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  • 1-10 ل  417 نتائج ل ""TUMOR suppressor proteins""
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Academic Journal

BIN2 inhibition suppress ovarian cancer progression meanwhile protect ovarian function through downregulating HDAC1 and RPS6 phosphorylation respectively.

  • Authors : Li CR; Department of Gynaecology and Obstetrics, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; State Key Lab of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, Jiangsu, China.

Subjects: Histone Deacetylase 1*/Histone Deacetylase 1*/Histone Deacetylase 1*/metabolism ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/genetics

  • Source: Clinical and translational medicine [Clin Transl Med] 2024 Oct; Vol. 14 (10), pp. e70051.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Editorial & Opinion

Metastasis-enhancing protein KITENIN confers temozolomide resistance on glioblastoma with unmethylated MGMT via upregulation of cancer stem cell makers.

  • Authors : Ahn EJ; Department of Neurosurgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.; Department of Pathology, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism

  • Source: Clinical and translational medicine [Clin Transl Med] 2024 Aug; Vol. 14 (8), pp. e1804.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

Extracellular vesicles miR-31-5p promotes pancreatic cancer chemoresistance via regulating LATS2-Hippo pathway and promoting SPARC secretion from pancreatic stellate cells.

  • Authors : Qin C; Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, P. R. China.; Key Laboratory of Research in Pancreatic Tumor, Chinese Academy of Medical Sciences, Beijing, P.R. China.

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism

  • Source: Journal of extracellular vesicles [J Extracell Vesicles] 2024 Aug; Vol. 13 (8), pp. e12488.Publisher: Wiley Country of Publication: United States NLM ID: 101610479 Publication Model: Print Cited Medium: Internet

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Report

Hepatic loss of CerS2 induces cell division defects via a mad2-mediated pathway.

  • Authors : Cao M; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.

Subjects: Cell Division/Cell Division/Cell Division/*genetics ; Liver/Liver/Liver/*metabolism ; Mad2 Proteins/Mad2 Proteins/Mad2 Proteins/*drug effects

  • Source: Clinical and translational medicine [Clin Transl Med] 2022 Jan; Vol. 12 (1), pp. e712.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway.

  • Authors : Zhang Y; Department of Gastroenterology and Hepatology, the First Affiliated Hospital, Sun Yat-sen University, No.58 Zhongshan 2nd Road, Guangzhou, 510630, China.; Department of Hepatobiliary surgery, the Third Affiliated Hospital, Sun Yat-sen University, No.600 Tian he Road, Guangzhou, 510630, China.

Subjects: Cyclin-Dependent Kinase 4/Cyclin-Dependent Kinase 4/Cyclin-Dependent Kinase 4/*drug effects ; Cyclin-Dependent Kinase 6/Cyclin-Dependent Kinase 6/Cyclin-Dependent Kinase 6/*drug effects ; Hippo Signaling Pathway/Hippo Signaling Pathway/Hippo Signaling Pathway/*drug effects

  • Source: Clinical and translational medicine [Clin Transl Med] 2021 Aug; Vol. 11 (8), pp. e503.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Report

Deleted in malignant brain tumor 1 genetic variation confers urinary tract infection risk in children and mice.

  • Authors : Hains DS; Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.; Polley S

Subjects: Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics ; Tumor Suppressor Proteins/Tumor Suppressor Proteins/Tumor Suppressor Proteins/*genetics

  • Source: Clinical and translational medicine [Clin Transl Med] 2021 Jul; Vol. 11 (7), pp. e477.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

Aberrant expression of LncRNA CASC2 mediated the cell viability, apoptosis and autophagy of colon cancer cells by sponging miR-19a via NF-κB signaling pathway.

  • Authors : Zhang P; Affiliated Hospital of Shaanxi University of Chinese Medicine, Xi'an City, China.; Pan Y

Subjects: Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*pathology ; Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/*physiology ; MicroRNAs/MicroRNAs/MicroRNAs/*metabolism

  • Source: International journal of experimental pathology [Int J Exp Pathol] 2021 Jun; Vol. 102 (3), pp. 163-171. Date of Electronic Publication: 2021 May 13.Publisher: Wiley Country of Publication: England NLM ID: 9014042 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The morphologic spectrum of germline-mutated BAP1-inactivated melanocytic tumors includes lesions with conventional nevic melanocytes: A case report and review of literature.

  • Authors : Wysozan TR; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana.; Khelifa S

Subjects: Germ-Line Mutation* ; Melanocytes*/Melanocytes*/Melanocytes*/metabolism ; Melanocytes*/Melanocytes*/Melanocytes*/pathology

  • Source: Journal of cutaneous pathology [J Cutan Pathol] 2019 Nov; Vol. 46 (11), pp. 852-857. Date of Electronic Publication: 2019 Jul 04.Publisher: Wiley Country of Publication: United States NLM ID: 0425124 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

JCAD deficiency delayed liver regenerative repair through the Hippo-YAP signalling pathway.

  • Authors : Zhang L; Department of Medical Microbiology & Parasitology, MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Fudan University Shanghai Medical College, Shanghai, China.; Yang YY

Subjects: Liver Regeneration*/Liver Regeneration*/Liver Regeneration*/genetics ; Liver Transplantation* ; Cell Adhesion Molecules*/Cell Adhesion Molecules*/Cell Adhesion Molecules*/metabolism

  • Source: Clinical and translational medicine [Clin Transl Med] 2024 Mar; Vol. 14 (3), pp. e1630.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Report

BCL11B promotes T-cell acute lymphoblastic leukaemia cell survival via the XRCC5/C11ORF21 axis.

  • Authors : Yu X; The First Affiliated Hospital and Institute of Hematology, School of Medicine, Jinan University, Guangzhou, Guangdong, China.; Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, Guangdong, China.

Subjects: Transcription Factors* ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/genetics; Humans

  • Source: Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1580.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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  • 1-10 ل  417 نتائج ل ""TUMOR suppressor proteins""