نتائج البحث

Recent discoveries in HIV-1 reverse transcriptase inhibitors

• Authors : Lu Huang; Yuan-Yuan Zhu; Shuang Cao

Subjects: 0301 basic medicine; Drug; 2019-20 coronavirus outbreak

• Source: Current Opinion in Pharmacology

تفاصيل العنوان

High levels of resistance to nucleoside/nucleotide reverse transcriptase inhibitors in newly diagnosed antiretroviral treatment-naive children in sub-Saharan Africa

• Authors : Innocent A Mbulli; Sulaimon Akanmu; Martina Penazzato ...

Subjects: 0301 basic medicine; Anti-HIV Agents; Immunology

• Source: AIDS (London, England), 34(10), 1567-1570. Lippincott Williams and Wilkins

تفاصيل العنوان

Chronic Nucleoside Reverse Transcriptase Inhibitors Disrupt Mitochondrial Homeostasis and Promote Premature Endothelial Senescence

• Authors : Brian A. Irving; James E. Stampley; Yi-Fan Chen

Subjects: 0301 basic medicine; Endothelium; Anti-HIV Agents

• Source: Toxicological Sciences. 172:445-456

تفاصيل العنوان

Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV‐1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine

• Authors : Nicole Bertoletti; Karen S. Anderson; Albert H. Chan

Subjects: Models, Molecular; Protein Conformation; Full‐Length Papers

• Source: Protein Sci

تفاصيل العنوان

Associations between plasma nucleoside reverse transcriptase inhibitors concentrations and cognitive function in people with HIV

• Authors : Saye Khoo; Daphne Babalis; Jonathan Underwood

Subjects: Oncology; Central Nervous System; RNA viruses

• Source: PLoS ONEPLoS ONE, Vol 16, Iss 7, p e0253861 (2021)

تفاصيل العنوان

Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration

• Authors : Bradley D. Gelfand; Yosuke Nagasaka; Peirong Huang

Subjects: Male; 0301 basic medicine; Cancer Research

• Source: Signal Transduction and Targeted TherapySignal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-9 (2021)

تفاصيل العنوان

Treatment outcomes of integrase inhibitors, boosted protease inhibitors and nonnucleoside reverse transcriptase inhibitors in antiretroviral-naïve persons starting treatment

• Authors : J Tiraboschi; B Neesgard; Nikoloz Chkhartishvili ...

Subjects: 0301 basic medicine; Adult; Male

• Source: HIV medicine, 21(9), 599-606. Wiley-BlackwellMocroft, A (2020). Treatment outcomes of integrase inhibitors, boosted protease

تفاصيل العنوان

Molecular Hybridization-Inspired Optimization of Diarylbenzopyrimidines as HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors with Improved Activity against K103N and E138K Mutants and Pharmacokinetic Profiles

• Authors : Yali Sang; Sheng Han; Yuan Tao

Subjects: 0301 basic medicine; NNRTI; STRUCTURAL BASIS

تفاصيل العنوان

The Journey of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) from Lab to Clinic

• Authors : Peng Zhan; Sonali Kurup; Jacob Kongsted

Subjects: Efavirenz; Nevirapine; Anti-HIV Agents

• Source: Namasivayam, V, Vanangamudi, M, Kramer, V G, Kurup, S, Zhan, P, Liu, X, Kongsted, J & Byrareddy, S N 2019, ' The Journey of HIV-1 Non-Nucleoside Reverse

تفاصيل العنوان

Impact of transmitted HIV-1 drug resistance on the efficacy of first-line antiretroviral therapy with two nucleos(t)ide reverse transcriptase inhibitors plus an integrase inhibitor or a protease inhibitor

• Authors : Giacomo Zanelli; A. Antinori; Manuela Colafigli

Subjects: Adult; Male; 0301 basic medicine

• Source: Journal of Antimicrobial Chemotherapy. 73:2480-2484

تفاصيل العنوان