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Subject : administration, oral

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Evobrutinib, a covalent Bruton’s tyrosine kinase inhibitor: Mass balance, elimination route, and metabolism in healthy participants

Authors : Eleanor Harrison-Moench; Jan J. van Lier; Jennifer Dong

Subjects: Adult; Male; Drug

Source: Clinical and Translational Science, Vol 14, Iss 6, Pp 2420-2430 (2021)Clinical and Translational Science

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Pharmacokinetic and Adsorptive Analyses of Administration of Oral Voriconazole Suspension via Enteral Feeding Tube in Intensive Care Unit Patients

Authors : Norihisa Yasuda; Yoshifumi Ohchi; Koji Goto

Subjects: Male; 0301 basic medicine; Antifungal Agents

Source: Biological and Pharmaceutical Bulletin. 44:737-741

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Prediction of Oral Pharmacokinetics Using a Combination of In Silico Descriptors and In Vitro ADME Properties

Authors : Yohei Kosugi; Natalie Hosea

Subjects: Male; Correlation coefficient; Metabolic Clearance Rate

Source: Molecular Pharmaceutics. 18:1071-1079

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Population-based meta-analysis of chloroquine: informing chloroquine pharmacokinetics in COVID-19 patients

Authors : Ting Cai; Jing Lin; Xiaoyu Yan

Subjects: Adult; Male; Coronavirus disease 2019 (COVID-19)

Source: European Journal of Clinical Pharmacology

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Mass balance, pharmacokinetics and pharmacodynamics of intravenous HSK3486, a novel anaesthetic, administered to healthy subjects

Authors : Liyan Miao; Sheng Ma; Shiping Ma

Subjects: Metabolic Clearance Rate; Sedation; Metabolite

Source: British Journal of Clinical Pharmacology. 87:93-105

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Remimazolam Has Low Oral Bioavailability and No Potential for Misuse in Drug-Facilitated Sexual Assaults, with or Without Alcohol: Results from Two Randomised Clinical Trials

Authors : Lynn R. Webster; Thomas Stohr; Martin Donsbach

Subjects: Adult; Metabolic Clearance Rate; medicine.drug_class

Source: Drugs in R&D, Vol 20, Iss 3, Pp 267-277 (2020)Drugs in R&D

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A phase I study investigation of metabolism, and disposition of [14C]-anlotinib after an oral administration in patients with advanced refractory solid tumors

Authors : Lian Guo; Yiqian Liu; Lianke Liu

Subjects: 0301 basic medicine; Male; Cancer Research

Source: Cancer Chemotherapy and Pharmacology

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Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine

Authors : Stephanie L Gibson; Gordon L Carlson; P. Davies

Subjects: Drug; Adult; Male

Source: Drug Metabolism and DispositionDrug Metab Dispos

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Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats

Authors : Taiji Miyake

Subjects: Cyclopropanes; Male; 0301 basic medicine

Source: Biological and Pharmaceutical Bulletin. 43:384-392

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Use of amlodipine oral solution for the treatment of hypertension in children

Authors : Roos W.G. van Rooij-Kouwenhoven; Karlien Cransberg; Lidwien M. Hanff ...

Subjects: Male; medicine.medical_specialty; Dose

Source: International Journal of Clinical Pharmacy, 42, 848-852International Journal of Clinical Pharmacy, 42, 3, pp. 848-852International Journal of Clinical Pharmacy, 42(3), 848-852. Springer

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