Source: Kitchen, G B, Cunningham, P S, Poolman, T M, Iqbal, M, Maidstone, R, Baxter, M, Bagnall, J, Begley, N, Saer, B, Hussell, T, Matthews, L C, Dockrell, D H, Durrington, H J, Gibbs, J E, Blaikley, J F,

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Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells

Authors : Galmarini, Carlos M; Martin, Maud; Bouchet, Benjamin Pierre ...

Subjects: Physiologic/drug effects; 0301 basic medicine; Cancer Research

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)BMC CancerBMC Cancer, 18(1). BioMed CentralBMC cancer, 18 (1

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EBI2 Expression and Function: Robust in Memory Lymphocytes and Increased by Natalizumab in Multiple Sclerosis

Authors : Amandine Mathias; Andreas W. Sailer; Renaud Du Pasquier

Subjects: Adult; CD4-Positive T-Lymphocytes; 0301 basic medicine

Source: Cell Reports, Vol. 18, No 1 (2017) pp. 213-224Cell reports, vol. 18, no. 1, pp. 213-224

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The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion

Authors : Raphael Gaudin; Denise J. Roe; Ghassan Mouneimne ...

Subjects: 0301 basic medicine; Transcription, Genetic; [SDV]Life Sciences [q-bio]

Source: Nature CommunicationsNature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-05367-2⟩Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)Nature

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Cytotoxic anti-circumsporozoite antibodies target malaria sporozoites in the host skin

Authors : Silvia Beatriz Boscardin; Tomoko Ishino; Marcio Massao Yamamoto ...

Subjects: 0301 basic medicine; MESH: Antibodies, Protozoan/pharmacology; Plasmodium berghei

Source: Nature MicrobiologyNature Microbiology, 2018, 3 (11), pp.1224-1233. ⟨10.1038/s41564-018-0254-z⟩Nature Microbiology, Nature Publishing Group, 2018, 3 (11), pp.1224-1233.

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αVβ3 Integrin regulates astrocyte reactivity

Authors : Milene Kong; Edgardo Rojas-Mancilla; Alvaro Alvarez

Subjects: 0301 basic medicine; Integrins; Cell signaling

Source: Journal of neuroinflammation, vol. 14, no. 1, pp. 194Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-13 (2017)

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Combination of ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity

Authors : Patrycja Nowak-Sliwinska; Tse J. Wong; U. Kulsoom Abdul

Subjects: 0301 basic medicine; Physiologic/drug effects; Nude

Source: Scientific Reports, Vol. 7 (2017) P. 43005Scientific Reports

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CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma

Authors : Johannes Neu; Piotr Dziunycz; Karine Lefort ...

Subjects: 0301 basic medicine; Keratinocytes; Skin Neoplasms

Source: PLoS ONE, Vol 12, Iss 4, p e0173000 (2017)PLoS One, vol. 12, no. 4, pp. e0173000PLoS ONE

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A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

Authors : Riccardo Ferro; Andrew M. Riley; Marco Falasca

Subjects: 0301 basic medicine; Inositol Phosphates/pharmacology; Cell Movement/drug effects

Source: Scientific ReportsRaimondi, C, Calleja, V, Ferro, R, Fantin, A, Riley, A M, Potter, B V L, Brennan, C H, Maffucci, T, Larijani, B & Falasca, M 2016, ' A Small Molecule Inhibitor of PDK1/PLCγ1

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Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy

Authors : Rosa Barreira da Silva; Melissa E Laird; Nader Yatim ...

Subjects: Male; Adoptive cell transfer; Lymphocyte

Source: Nature ImmunologyNature Immunology, 2015, 16 (8), pp.850-858. ⟨10.1038/ni.3201⟩Nature Immunology, Nature Publishing Group, 2015, 16 (8), pp.850-858. ⟨10.1038/ni.3201⟩

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