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Subject : 030104 developmental biology

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Ex vivo model predicted in vivo efficacy of CFTR modulator therapy in a child with rare genotype

Authors : Vito Terlizzi; Giuseppe Castaldo; Felice Amato ...

Subjects: 0301 basic medicine; Oncology; Aminopyridines

Source: Molecular Genetics & Genomic Medicine, Vol 9, Iss 4, Pp n/a-n/a (2021)Molecular Genetics & Genomic Medicine

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A Systematic Review of the Clinical Efficacy and Safety of CFTR Modulators in Cystic Fibrosis

Authors : Bradley S. Quon; Sameer Desai; Majid Kajbafzadeh

Subjects: 0301 basic medicine; medicine.medical_specialty; Indoles

Source: Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)Scientific Reports

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Agonist and antagonist properties of an insect GABA-gated chloride channel (RDL) are influenced by heterologous expression conditions

Authors : Charles L.C. Smelt; Jim Goodchild; Victoria R. Sanders

Subjects: 0301 basic medicine; Nicotinic Acetylcholine Receptors; Molecular biology

Source: PLoS ONE, Vol 16, Iss 7, p e0254251 (2021)PLoS ONE

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Cobalt ion interaction with TMEM16A calcium-activated chloride channel: Inhibition and potentiation

Authors : Grace Jeng; Louisa S. Chen; Wei Ping Yu ...

Subjects: 0301 basic medicine; Phospholipid scramblase; Fungal Structure

Source: PLoS ONE, Vol 15, Iss 4, p e0231812 (2020)PLoS ONEPloS one, vol 15, iss 4

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Investigation of the effects of the CFTR potentiator ivacaftor on human P-glycoprotein (ABCB1)

Authors : Robert C. Ford; Nopnithi Thonghin; Swathi Lingam

Subjects: 0301 basic medicine; ATP Binding Cassette Transporter, Subfamily B; lcsh:Medicine

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)Lingam, S, Thonghin, N & Ford, R C 2017, ' Investigation of the effects of the CFTR potentiator ivacaftor on human P-glycoprotein (ABCB1) ',

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Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice

Authors : Shintaro Minegishi; Kouichi Tamura; Sae Saigoh-Teranaka

Subjects: 0301 basic medicine; Apolipoprotein E; Apolipoprotein B

Source: PLoS ONE, Vol 14, Iss 6, p e0218096 (2019)PLoS ONE

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Short Chain Fatty Acids Effect on Chloride Channel ClC-2 as a Possible Mechanism for Lubiprostone Intestinal Action

Authors : Francisco V. Sepúlveda; Luis Pablo Cid; Francisca Julio-Kalajzić

Subjects: 0301 basic medicine; ClC-2; lubiprostone

Source: CellsCells, Vol 9, Iss 1781, p 1781 (2020)Volume 9Issue 8

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Lubiprostone improves intestinal permeability in humans, a novel therapy for the leaky gut: A prospective randomized pilot study in healthy volunteers

Authors : Yuji Ogawa; Koichiro Wada; Atsushi Nakajima

Subjects: Male; 0301 basic medicine; Physiology

Source: PLoS ONE, Vol 12, Iss 4, p e0175626 (2017)PLoS ONE

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