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  • 1-10 ل  53,885 نتائج ل ""AMYOTROPHIC lateral sclerosis""
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Academic Journal

Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington's disease.

  • Authors : Ou K; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Key Laboratory of Non-Human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, 510632, China.; Jia Q

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/drug therapy ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/therapy

  • Source: Translational neurodegeneration [Transl Neurodegener] 2025 Jan 21; Vol. 14 (1), pp. 4. Date of Electronic Publication: 2025 Jan 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158

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Academic Journal

Evaluation of a biomarker for amyotrophic lateral sclerosis derived from a hypomethylated DNA signature of human motor neurons.

  • Authors : Harvey C; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.; Nowak A

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/blood ; Motor Neurons*/Motor Neurons*/Motor Neurons*/metabolism

  • Source: BMC medical genomics [BMC Med Genomics] 2025 Jan 14; Vol. 18 (1), pp. 10. Date of Electronic Publication: 2025 Jan 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium: Internet ISSN: 1755-8794

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Academic Journal

Genetic epidemiology of amyotrophic lateral sclerosis in Cyprus: a population-based study.

  • Authors : Mitsi E; Neurogenetics Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.; Neuroepidemiology Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/epidemiology ; C9orf72 Protein*/C9orf72 Protein*/C9orf72 Protein*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Dec 28; Vol. 14 (1), pp. 30781. Date of Electronic Publication: 2024 Dec 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Th17 and effector CD8 T cells relate to disease progression in amyotrophic lateral sclerosis: a case control study.

  • Authors : Itou T; Oncology Drug Discovery Unit Japan, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.; Fujita K

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/immunology ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/pathology ; Disease Progression*

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Dec 27; Vol. 21 (1), pp. 331. Date of Electronic Publication: 2024 Dec 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

Artificial Intelligence-Assisted Comparative Analysis of the Overlapping Molecular Pathophysiology of Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.

  • Authors : Wei Z; Laboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30322, USA.; Iyer MR

Subjects: Frontotemporal Dementia*/Frontotemporal Dementia*/Frontotemporal Dementia*/genetics ; Frontotemporal Dementia*/Frontotemporal Dementia*/Frontotemporal Dementia*/metabolism ; Frontotemporal Dementia*/Frontotemporal Dementia*/Frontotemporal Dementia*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 15; Vol. 25 (24). Date of Electronic Publication: 2024 Dec 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis.

  • Authors : Ko VI; Neuroscience Graduate Program, University of California, 9500 Gilman Drive, San Diego, La Jolla, CA, 92093-0624, USA.; Department of Neurosciences, University of California, 9500 Gilman Drive, San Diego, La Jolla, CA, 92093-0624, USA.

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/metabolism ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/pathology ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Dec 04; Vol. 12 (1), pp. 187. Date of Electronic Publication: 2024 Dec 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

Single-cell RNA sequencing highlights the role of distinct natural killer subsets in sporadic amyotrophic lateral sclerosis.

  • Authors : Álvarez-Sánchez E; Memory Unit, Neurology Department and Institut de Recerca Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Sant Quintí 77-79, 08041, Barcelona, Spain.; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain.

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/immunology ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/blood

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2025 Jan 23; Vol. 22 (1), pp. 15. Date of Electronic Publication: 2025 Jan 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

Mendelian randomization study supports relative carbohydrate intake as an independent risk factor for amyotrophic lateral sclerosis.

  • Authors : Zeng Y; Department of Anesthesiology, Third Xiangya Hospital, Central South University, Changsha, People's Republic of China.; Guo R

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Mendelian Randomization Analysis* ; Dietary Carbohydrates*/Dietary Carbohydrates*/Dietary Carbohydrates*/administration & dosage

  • Source: Nutritional neuroscience [Nutr Neurosci] 2025 Jan; Vol. 28 (1), pp. 116-124. Date of Electronic Publication: 2024 May 23.Publisher: Taylor & Francis Country of Publication: England NLM ID: 100892202 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis.

  • Authors : Garcia-Toscano L; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America.; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington, United States of America.

Subjects: Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/genetics ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/metabolism ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics

  • Source: PLoS genetics [PLoS Genet] 2024 Dec 26; Vol. 20 (12), pp. e1011518. Date of Electronic Publication: 2024 Dec 26 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Evaluation of smartphone-based cough data in amyotrophic lateral sclerosis as a potential predictor of functional disability.

  • Authors : Rocha PS; Institute of Physiology, Lisbon School of Medicine, University of Lisbon, Lisbon, Portugal.; Mamede de Carvalho Lab, Institute of Molecular Medicine - João Lobo Antunes, University of Lisbon, Lisbon, Portugal.

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/physiopathology ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/complications ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/diagnosis

  • Source: PloS one [PLoS One] 2024 Dec 16; Vol. 19 (12), pp. e0301734. Date of Electronic Publication: 2024 Dec 16 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 ل  53,885 نتائج ل ""AMYOTROPHIC lateral sclerosis""