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Combination Antimalarials in Uncomplicated Malaria

• Authors : World Health Organization; Medical Research Council, South Africa; Global Fund ...

• Source: Open Label Study to Evaluate Combination Anti-malarial Therapy,in Terms of Efficacy, Prevalence of Gametocyte Carriage and Molecular Markers Associated With Sulfadoxine Pyrimethamine Resistance in

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A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria

• Authors : World Health Organization; Medical Research Council, South Africa; Global Fund

• Source: Open Label Drug Study (With Single and Parallel Group Components) to Evaluate Combination Antimalarial Therapy for Efficacy, Gametocyte Carriage and Molecular Markers Associated With SP Resistance in

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The crystal structure of halofantrine–ferriprotoporphyrin IX and the mechanism of action of arylmethanol antimalarials.

• Authors : de Villiers, Katherine A; Marques, Helder; Egan, Timothy J

Subjects: Malaria; Antimalarials; Halofantrine

• Source: Journal of Inorganic Biochemistry ; http://www.journals.elsevier.com/journal-of-inorganic-biochemistry/

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Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials

• Authors : Nsumiwa, Samkele; Egan, Timothy J; Chibale, Kelly

Subjects: Chemistry; UCTD; Doctoral

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Quantum dot labelled antimalarials and investigation of their interaction with synthetic haemozoin

• Authors : Ganazzoli, Giacomo;

Subjects: Chemistry

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The role of haem in the mechanism of action of antimalarials in Plasmodium falciparum

• Authors : Combrinck, Jill Michelle;

Subjects: Pharmacology; digestive, oral, and skin physiology; parasitic diseases

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Insights into the mechanism of action of quinoline antimalarials against Plasmodium falciparum revealed by novel fluorescent analogues and chemical proteomics

• Authors : Woodland, John Geoffrey;

Subjects: Chemistry

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Quinoline antimalarials decrease the rate of beta-hematin formation

• Authors : Egan, Timothy J; Ncokazi, Kanyile K

Subjects: b-Hematin; Hemozoin; Chloroquine

• Source: Journal of Inorganic Biochemistry ; http://www.sciencedirect.com/science/journal/01620134

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Single and hybrid antimalarials based on artemisinin, chloroquine and ß-lactams : synthesis, antiplasmodial activity, cytotoxicity and effect of selected artemisinin-chloroquine hybrids on the parasitic endocytosis pathway

• Authors : Feng, Tzu-Shean;

Subjects: Chemistry

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Towards a fragment approach to haemozoin inhibiting antimalarials : exploration of coordination and π-stacking interactions with Fe(III)PPIX by spectroscopy and synthesis

• Authors : Kuter, David;

Subjects: Chemistry

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