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Discovery of small molecules binding to the normal conformation of prion by combining virtual screening and multiple biological activity evaluation methods.

• Authors : Li L; State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou, 730000, People's Republic of China.; Wei W

Subjects: Prions*/Prions*/Prions*/antagonists & inhibitors ; Prions*/Prions*/Prions*/metabolism; Drug Evaluation, Preclinical

• Source: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2017 Dec; Vol. 31 (12), pp. 1053-1062. Date of Electronic Publication: 2017 Nov 20.Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Print-Electronic Cited Medium:

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