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Mesenchymal stem cells protect the integrity of the alveolar epithelial barrier through extracellular vesicles by inhibiting MAPK-mediated necroptosis.

• Authors : Ruan T; Stem Cell and Biotherapy Engineering Research Center of Henan, College of Life Science and Technology, Xinxiang Medical University, Xinxiang, 453003, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, School of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, China.

Subjects: Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/transplantation ; Necroptosis*

• Source: Stem cell research & therapy [Stem Cell Res Ther] 2025 May 19; Vol. 16 (1), pp. 250. Date of Electronic Publication: 2025 May 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512

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Fludarabine attenuates inflammation and dysregulated autophagy in alveolar macrophages via inhibition of STAT1/IRF1 pathway.

• Authors : Lee, Jooyeon¹ (AUTHOR); Park, Jeong-Ran¹ (AUTHOR); Lee, Hanbyeol¹ (AUTHOR)

• Source: Laboratory Animal Research. 5/7/2025, Vol. 41 Issue 1, p1-14. 14p.

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Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway

• Authors : Xin Zhou; Zhibin Wang; Yuting Wang

Subjects: acute lung injury; cGAS-STING pathway; NLRP3 inflammasome

• Source: Frontiers in Pharmacology, Vol 16 (2025)

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Oxidative damage to lung mitochondrial DNA is a key contributor to the development of chemical lung injury

• Authors : Shubham Dubey; Zhihong Yu; Emily Morgan Stephens

Subjects: Chlorine; 8-Oxoguanine DNA glycosylase (OGG1); Acute lung injury

• Source: Redox Biology, Vol 82, Iss , Pp 103624- (2025)

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An Observational Study to Identify New Health Problems Arising After an Intensive Care Unit Admission in People With Acute Respiratory Distress Syndrome in the United States (SeeMe Tool)

• Source: Identifying Post ICU Morbidity in Patients With ARDS in the United States

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Treatment of ARDS With Sivelestat Sodium (TOAWSS)

• Authors : He Hongli, Principal Investigator

• Source: Efficacy of Sivelestat Sodium in the Treatment of ARDS With SIRS, a Multicenter Double-blind Randomized Controlled Clinical Trial

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Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome (LEOPARDS)

• Authors : Akron Children's Hospital; Children's Hospital and Health System Foundation, Wisconsin; Children's Hospital Medical Center, Cincinnati

• Source: Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

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Mechanical Power Normalized to Compliance in ARDS

• Authors : Roberto Santa Cruz, Principal Investigator

• Source: Mechanical Power Normalized to Compliance in Patients With Acute Respiratory Distress Syndrome

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Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome (ARDS-MSC-205)

• Authors : Uppsala University Hospital

• Source: Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome Validation of

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EIT-Guided Ventilator Settings in AHRF

• Source: Using Electrical Impedance Tomography-Guided Ventilator Settings to Reduce Mechanical Power in Acute Hypoxemic Respiratory Failure : An Exploratory Study

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