نتائج البحث

Phenylbenzohydrazides Obtained from Isatoic Anhydride Present Anti-Inflammatory Activity In Vivo and In Vitro.

• Authors : Paiva JPB; Laboratório de Farmacologia da Dor e da Inflamação, Programa de Pesquisa em Descoberta de Fármacos, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.; Cordeiro MS

Subjects: Nitric Oxide*/Nitric Oxide*/Nitric Oxide*/metabolism ; Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/pharmacology ; Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/therapeutic use

• Source: Biomolecules [Biomolecules] 2022 Dec 19; Vol. 12 (12). Date of Electronic Publication: 2022 Dec 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

تفاصيل العنوان

Antinociceptive and anti-inflammatory effects of hydrazone derivatives and their possible mechanism of action in mice.

• Authors : Medeiros MAMB; Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.; Pós-Graduação em Biotecnologia, Universidade Estadual de Feira de Santana, Feira de Santana, Bahia, Brasil.

Subjects: Analgesics/Analgesics/Analgesics/*pharmacology ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Hydrazones/Hydrazones/Hydrazones/*pharmacology

• Source: PloS one [PLoS One] 2021 Nov 24; Vol. 16 (11), pp. e0258094. Date of Electronic Publication: 2021 Nov 24 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Discovery of naphthyl-N-acylhydrazone p38α MAPK inhibitors with in vivo anti-inflammatory and anti-TNF-α activity.

• Authors : Freitas RHCN; Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Cordeiro NM

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*chemistry ; Hydrazones/Hydrazones/Hydrazones/*chemistry ; Mitogen-Activated Protein Kinase 14/Mitogen-Activated Protein Kinase 14/Mitogen-Activated Protein Kinase 14/*antagonists & inhibitors

• Source: Chemical biology & drug design [Chem Biol Drug Des] 2018 Feb; Vol. 91 (2), pp. 391-397. Date of Electronic Publication: 2017 Sep 10.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Inibição de Ciclooxigenases 1 (COX-1) e 2 (COX-2) por Monoterpenos: um Estudo in Silico.

• Authors : Romero, Rafaelle Bonzanini¹; Romero, Adriano Lopes¹

• Source: Unopar Cientifica Ciencias Biologicas e da Saude. 2014, Vol. 16 Issue 4, p307-316. 10p.

تفاصيل العنوان

3-Aminothiophene-2-acylhydrazones: non-toxic, analgesic and anti-inflammatory lead-candidates.

• Authors : da Silva YK; LaFI-Laboratório de Farmacologia e Imunidade, Instituto de Ciências Biológicas e da Saúde, Universidade Federal de Alagoas, Maceió 57072-900, AL, Brazil. .; Reyes CT

Subjects: Analgesics/Analgesics/Analgesics/*chemistry ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*chemistry ; Hydrazones/Hydrazones/Hydrazones/*chemistry

• Source: Molecules (Basel, Switzerland) [Molecules] 2014 Jun 20; Vol. 19 (6), pp. 8456-71. Date of Electronic Publication: 2014 Jun 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Design, synthesis, antinociceptive and anti-inflammatory activities of novel piroxicam analogues.

• Authors : de Miranda AS; Bio - Laboratório de Avaliação e Síntese de Substâncias Bioativas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, P.O. Box 68024, 21944-971 Rio de Janeiro, RJ, Brazil.; Bispo Júnior W

Subjects: Analgesics*/Analgesics*/Analgesics*/chemical synthesis ; Analgesics*/Analgesics*/Analgesics*/pharmacology ; Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/chemical synthesis

• Source: Molecules (Basel, Switzerland) [Molecules] 2012 Nov 28; Vol. 17 (12), pp. 14126-45. Date of Electronic Publication: 2012 Nov 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Novel Regioisomeric Analogues of Naphthyl- N -Acylhydrazone Derivatives and Their Anti-Inflammatory Effects.

• Authors : da Costa Salomé, Dayana¹ (AUTHOR); de Freitas, Rosana Helena Coimbra Nogueira² (AUTHOR); Fraga, Carlos Alberto Manssour² (AUTHOR)

Subjects: *NITRIC-oxide synthases; *DRUG development; *CELL migration

• Source: International Journal of Molecular Sciences. Nov2022, Vol. 23 Issue 21, p13562. 20p.

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LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.

• Authors : Silva, Juliane Cabral¹; Oliveira Júnior, Raimundo Gonçalves de¹; Silva, Mariana Gama e¹

Subjects: *HYDRAZONE derivatives; *INFLAMMATION treatment; *NOCICEPTIVE pain

• Source: PLoS ONE. 7/30/2018, Vol. 13 Issue 7, p1-19. 19p.

تفاصيل العنوان

Novel Orally Active Analgesic and Anti-Inflammatory Cyclohexyl-N-Acylhydrazone Derivatives.

• Authors : Fernandes da Silva, Tiago^1,2 ; Bispo Júnior, Walfrido³ ; Alexandre-Moreira, Magna Suzana³

Subjects: *ANALGESICS; *ANTI-inflammatory agents; *CHEMICAL derivatives

• Source: Molecules. Feb2015, Vol. 20 Issue 2, p3067-3088. 22p. 4 Diagrams, 1 Chart, 3 Graphs.

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Novel Potent Imidazo[1,2-a]pyridine-N-Glycinyl-Hydrazone Inhibitors of TNF-α Production: In Vitro and In Vivo Studies.

• Authors : Lacerda, Renata B.^1,2; Sales, Natália M.^3,4; da Silva, Leandro L.^3,5

Subjects: *HYDRAZONES; *TUMOR necrosis factors; *IN vitro studies

• Source: PLoS ONE. Mar2014, Vol. 9 Issue 3, p1-10. 10p.

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