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  • 1-10 of  16,267 نتائج ل ""Animals""

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Format : Academic Journals Subject : biology and life sciences Subject : multiple myeloma Subject : mutation Subject : terapia celular فلترة بواسطة : موضوع
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Academic Journal

Inhibition of the MDM2 E3 Ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with ABT-737.

  • Authors : Gu D; Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Wang S

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Autophagy/Autophagy/Autophagy/*drug effects ; Biphenyl Compounds/Biphenyl Compounds/Biphenyl Compounds/*pharmacology

  • Source: PloS one [PLoS One] 2014 Sep 02; Vol. 9 (9), pp. e103015. Date of Electronic Publication: 2014 Sep 02 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target.

  • Authors : Tomecki R; Department of Biophysics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland, Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106 Warsaw, Poland and International Institute of Molecular and Cell Biology, Trojdena 4, 02-109 Warsaw, Poland.; Drazkowska K

Subjects: Mutation*; Exosome Multienzyme Ribonuclease Complex/Exosome Multienzyme Ribonuclease Complex/Exosome Multienzyme Ribonuclease Complex/*genetics ; Multiple Myeloma/Multiple Myeloma/Multiple Myeloma/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2014 Jan; Vol. 42 (2), pp. 1270-90. Date of Electronic Publication: 2013 Oct 22.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The polycomb group protein enhancer of zeste homolog 2 (EZH 2) is an oncogene that influences myeloma cell growth and the mutant ras phenotype.

  • Authors : Croonquist PA; The Graduate Program in Molecular, Cellular, Developmental Biology, and Genetics, University of Minnesota, Minneapolis, MN 55455, USA.; Van Ness B

Subjects: Genes, ras* ; Mutation*; Cell Division/Cell Division/Cell Division/*genetics

  • Source: Oncogene [Oncogene] 2005 Sep 15; Vol. 24 (41), pp. 6269-80.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

An unusual H-Ras mutant isolated from a human multiple myeloma line leads to transformation and factor-independent cell growth.

  • Authors : Crowder C; Laboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Kopantzev E

Subjects: Genes, ras*/Genes, ras*/Genes, ras*/physiology ; Mutation*; Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*genetics

  • Source: Oncogene [Oncogene] 2003 Feb 06; Vol. 22 (5), pp. 649-59.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations.

  • Authors : Ronchetti D; Hematology Service, Department of Medical Sciences, Università degli Studi, Ospedale Maggiore IRCCS, Milan, Italy.; Greco A

Subjects: Chromosomes, Human, Pair 14* ; Chromosomes, Human, Pair 4* ; Mutation*

  • Source: Oncogene [Oncogene] 2001 Jun 14; Vol. 20 (27), pp. 3553-62.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Somatic hypermutation of immunoglobulin variable region genes: focus on follicular lymphoma and multiple myeloma.

  • Authors : Kosmas C; First Department of Medicine, University of Athens School of Medicine, Laikon General Hospital, Greece.; Stamatopoulos K

Subjects: Mutation*; Immunoglobulin Variable Region/Immunoglobulin Variable Region/Immunoglobulin Variable Region/*genetics ; Lymphoma, Follicular/Lymphoma, Follicular/Lymphoma, Follicular/*genetics

  • Source: Immunological reviews [Immunol Rev] 1998 Apr; Vol. 162, pp. 281-92.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print Cited Medium: Print ISSN: 0105-2896 (Print)

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Academic Journal

Identification of conserved skeletal enhancers associated with craniosynostosis risk genes

Subjects: Biological Sciences; Genetics; Human Genome

  • Source: Human Molecular Genetics. 33(10)

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Academic Journal

Low- and High-Grade Glioma-Associated Vascular Cells Differentially Regulate Tumor Growth.

Subjects: Humans; Glioma; Animals

  • Source: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 22(7)

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Academic Journal

Genetic diversity of 1,845 rhesus macaques improves genetic variation interpretation and identifies disease models

Subjects: Biological Sciences; Bioinformatics and Computational Biology; Genetics

  • Source: Nature Communications. 15(1)

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Academic Journal

Clock gene homologs lin-42 and kin-20 regulate circadian rhythms in C. elegans

Subjects: Biochemistry and Cell Biology; Biological Sciences; Neurosciences

  • Source: Scientific Reports. 14(1)

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  • 1-10 of  16,267 نتائج ل ""Animals""