Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Impaired FADD/BID signaling mediates cross-resistance to immunotherapy in Multiple Myeloma.

  • Authors : Munawar U; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.; Zhou X

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/drug therapy; Humans ; Immunotherapy/Immunotherapy/Immunotherapy/methods

  • Source: Communications biology [Commun Biol] 2023 Dec 21; Vol. 6 (1), pp. 1299. Date of Electronic Publication: 2023 Dec 21.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

×
Academic Journal

High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex.

  • Authors : Zhou X; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.; Besse A

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/pathology; Humans ; Proteasome Endopeptidase Complex

  • Source: Haematologica [Haematologica] 2023 Jun 01; Vol. 108 (6), pp. 1628-1639. Date of Electronic Publication: 2023 Jun 01.Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

×
Academic Journal

Single-Nucleotide Variants and Epimutations Induce Proteasome Inhibitor Resistance in Multiple Myeloma.

  • Authors : Haertle L; Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.; Department of Hematology, Hospital Universitario 12 de Octubre, Spanish National Cancer Research Center, Complutense University Madrid, Madrid, Spain.

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/drug therapy ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/genetics ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/metabolism

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Jan 04; Vol. 29 (1), pp. 279-288.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265

تفاصيل العنوان

×
Academic Journal

CXCR4 expression of multiple myeloma as a dynamic process: influence of therapeutic agents.

  • Authors : Bögelein A; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.; Stolzenburg A

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/drug therapy

  • Source: Leukemia & lymphoma [Leuk Lymphoma] 2022 Oct; Vol. 63 (10), pp. 2393-2402. Date of Electronic Publication: 2022 Jul 08.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

×
Academic Journal

Cereblon enhancer methylation and IMiD resistance in multiple myeloma.

  • Authors : Haertle L; Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.; Institute of Human Genetics, Julius Maximilian University of Würzburg, Würzburg, Germany.

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*genetics ; Antineoplastic Agents, Immunological/Antineoplastic Agents, Immunological/Antineoplastic Agents, Immunological/*therapeutic use ; Immunomodulating Agents/Immunomodulating Agents/Immunomodulating Agents/*therapeutic use

  • Source: Blood [Blood] 2021 Nov 04; Vol. 138 (18), pp. 1721-1726.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020

تفاصيل العنوان

×
Report

IKZF1/3 and CRL4 CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma.

  • Authors : Barrio S; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.; Munawar U

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/drug therapy ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/genetics ; Pharmaceutical Preparations*

  • Source: Haematologica [Haematologica] 2020 May; Vol. 105 (5), pp. e237-e241. Date of Electronic Publication: 2019 Sep 26.Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

×
Academic Journal

CIC Mutation as a Molecular Mechanism of Acquired Resistance to Combined BRAF-MEK Inhibition in Extramedullary Multiple Myeloma with Central Nervous System Involvement.

  • Authors : Da Vià MC; Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.; Solimando AG

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/drug therapy ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/genetics ; Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/genetics

  • Source: The oncologist [Oncologist] 2020 Feb; Vol. 25 (2), pp. 112-118. Date of Electronic Publication: 2019 Oct 18.Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

×
Academic Journal

Assessment of TP53 lesions for p53 system functionality and drug resistance in multiple myeloma using an isogenic cell line model.

  • Authors : Munawar U; Comprehensive Cancer Center Mainfranken, University Hospital of Würzburg, Würzburg, Germany.; Roth M

Subjects: Gene Expression Regulation, Neoplastic*; Antineoplastic Agents, Alkylating/Antineoplastic Agents, Alkylating/Antineoplastic Agents, Alkylating/*pharmacology ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics

  • Source: Scientific reports [Sci Rep] 2019 Dec 02; Vol. 9 (1), pp. 18062. Date of Electronic Publication: 2019 Dec 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

×
Report

Hierarchy of mono- and biallelic TP53 alterations in multiple myeloma cell fitness.

Subjects: Clonal Evolution/Clonal Evolution/Clonal Evolution/*genetics ; Gene Dosage/Gene Dosage/Gene Dosage/*physiology ; Multiple Myeloma/Multiple Myeloma/Multiple Myeloma/*genetics

  • Source: Blood [Blood] 2019 Sep 05; Vol. 134 (10), pp. 836-840. Date of Electronic Publication: 2019 Jul 24.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

×
  • 1-9 of  9 نتائج ل ""Munawar U""