Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Pathogenic postzygotic mosaicism in the tyrosine receptor kinase pathway: potential unidentified human disease hidden away in a few cells.

Subjects: Germ-Line Mutation* ; Mosaicism*; Fibrous Dysplasia, Polyostotic/Fibrous Dysplasia, Polyostotic/Fibrous Dysplasia, Polyostotic/*genetics

  • Source: The FEBS journal [FEBS J] 2021 May; Vol. 288 (10), pp. 3108-3119. Date of Electronic Publication: 2020 Sep 05.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM

تفاصيل العنوان

×
Academic Journal

Qualitative Ras pathway signature for cetuximab therapy reveals resistant mechanism in colorectal cancer.

  • Authors : Song K; Department of Systems Biology, College of Bioinformatics Science and Technology, Harbin Medical University, China.; Lu H

Subjects: Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism ; Cetuximab/Cetuximab/Cetuximab/*pharmacology ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*drug therapy

  • Source: The FEBS journal [FEBS J] 2020 Dec; Vol. 287 (23), pp. 5236-5248. Date of Electronic Publication: 2020 Apr 20.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM

تفاصيل العنوان

×
Academic Journal

Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α.

  • Authors : Echeverria I; Department of Bioengineering and Therapeutic Sciences, School of Pharmacy, University of California at San Francisco, CA, USA.; Department of Pharmaceutical Chemistry, School of Pharmacy, University of California at San Francisco, CA, USA.

Subjects: Mutation* ; Oncogenes*; Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/*chemistry

  • Source: The FEBS journal [FEBS J] 2015 Sep; Vol. 282 (18), pp. 3528-42. Date of Electronic Publication: 2015 Jul 24.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM

تفاصيل العنوان

×
Academic Journal

Specific inhibition of PI3K p110δ inhibits CSF-1-induced macrophage spreading and invasive capacity.

  • Authors : Mouchemore KA; School of Medicine and Pharmacology, The University of Western Australia, Crawley, Western Australia, Australia.; Sampaio NG

Subjects: Cell Movement* ; Phosphoinositide-3 Kinase Inhibitors*; Macrophage Colony-Stimulating Factor/Macrophage Colony-Stimulating Factor/Macrophage Colony-Stimulating Factor/*metabolism

  • Source: The FEBS journal [FEBS J] 2013 Nov; Vol. 280 (21), pp. 5228-36. Date of Electronic Publication: 2013 Jun 05.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM

تفاصيل العنوان

×
Academic Journal

Mouse models of PIK3CA mutations: one mutation initiates heterogeneous mammary tumors.

  • Authors : Koren S; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.; Bentires-Alj M

Subjects: Mutation, Missense*; Mammary Neoplasms, Experimental/Mammary Neoplasms, Experimental/Mammary Neoplasms, Experimental/*genetics ; Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/*genetics

  • Source: The FEBS journal [FEBS J] 2013 Jun; Vol. 280 (12), pp. 2758-65. Date of Electronic Publication: 2013 Mar 01.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM

تفاصيل العنوان

×
Academic Journal

Extended treatment with selective phosphatidylinositol 3-kinase and mTOR inhibitors has effects on metabolism, growth, behaviour and bone strength.

  • Authors : Smith GC; Department of Molecular Medicine and Pathology, University of Auckland, New Zealand.; Ong WK

Subjects: Phosphoinositide-3 Kinase Inhibitors*; Behavior, Animal/Behavior, Animal/Behavior, Animal/*drug effects ; Body Composition/Body Composition/Body Composition/*drug effects

  • Source: The FEBS journal [FEBS J] 2013 Nov; Vol. 280 (21), pp. 5337-49. Date of Electronic Publication: 2013 Aug 12.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM

تفاصيل العنوان

×
  • 1-6 ل  6 نتائج ل ""Class I Phosphatidylinositol 3-Kinases""