptosis.

  • Authors : Yasui H; Laboratory of Radiation Biology, Department of Applied Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.; Iizuka D

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cell Cycle Checkpoints/Cell Cycle Checkpoints/Cell Cycle Checkpoints/*drug effects

  • Source: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2020; Vol. 39 (1-3), pp. 439-452. Date of Electronic Publication: 2019 Sep 27.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 100892832 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  1,479 نتائج ل ""Cell Cycle Checkpoints""