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Targeting autophagy using small-molecule compounds to improve potential therapy of Parkinson's disease

• Authors : Lu Feng; Kai Zhang; Bo Liu

Subjects: Target; ONRs, orphan nuclear receptors; Parkinson's disease

• Source: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)Acta Pharmaceutica Sinica. B

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Critical roles of parkin and PINK1 in coxsackievirus B3-induced viral myocarditis

• Authors : Jin, U; Park, SJ; Lee, BG ...

Subjects: Animals; Coxsackievirus Infections; Disease Models

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Augmenter of liver regeneration-mediated mitophagy protects against hepatic ischemia/reperfusion injury

• Authors : Chun Bai; Wen Li; Yuan Wu

Subjects: MFN2; Apoptosis; PINK1

• Source: American Journal of Transplantation. 22:130-143

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DJ-1 Deficiency in Hepatocytes Improves Liver Ischemia-Reperfusion Injury by Enhancing Mitophagy

• Authors : Min Xu; Fang Wang; Xiaoni Kong

Subjects: 0301 basic medicine; Male; DJ-1

• Source: Cellular and Molecular Gastroenterology and HepatologyCellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 567-584 (2021)

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Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy

• Authors : Peng Hong; Jun Xu; Qilei Chen

Subjects: 0303 health sciences; Programmed cell death; Chemistry

• Source: Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3966-3982 (2021)Acta Pharmaceutica Sinica. B

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MiR-144-3p induced by SP1 promotes IL-1β-induced pyroptosis in chondrocytes via PTEN/PINK1/Parkin axis

• Authors : Jin-Mei Jiang; Mei-Li Mo; Li-Hu Xie

Subjects: Sp1 transcription factor; Gene knockdown; biology

• Source: Autoimmunity. 55:21-31

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Ablation of Akt2 and AMPKα2 rescues high fat diet-induced obesity and hepatic steatosis through Parkin-mediated mitophagy

• Authors : Mingming Sun; Gary D. Lopaschuk; Huaguo Chen

Subjects: AMPK; High fat intake; medicine.medical_specialty

• Source: Acta Pharmaceutica Sinica. BActa Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3508-3526 (2021)

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Human antigen R regulates hypoxia‐induced mitophagy in renal tubular cells through PARKIN/BNIP3L expressions

• Authors : Kuo-Ting Sun; Feng-Yen Lin; Kuen-Bao Chen

Subjects: 0301 basic medicine; Ubiquitin-Protein Ligases; Gene Expression

• Source: Journal of Cellular and Molecular Medicine

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Dysregulation of mitochondrial dynamics, mitophagy and apoptosis in major depressive disorder: Does inflammation play a role?

• Authors : Alexandre Paim Diaz; João Quevedo; Jair C. Soares

Subjects: medicine.medical_specialty; business.industry; Inflammation

• Source: Molecular Psychiatry. 27:1095-1102

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Pathways to Parkinson’s disease: a spotlight on 14-3-3 proteins

• Authors : Elisa Greggio; Talene A. Yacoubian; L. Civiero

Subjects: Parkinson's disease; Drug discovery; Diseases

• Source: npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-14 (2021)NPJ Parkinson's Disease

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