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Publisher : springer nature

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Academic Journal

MicroPET imaging of bacterial infection with nitroreductase-specific responsive 18F-labelled nitrogen mustard analogues.

Authors : Huang, Lumei^1,2; Fang, Jianyang^1,2; Hong, Shouqiang¹

Source: European Journal of Nuclear Medicine & Molecular Imaging. Jul2022, Vol. 49 Issue 8, p2645-2654. 10p. 1 Diagram, 6 Graphs.

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Academic Journal

Dual-therapeutic reporter genes fusion for enhanced cancer gene therapy and imaging.

Authors : Sekar, T V¹; Foygel, K¹; Willmann, J K¹

Source: Gene Therapy. May2013, Vol. 20 Issue 5, p529-537. 9p. 1 Color Photograph, 1 Chart, 4 Graphs.

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Academic Journal

Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals.

Authors : Bhaumik, S¹; Sekar, T V²; Depuy, J¹

Source: Gene Therapy. Mar2012, Vol. 19 Issue 3, p295-302. 8p. 2 Color Photographs, 1 Diagram, 3 Graphs.

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Academic Journal

Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo.

Authors : Harvey, T J¹; Hennig, I M¹; Shnyder, S D²

Source: Cancer Gene Therapy. Nov2011, Vol. 18 Issue 11, p773-784. 12p. 1 Black and White Photograph, 1 Diagram, 2 Charts, 4 Graphs.

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Academic Journal

E. coli nitroreductase/CB1954 gene-directed enzyme prodrug therapy: role of arylamine N-acetlytransferase 2.

Authors : Mitchell, D. J.¹; Minchin, R. F.¹

Source: Cancer Gene Therapy. Nov2008, Vol. 15 Issue 11, p758-764. 7p. 1 Diagram, 2 Graphs.

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Academic Journal

Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo.

Authors : White, C. L.¹; Menghistu, T.¹; Twigger, K. R.¹

Source: Gene Therapy. Mar2008, Vol. 15 Issue 6, p424-433. 10p. 1 Chart, 7 Graphs.

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Academic Journal

The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411NTR.

Authors : Singleton, D. C.¹; Li, D.¹; Bai, S. Y.¹

Source: Cancer Gene Therapy. Dec2007, Vol. 14 Issue 12, p953-967. 15p. 1 Color Photograph, 1 Black and White Photograph, 2 Charts, 6 Graphs.

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Academic Journal

Direct positive selection for improved nitroreductase variants using SOS triggering of bacteriophage lambda lytic cycle.

Authors : Guise, C. P.¹; Grove, J. I.^1,2; Hyde, E. I.³

Source: Gene Therapy. Apr2007, Vol. 14 Issue 8, p690-698. 9p. 1 Diagram, 2 Charts, 5 Graphs.

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Academic Journal

Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo.

Authors : Theys, J.¹; Pennington, O.²; Dubois, L.¹

Source: British Journal of Cancer. 11/6/2006, Vol. 95 Issue 9, p1212-1219. 8p. 2 Charts, 2 Graphs.

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Academic Journal

Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70.

Authors : Djeha, Hakim A¹; Todryk, Stephen M²; Pelech, Steven³

Source: Cancer Gene Therapy. Jun2005, Vol. 12 Issue 6, p560-571. 12p.

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نتائج البحث

فلترة النتائج

MicroPET imaging of bacterial infection with nitroreductase-specific responsive 18F-labelled nitrogen mustard analogues.

Dual-therapeutic reporter genes fusion for enhanced cancer gene therapy and imaging.

Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals.

Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo.

E. coli nitroreductase/CB1954 gene-directed enzyme prodrug therapy: role of arylamine N-acetlytransferase 2.

Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo.

The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411NTR.

Direct positive selection for improved nitroreductase variants using SOS triggering of bacteriophage lambda lytic cycle.

Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo.

Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70.

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