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Academic Journal

Gefitinib metabolism-related lncRNAs for the prediction of prognosis, tumor microenvironment and drug sensitivity in lung adenocarcinoma.

  • Authors : Guo Z; Department of Thoracic Surgery, The Second Affiliated Hospital, Jiangxi Medical College , Nanchang University, 1 Minde Road, Nanchang, 330006, China.; Zhang X

Subjects: Tumor Microenvironment*/Tumor Microenvironment*/Tumor Microenvironment*/genetics ; Tumor Microenvironment*/Tumor Microenvironment*/Tumor Microenvironment*/immunology ; Gefitinib*/Gefitinib*/Gefitinib*/therapeutic use

  • Source: Scientific reports [Sci Rep] 2024 May 06; Vol. 14 (1), pp. 10348. Date of Electronic Publication: 2024 May 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

ELK1/MTOR/S6K1 Pathway Contributes to Acquired Resistance to Gefitinib in Non-Small Cell Lung Cancer.

  • Authors : Zhao L; Department of Pathology and Genomic Medicine, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.; Wang Y

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 17; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Circ_0001786 facilitates gefitinib resistance and malignant progression in non-small cell lung cancer via miR-34b-5p/SRSF1.

  • Authors : Ouyang K; Department of Medical Oncology, Huizhou Municipal Central Hospital of Guangdong Province, NO.41 North Eling Road, Huizhou, 516000, Guangdong Province, China.; Xie D

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy

  • Source: Journal of cardiothoracic surgery [J Cardiothorac Surg] 2024 Apr 05; Vol. 19 (1), pp. 178. Date of Electronic Publication: 2024 Apr 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101265113 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-8090

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Academic Journal

Leucine Zipper Downregulated in Cancer-1 Interacts with Clathrin Adaptors to Control Epidermal Growth Factor Receptor (EGFR) Internalization and Gefitinib Response in EGFR-Mutated Non-Small Cell Lung Cancer.

  • Authors : Huang HN; Department of Pathology, National Taiwan University Hospital Hsin-Chu Branch, No. 25, Ln. 442, Section 1, Jingguo Road, North Dist., Hsinchu 300195, Taiwan.; Department and Graduate Institute of Pathology, College of Medicine, National Taiwan University, No. 1 Jen Ai Road Section 1, Taipei 100225, Taiwan.

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 23; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

On chip synthesis of a pH sensitive gefitinib anticancer drug nanocarrier based on chitosan/alginate natural polymers.

  • Authors : Alizadeh H; Faculty of Chemistry and Petroleum Sciences, Bu-Ali Sina University, Hamedan, Iran.; Ahmadi M

Subjects: Chitosan* ; Carcinoma, Non-Small-Cell Lung* ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy

  • Source: Scientific reports [Sci Rep] 2024 Jan 08; Vol. 14 (1), pp. 772. Date of Electronic Publication: 2024 Jan 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lazertinib versus Gefitinib as First-Line Treatment for EGFR-mutated Locally Advanced or Metastatic NSCLC: LASER301 Korean Subset.

  • Authors : Lee KH; Division of Medical Oncology, Department of Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.; Cho BC

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy

  • Source: Cancer research and treatment [Cancer Res Treat] 2024 Jan; Vol. 56 (1), pp. 48-60. Date of Electronic Publication: 2023 Jun 27.Publisher: The Association Country of Publication: Korea (South) NLM ID: 101155137 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovery of gefitinib-1,2,3-triazole derivatives against lung cancer via inducing apoptosis and inhibiting the colony formation.

  • Authors : Gao E; School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, 453000, China. .; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, China. .

Subjects: Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/pathology ; Gefitinib*/Gefitinib*/Gefitinib*/pharmacology

  • Source: Scientific reports [Sci Rep] 2024 Apr 22; Vol. 14 (1), pp. 9223. Date of Electronic Publication: 2024 Apr 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Impact of Inadequate Exposure to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors on the Development of Resistance in Non-Small-Cell Lung Cancer Cells.

  • Authors : Frezzetti D; Cell Biology and Biotherapy Unit, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Naples, Italy.; Caridi V

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 29; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

[Effect of SLC7A11 gene downregulation on the gefitinib resistance of lung adenocarcinoma PC9/GR cells and its mechanism].

  • Authors : Jia YL; Department of Tumor Immunotherapy, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.; Zhao Y

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/pathology

  • Source: Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2023 Sep 23; Vol. 45 (9), pp. 779-786.Publisher: Chinese Medical Association Country of Publication: China NLM ID: 7910681 Publication Model: Print Cited Medium: Print ISSN: 0253-3766

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Academic Journal

BYL719 reverses gefitinib-resistance induced by PI3K/AKT activation in non-small cell lung cancer cells.

  • Authors : Yu Y; The Second Clinical Medical School of Guangzhou University of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.; Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism

  • Source: BMC cancer [BMC Cancer] 2023 Aug 08; Vol. 23 (1), pp. 732. Date of Electronic Publication: 2023 Aug 08.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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