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  • 1-10 ل  3,357 نتائج ل ""Hypoxia-Inducible Factor 1, alpha Subunit""
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Academic Journal

HIF-1α-HPRT1 axis promotes tumorigenesis and gefitinib resistance by enhancing purine metabolism in EGFR-mutant lung adenocarcinoma.

  • Authors : Geng P; State Key Laboratory of Medical Proteomics, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning Province, 116023, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian, Liaoning Province, 116023, China.

Subjects: ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/metabolism ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/genetics ; Gefitinib*/Gefitinib*/Gefitinib*/pharmacology

  • Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Sep 30; Vol. 43 (1), pp. 269. Date of Electronic Publication: Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Academic Journal

Histone variant H2AZ1 drives lung cancer progression through the RELA-HIF1A-EGFR signaling pathway.

  • Authors : Zhao H; Department of Human Cell Biology and Genetics, Joint Laboratory of Guangdong-Hong Kong Universities for Vascular Homeostasis and Diseases, School of Medicine, Southern University of Science and Technology, No. 1088, Xueyuan Road, Nanshan District, Shenzhen, Guangdong Province, 518055, China.; Department of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Subjects: Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/pathology ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/genetics ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/metabolism

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 26; Vol. 22 (1), pp. 453. Date of Electronic Publication: 2024 Sep 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

TRPA1 Influences Staphylococcus aureus Skin Infection in Mice and Associates with HIF-1a and MAPK Pathway Modulation.

  • Authors : Yadav M; Epithelial Therapeutic Unit, National Institute of Allergy, and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA.; Chaudhary PP

Subjects: TRPA1 Cation Channel*/TRPA1 Cation Channel*/TRPA1 Cation Channel*/metabolism ; TRPA1 Cation Channel*/TRPA1 Cation Channel*/TRPA1 Cation Channel*/genetics ; Methicillin-Resistant Staphylococcus aureus*/Methicillin-Resistant Staphylococcus aureus*/Methicillin-Resistant Staphylococcus aureus*/drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 14; Vol. 25 (18). Date of Electronic Publication: 2024 Sep 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Evaluation of SBDP145, melatonin, sLOX-1, HMGB1 and HIF-1α in preterm infants with brain injury.

  • Authors : Cheng S; Department of Pediatrics, The First Hospital of Hebei Medical University, No. 89 Donggang Road, Yuhua District, Shijiazhuang, Hebei, 050000, China.; Sun X

Subjects: HMGB1 Protein*/HMGB1 Protein*/HMGB1 Protein*/blood ; Melatonin*/Melatonin*/Melatonin*/blood ; Infant, Premature*

  • Source: Italian journal of pediatrics [Ital J Pediatr] 2024 Sep 11; Vol. 50 (1), pp. 172. Date of Electronic Publication: 2024 Sep 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101510759 Publication Model: Electronic Cited Medium: Internet ISSN: 1824-7288

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Academic Journal

PHD2 safeguards modest mesendoderm development.

  • Authors : Li M; College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China.; Jin H

Subjects: Hypoxia-Inducible Factor-Proline Dioxygenases*/Hypoxia-Inducible Factor-Proline Dioxygenases*/Hypoxia-Inducible Factor-Proline Dioxygenases*/metabolism ; Hypoxia-Inducible Factor-Proline Dioxygenases*/Hypoxia-Inducible Factor-Proline Dioxygenases*/Hypoxia-Inducible Factor-Proline Dioxygenases*/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism

  • Source: Communications biology [Commun Biol] 2024 Sep 07; Vol. 7 (1), pp. 1100. Date of Electronic Publication: 2024 Sep 07.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

HOTAIR Promotes the Hyperactivation of PI3K/Akt and Wnt/β-Catenin Signaling Pathways via PTEN Hypermethylation in Cervical Cancer.

  • Authors : Trujano-Camacho S; Experimental Biology PhD Program, DCBS, Universidad Autónoma Metropolitana-Iztapalapa, Mexico City 09340, Mexico.; Laboratorio de Genómica, Instituto Nacional de Cancerología, Av. San Fernando 22, Belisario Domínguez Secc 16, Tlalpan, Ciudad de México 14080, Mexico.

Subjects: Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/genetics ; Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/metabolism ; Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/pathology

  • Source: Cells [Cells] 2024 Sep 04; Vol. 13 (17). Date of Electronic Publication: 2024 Sep 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

DDR1 Drives Malignant Progression of Gastric Cancer by Suppressing HIF-1α Ubiquitination and Degradation.

  • Authors : Wei Z; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, 58 Zhongshan 2nd Road, Guangzhou, Guangdong, 510080, China.; Li J

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/metabolism ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Sep; Vol. 11 (35), pp. e2308395. Date of Electronic Publication: 2024 Jul 18.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Hypoxia Abrogates Tumor-Suppressive Activities of C/EBPδ in Pancreatic Cancer.

  • Authors : Hartl L; Center for Experimental and Molecular Medicine, Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC Location University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 30; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

SPRi Biosensor for Simultaneous Determination of HIF-1α, Angiopoietin-2, and Interleukin-1β in Blood Plasma.

  • Authors : Zielinska Z; Bioanalysis Laboratory, Doctoral School of Exact and Natural Science, Faculty of Chemistry, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, Poland.; Oldak L

Subjects: Interleukin-1beta*/Interleukin-1beta*/Interleukin-1beta*/blood ; Angiopoietin-2*/Angiopoietin-2*/Angiopoietin-2*/blood ; Biosensing Techniques*/Biosensing Techniques*/Biosensing Techniques*/methods

  • Source: Sensors (Basel, Switzerland) [Sensors (Basel)] 2024 Aug 24; Vol. 24 (17). Date of Electronic Publication: 2024 Aug 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101204366 Publication Model: Electronic Cited Medium: Internet ISSN: 1424-8220

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Academic Journal

LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2α accumulation under experimental hypoxia.

  • Authors : Ohgaki R; Department of Bio-System Pharmacology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. .; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Osaka, 565-0871, Japan. .

Subjects: Large Neutral Amino Acid-Transporter 1*/Large Neutral Amino Acid-Transporter 1*/Large Neutral Amino Acid-Transporter 1*/metabolism ; Large Neutral Amino Acid-Transporter 1*/Large Neutral Amino Acid-Transporter 1*/Large Neutral Amino Acid-Transporter 1*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Aug 23; Vol. 14 (1), pp. 19635. Date of Electronic Publication: 2024 Aug 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  3,357 نتائج ل ""Hypoxia-Inducible Factor 1, alpha Subunit""