نتائج البحث

Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes.

• Authors : Binder, Moritz; Szalat, Raphael E.; Talluri, Srikanth

Subjects: MESENCHYMAL stem cells; MULTIPLE myeloma; NATURAL history

• Source: Nature Communications; 5/16/2024, Vol. 15 Issue 1, p1-13, 13p

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Pathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma

• Authors : Ruiz Heredia, Yanira; Ortiz Ruiz, Alejandra; Samur, Mehmet K.

Subjects: multiple myeloma; smoldering MM; mitochondria DNA copy number

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Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.

• Authors : Kurata, Keiji; James-Bott, Anna; Tye, Mark A.

Subjects: MULTIPLE myeloma; TRANSCRIPTION factors; PLASMA cells

• Source: Blood Cancer Journal; Jan2023, Vol. 13 Issue 1, p1-12, 12p

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In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors.

• Authors : Aktas Samur, Anil; Fulciniti, Mariateresa; Avet-Loiseau, Herve

Subjects: ALTERNATIVE RNA splicing; MULTIPLE myeloma; WEB portals

• Source: Blood Cancer Journal; Dec2022, Vol. 12 Issue 12, p1-11, 11p

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The shaping and functional consequences of the dosage effect landscape in multiple myeloma

• Authors : Samur, Mehmet K; Shah, Parantu K; Wang, Xujun

Subjects: Copy number alteration; Dosage effect; Multiple myeloma

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Ubiquitin receptor PSMD4/Rpn10 is a novel therapeutic target in multiple myeloma.

• Authors : Du T; Department of Medical Oncology, LeBow Institute for Myeloma Therapeutics and Jerome Lipper Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Harvard University, Boston, MA.; Song Y

Subjects: Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/metabolism ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/drug therapy ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/genetics

• Source: Blood [Blood] 2023 May 25; Vol. 141 (21), pp. 2599-2614.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020

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BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma.

• Authors : Kurata K; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.; Samur MK

Subjects: Transcription Factors*/Transcription Factors*/Transcription Factors*/genetics ; Transcription Factors*/Transcription Factors*/Transcription Factors*/metabolism ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/genetics

• Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 May 01; Vol. 29 (9), pp. 1807-1821.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265

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Dysregulated APOBEC3G causes DNA damage and promotes genomic instability in multiple myeloma.

• Authors : Talluri, Srikanth; Samur, Mehmet K.; Buon, Leutz

Subjects: MULTIPLE myeloma; DNA damage; GENETIC mutation

• Source: Blood Cancer Journal; Oct2021, Vol. 11 Issue 10, p1-11, 11p

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A MIR17HG-derived long noncoding RNA provides an essential chromatin scaffold for protein interaction and myeloma growth.

• Authors : Morelli E; Department of Medical Oncology, Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA.

Subjects: RNA, Long Noncoding*/RNA, Long Noncoding*/RNA, Long Noncoding*/genetics ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism

• Source: Blood [Blood] 2023 Jan 26; Vol. 141 (4), pp. 391-405.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020

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Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma.

• Authors : Richardson PG; DETERMINATION Investigators

Subjects: Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/adverse effects ; Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/therapeutic use ; Maintenance Chemotherapy*/Maintenance Chemotherapy*/Maintenance Chemotherapy*/methods

• Source: The New England journal of medicine [N Engl J Med] 2022 Jul 14; Vol. 387 (2), pp. 132-147. Date of Electronic Publication: 2022 Jun 05.Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium:

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