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Academic Journal

Synthesis, molecular docking studies and biological evaluation of N-(4-oxo-2-(trifluoromethyl)-4H-chromen-7-yl) benzamides as potential antioxidant, and anticancer agents.

  • Authors : Jorepalli S; Department of Pharmaceutical Chemistry, Sri Padmavati Mahila Visva Vidyalayam, Tirupati, 517 502, India.; Department of Pharmaceutical Chemistry, P.R. Reddy Memorial College of Pharmacy, Kadapa, 516 003, India.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemical synthesis ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

  • Source: Scientific reports [Sci Rep] 2024 Apr 29; Vol. 14 (1), pp. 9866. Date of Electronic Publication: 2024 Apr 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design, synthesis, and cytotoxic activity of 2-amino-1,4-naphthoquinone-benzamide derivatives as apoptosis inducers.

  • Authors : Sayahi MH; Department of Chemistry, Payame Noor University, Tehran, Iran.; Hassani B

Subjects: Naphthoquinones*/Naphthoquinones*/Naphthoquinones*/pharmacology ; Naphthoquinones*/Naphthoquinones*/Naphthoquinones*/chemistry ; Naphthoquinones*/Naphthoquinones*/Naphthoquinones*/chemical synthesis

  • Source: Scientific reports [Sci Rep] 2024 Nov 08; Vol. 14 (1), pp. 27302. Date of Electronic Publication: 2024 Nov 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

HSP70 Is a Critical Regulator of HSP90 Inhibitor's Effectiveness in Preventing HCl-Induced Chronic Lung Injury and Pulmonary Fibrosis.

  • Authors : Colunga Biancatelli RML; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23509, USA.; Division of Pulmonary and Critical Care, Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA.

Subjects: Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/chemically induced ; Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/drug therapy ; Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 05; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Assessing the Efficacy of Anti-Cancer Drugs on Organoid Models Derived from Prostate Cancer.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/drug therapy ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/pathology

  • Source: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2023 Dec; Vol. 513 (Suppl 1), pp. S96-S99. Date of Electronic Publication: 2024 Feb 09.Publisher: Pleiades Publishing Country of Publication: United States NLM ID: 101126895 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Phase 1 trial of entinostat as monotherapy and combined with exemestane in Japanese patients with hormone receptor-positive advanced breast cancer.

  • Authors : Masuda N; Department of Surgery, Breast Oncology, National Hospital Organization Osaka National Hospital, Osaka, Japan. .; Present address: Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. .

Subjects: Androstadienes/Androstadienes/Androstadienes/*therapeutic use ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*therapeutic use

  • Source: BMC cancer [BMC Cancer] 2021 Nov 24; Vol. 21 (1), pp. 1269. Date of Electronic Publication: 2021 Nov 24.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

ISL1 promotes enzalutamide resistance in castration-resistant prostate cancer (CRPC) through epithelial to mesenchymal transition (EMT).

  • Authors : Choi JD; Department of Urology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Republic of Korea.; Kim TJ

Subjects: Androgen Antagonists/Androgen Antagonists/Androgen Antagonists/*therapeutic use ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Benzamides/Benzamides/Benzamides/*therapeutic use

  • Source: Scientific reports [Sci Rep] 2021 Nov 09; Vol. 11 (1), pp. 21984. Date of Electronic Publication: 2021 Nov 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Causal inferences and real-world evidence: A comparative effectiveness evaluation of abiraterone acetate against enzalutamide.

  • Authors : Johansson P; Department of Statistics, Uppsala University, Uppsala, Sweden.; Centre for Health-Economic Research, Uppsala University, Uppsala, Sweden.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/drug therapy; Male

  • Source: PloS one [PLoS One] 2023 Oct 26; Vol. 18 (10), pp. e0293000. Date of Electronic Publication: 2023 Oct 26 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Initial dose reduction of enzalutamide does not decrease the incidence of adverse events in castration-resistant prostate cancer.

  • Authors : Tsuzuki S; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.; Nakanishi S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage ; Benzamides/Benzamides/Benzamides/*administration & dosage ; Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/*epidemiology

  • Source: PloS one [PLoS One] 2021 Oct 01; Vol. 16 (10), pp. e0258160. Date of Electronic Publication: 2021 Oct 01 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Histone acetyltransferase 1 upregulates androgen receptor expression to modulate CRPC cell resistance to enzalutamide.

  • Authors : Hong Z; Department of Urology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.; Xiang Z

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Benzamides/Benzamides/Benzamides/*pharmacology ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects

  • Source: Clinical and translational medicine [Clin Transl Med] 2021 Jul; Vol. 11 (7), pp. e495.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Report

Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL.

  • Authors : Chen TL; Division of Hematology, Department of Internal Medicine, The Ohio State University, 462 OSUCCC, 410 W 12th Avenue, Columbus, OH, 43210, USA.; Harrington B

Subjects: Adenine/Adenine/Adenine/*analogs & derivatives ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Benzamides/Benzamides/Benzamides/*therapeutic use

  • Source: Journal of hematology & oncology [J Hematol Oncol] 2021 Feb 24; Vol. 14 (1), pp. 36. Date of Electronic Publication: 2021 Feb 24.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722

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