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Subject : 030104 developmental biology

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Allosteric HIV-1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter-subunit interactions: Structural and thermodynamic modeling studies

Authors : Nanjie Deng; Ashley C. Hoyte; Alan Engelman

Subjects: 0301 basic medicine; 030102 biochemistry & molecular biology; biology

Source: Protein Science. 25:1911-1917

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Identification of N-glycans with GalNAc-containing antennae from recombinant HIV trimers by ion mobility and negative ion fragmentation

Authors : David Harvey; Anna-Janina Behrens; Max Crispin

Subjects: 0301 basic medicine; Spectrometry, Mass, Electrospray Ionization; Glycan

Source: Analytical and Bioanalytical Chemistry

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Early origin of sweet perception in the songbird radiation

Authors : Maude W. Baldwin; Takashi Hayakawa; Alejandro Rico-Guevara

Subjects: 0106 biological sciences; 0301 basic medicine; Sucrose

Source: Science. 373:226-231

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Hetero-oligomerization of Bacillus thuringiensis Cry1A proteins enhance binding to the ABCC2 transporter of Spodoptera exigua

Authors : Noelia Joya; Daniel Pinos; Juan Ferré

Subjects: 0301 basic medicine; Cell Survival; Bacillus thuringiensis

Source: Biochemical Journal. 478:2589-2600

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Heterodimer Formation of the Homodimeric ABC Transporter OpuA

Authors : Bert Poolman; Hendrik R Sikkema; Patricia Alvarez-Sieiro ...

Subjects: 0301 basic medicine; OpuA; nanodisc reconstitution

Source: International Journal of Molecular SciencesVolume 22Issue 11International Journal of Molecular Sciences, 22(11):5912. MDPI AGInternational Journal of Molecular Sciences, Vol

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The umami receptor T1R1–T1R3 heterodimer is rarely formed in chickens

Authors : Fuminori Kawabata; Shoji Tabata; Shotaro Nishimura

Subjects: 0301 basic medicine; Taste; Science

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)Scientific Reports

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Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization

Authors : Martin Schwill; Jakob C. Stüber; Christian Richter ...

Subjects: 0301 basic medicine; Receptor, ErbB-2; QH301-705.5

Source: Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)Communications Biology

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The G127V variant of the prion protein interferes with dimer formation in vitro but not in cellulo

Authors : Sudheer Babu Sangeetham; Sarah Laura Krausz; Jörg Tatzelt

Subjects: 0301 basic medicine; Gene isoform; Prion diseases

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)Scientific Reports

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Structural characterization of a GNAT family acetyltransferase from Elizabethkingia anophelis bound to acetyl-CoA reveals a new dimeric interface

Authors : P. Shirmast; Stephen J. Mayclin; Jan Abendroth

Subjects: Models, Molecular; 0301 basic medicine; Protein Conformation

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)Scientific Reports

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Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha

Authors : Mary C. Beckerle; Masaaki Yoshigi; Julie L. Kadrmas

Subjects: 0301 basic medicine; Cell biology; Receptor, Platelet-Derived Growth Factor alpha

Source: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)Scientific Reports

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